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I’m a creative scientific bio-entrepreneur appreciated for my pioneering vision. Laureate of the 2022 Breakthrough Prize.[Today]: One Health actor through the AI based discovery of innovative and patentable mixes of edibles with optimal biological activities to preserve people and their animals from devastating diseases. [2001]: predictive medicine pioneer, championing a tractable “personal genome card” concept[1996]: inventing and championing a new massively parallel DNA sequencing technology, now sold by Illumina and capturing > 75% of the sequencing market.My background encompasses several research, management, founder and executive positions in academia, multinational pharmaceutical companies and start-ups. I co-authored 17 peer-reviewed publications and 12 patent applications, comprising princeps patents protecting Illumina's massively parallel sequencing technology. I earned my Ph.D in macromolecular biophysics from the Louis Pasteur University (now Université de Strasbourg), in Strasbourg (France).Skills : - Company founding and management, team building- Business opportunity identification, evaluation and development- Bacterial Biofilm science- Drug & biomarker discovery- Technology invention and development: DNA sequencing and genotyping, immuno-hematology assays, DNA amplification methods and DNA based computing- Data-crunshing: images and data analysis (algorithms and software), bio-physical modeling
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CeoAlphanososRiom, Fr
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CeoAlphanosos May 2015 - PresentRiom, Auvergne, Fr -
Co-FounderAlphanosos May 2014 - PresentRiom, Auvergne, Fr- Scientific and business strategy definition- Business plan and operational planning- Fund raising activities- Company creation- Business and partnership development
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Associated ProfessorUniversité De Strasbourg Oct 2024 - PresentStrasbourg, Grand Est, FrAffiliated to ISIS, Institut de Science et d’Ingénierie Supramoléculaires. https://isis.unistra.fr/about-isis-2/ -
Honorary ChairInstitute For Advanced Study Of The University Of Strasbourg (Usias). May 2023 - Presenthttps://www.usias.fr/en/
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OwnerPascal Mayer Consulting May 2014 - PresentScientific, technological, strategic and managerial consultancy services
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Vp Science & Business DevelopmentBiofilm Control Jul 2009 - Apr 2014- General and strategic management as #2 of the company. Co-authored the business plan that enabled successful fund raising of 3M€ from French private and corporate investors in 2012. In charge of international business development. - Championed the reorientation of the business model from microbiology R&D tool provider to high value diagnostic and treatment orientation test developer in the fields of immuno-hematology, cancer and infections. Driving the licensing discussions. - Previously in charge of company technical and scientific direction, communication and operational issues, pharmaceutical discovery, management of the scientific team, experimental design and statistical data analysis for clinical and industrial biomarker discovery in the field of bacterial biofilms,- Co-inventor of two patent applications in the field of biofilms and affinity/imunodetection technologies.
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Cso & PresidentHaploys Jan 2004 - Jun 2009- In charge of company creation and shut-down, fund raising with governmental authorities, general and technological management, market definition, scientific strategy and key technological innovations. - Management of the scientific team (1 scientist, 1engineer, and 1 technician). - Successfully lead commercial activities- Developed neuro-genetic algorithms and software for extrapolation of time-series and finding the genetic roots of quantitative traits (C++).- Developed fast algorithms and software for massively parallel sequencing data assembly (C++).- Developed new genotyping methods and a new isothermal DNA amplification method.- Designed and realized an improved chemiluminescence’s imaging instrument and associated image acquisition and visualization software (C++/MFC, Windows).- inventor of 1 patent.
