• Worked as Scientist (S-IV),} under DGHS, The Dte General of Health Services, Ministry Of Health and F.W, Nirman Bhawan New Delhi. • Involved in the development/establishments of Metro Blood Banks andNational Plasma Fractionation Centre (NPFC) and submitted DPR Detailed Project Report for NPFC duly Approved by CCEA Cabinet Committee Of Economic Affairs Govt Of India. This is under active consideration in National AIDS Control Organization (NACO) in Phase III programme for its implementation. • Imparted practical training/technical support for Immunochemical and Biochemical Quality Control of Human Blood products as per the pharmacopeia standards at National Institute of Biologicals, Noida under Ministry Of Health and F.W, Nirman Bhawan New Delhi. Looked after the following items of work under DGHS at Nirman Bhawan; • Blood Transfusion Authority, • Development of Metro Blood Banks, • Blood Transfusion Medicine, • Plasma Fractionation Centre.

Joint Director• Headed the biochemistry divisions of Central Drugs Laboratory (CDL) and Quality control division (QCD) at Central Research Institute, Kasauli, H.P, INDIA. • Performed regularly biochemica/ immunochemcal quality control tests on different imported and indigenously manufactured immunobiologicals (vaccines, sera and blood products) by using standard procedures to meet the EPI and commercial demand of the country. • Prepared and undertook measures for quality control of human diagnostic reagents. • Implemented and regulated quality control of different raw materials and animal feeds used in the production and testing of Immunobiologicals. Assistant Director GeneralWorked as ADG (PFA) in the field related to implementation and administration of Prevention of Food adulteration act and rules 1954 under DGHS, Ministry Of Health and F.W, Nirman Bhawan New Delhi.

• Nominated by the Ministry of Health and Family Welfare, Govt. of India to undergo an extensive training for one year (25-3-91 to 8-3-1992) in three different Premier Institutes in United Kingdom in “Fractionation of Human Plasma for the Manufacturing and Quality control of Human Blood Products, Preparation of Blood Components and Blood Grouping Reagents to be used both for therapeutic and diagnostic purposes.” a) Bio Products Laboratory (B.P.L) Elstree, U.K. b) Blood Transfusion Services, Brentwood U.K, c) National Institute of Biological Standards and Control, Potters Bar, U.K • Prepared & standardized immunochemically pure IgG fractions and raised their corresponding Anti IgG species specific antisera (against different animal species). • Prepared and undertook measures for quality control of human diagnostic reagents (Anti IgG, IgA and IgM heavy chain specific antisera). • Conducted studies with these reagents: to understand various immunological disorders, to identify heavy chain diseases in cancer patients sera and did experiments for conjugated antibodies.

• For the first time in India fractionated, isolated, characterized and standardized different classes of Immunochemically pure human serum Immunoglobulins viz IgG, IgA and IgM and raised their Heavy-Chain Specific Anti-Human Sera IgG ( ), IgA ( ), and IgM ( ) diagnostic reagents. • The World Health Organization (W.H.O) Reference laboratory at Birmingham U.K has approved and certified the quality of these reagents as being at par with W.H.O Ref.standards and other commercially available imported reagents. • Prepared globulin reagent and raised antisera against different animal species to regularly supply the polyvalent whole anti-globulin sera to meet the entire demand of the country for medico – legal and food adulteration cases. • Strengthened and implemented procedures for the up-gradation of the Animal house.

• Imparted regularly theoretical and practical teaching to the STD trainees in the field of Electrophoresis/Gel Diffusion techniques. • Taught in the field of Biochemistry to B.Sc (Microbiology) students.• Trained Drug Control Inspectors in the field of testing human blood products.

• Therapeutic production: - Large scale fractionation of human plasma and the production of The following for clinical use. Factor VIII, Factor IX, Albumin 4.5% and 20% Normal Immunoglobulins, intramuscular, Specific Immunoglobulin. • Diagnostic Production: - Formulation and production of a range of human blood-grouping Reagent their quality control and performed a range of serological tests. • Quality Control: - Testing of in- process and finished product of therapeutic blood products in Analytical chemistry Coagulation assay, Virology and Bacteriology.• Had an access to all standard operating procedures

• Closely involved in the collection, testing, processing and distribution of a blood donation. • Plasmapheresis and plateletpheresis techniques. • Screening of HIV 1 and 2, Hepatitis B and C. • Gained experience in production and quality monitoring of various blood components, such as Platelet Concentrate, Cryoprecipitate, RBC concentrate, Fresh Frozen Plasma etc . • Anti D Quantification of both raw material and the anti D immunoglobulin • Learnt techniques for preservation and freezing of red cells, and its recovery • Preparation of red cell panels and antibody identification by different methods. • Production and quality control of blood grouping reagents.

• Carried out a programme of work on the quality control of coagulation factors concentrate (factors, VIII, IX and Antithrombin) albumins, thrombolytic drugs and immunoglobulins. . • Detection and testing of blood- borne viruses, HIV and Hepatitis B and C.

• Certified and Approved as Manufacturing Chemist for Human Blood Products (Biological Products by Directorate of Health Services of Haryana, India. • Trained under Bulgarian Technologists in a foreign collaborated pharmaceutical ltd .Co for the manufacturing and quality control of Human Blood Products on industrial scale derived from; Human Placentea, Retroplacental Serum. • Independently discharged the Technical Functions to meet the international/internal demand and standards of Human Blood Products including the testing for the blood- borne viruses. • Performed and standardized various latest immunological / chemical/ biochemical/ serological/ coagulation assays/ ultrafiltration/ gel-filtration / ion exchange chromatographic techniques and handled sophisticated laboratory equipments, plant and machinery used both for manufacturing and Quality control of Human Blood Products. • Engaged in research and development activities to develop new technologies to economise the process for increasing and maintaining the quality of Human Blood Products. • Imparted training to the technical staff and sales representative in the field of manufacturing and quality control of human blood products.