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CsoManteia Predictive Medecine Jan 2001 - Dec 2003• In charge of the scientific strategy, advanced scientific and technological input and innovations, and scientific issues with investors and external collaborators, in particular in the field of medical genetics.• Participated (transiently hands-on) in the development of the technological concepts to enable, among others, 100 million bases per second sequencing instruments, fast “single test-tube” genome wide genotyping methods addressing up to 1 million SNPs per individual and “single test-tube” genome sequencing methods, now the core of Illumina’s genome sequencing technology. • Defined the R&D strategy and the initial technology development project; designed the laboratories.• Hired and build up the scientific team (~36 people). Managed 5 direct reports (lab-manager and department heads: chemistry, molecular biology, bio-informatics, instrumentation and micro-fluidics) and transiently up to 10 scientists (computer science, statistics, molecular biology).• Initiated and followed a collaboration with University of Ottawa (physics of DNA colony growth) and Imperial College London (one PhD student direct co-supervision, statistical genetic data analysis)• co-inventor of 2 patents, co-authored 1 peer-reviewed publication
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ScientistSerono Pharmaceutical Research Institute Jan 1998 - Dec 2000• Championned the development of a new massively parrallel DNA sequencing method and animated the team of 10 scientists and technicians working on the invention and supervised directly 2 research technicians. • Initiated external collaborations on microfluidics with IMT, Neuchatel, Switzerland, and on polymer dynamics with the department of physics, University of Ottawa, Canada.• Developed biochemical assays, fluorescent detection methods, automated setup and software (real-time image analysis and multi threaded automation, C++ under Windows NT4 ).• co-inventor of 2 patents, co-authored of 1 peer-reviewed publication.
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ScientistGlaxowellcome Oct 1996 - Dec 1997Brentford, Middlesex, Gb• In charge of providing the company with new proprietary genomics methods.• Initiated and planned the development of a new massively parrallel DNA sequencing method.• co-inventor of 2 patents. -
Post-Doctoral FellowCentre De Recherche Paul Pascal, Cnrs Oct 1994 - May 1996• In charge of the video-microscopy developments in the framework of an European project aiming to develop new DNA separation methods.• Pioneered a new method for electrophoretic separation of chromosomal DNA and various colloidal particles based on magnetically structured ferrofluid arrays in a micro-capillary electrophoresis setup.• Wrote real-time video-images acquisition software for scientific use (C++ code under X/UNIX). • Invented a method and wrote software to analyze video-microscopy images of moving fuzzy objects (DNA molecules) using spatio-temporal correlation maps. • Co-inventor of 1 patent, co-authored 1 peer-reviewed publication
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Post-Doctoral FellowUniversity Of Ottawa Nov 1991 - Aug 1994Ottawa, On, Ca• In charge of the characterization of gel electrophoresis of single stranded DNA. in order to optimize DNA sequencing methods.• Wrote software (8,000 lines of C++ code under MS-Windows) to measure the migrated distance of DNA fragments on scanned autoradiogram. • Demonstrated an artifact in velocity measurements performed in denaturing polyacrylamide gels and invented a method to properly measure the velocities.• Showed that and how a new free solution DNA separation method could dramatically enhance DNA sequencing methods.• Wrote a macromolecular dynamics simulation program with an assembler code core.• Supervised undergraduate students.• co-inventor of 1 patent, co-authored 7 peer-reviewed publications
Pascal Mayer Skills
Pascal Mayer Education Details
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Université Louis Pasteur (Strasbourg I)Biophysique Macromoléculaire -
IpmeGeneral Management And Business Administration
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Université Louis Pasteur (Strasbourg I)Molecular Biology
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Lycée Jean Moulin
Frequently Asked Questions about Pascal Mayer
What company does Pascal Mayer work for?
Pascal Mayer works for Alphanosos
What is Pascal Mayer's role at the current company?
Pascal Mayer's current role is CEO.
What is Pascal Mayer's email address?
Pascal Mayer's email address is pa****@****neuf.fr
What schools did Pascal Mayer attend?
Pascal Mayer attended Université Louis Pasteur (Strasbourg I), Ipme, Université Louis Pasteur (Strasbourg I), Lycée Jean Moulin.
What skills is Pascal Mayer known for?
Pascal Mayer has skills like Molecular Biology, Dna, Sequencing, Genetics, Biofilms, Molecular Diagnostics, Life Sciences, R&d, Biomarker Discovery, Business Strategy, Biotechnology, Microbiology.
Who are Pascal Mayer's colleagues?
Pascal Mayer's colleagues are Daniel Valtueña Maestre, Fatima Ezzaouia, Manuel Fourneyron.
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