Springworks Therapeutics is a clinical-stage biopharmaceutical company that identifies and advances promising science and pioneers efficient pathways for drug development for patients with rare diseases and cancer.

• Developed immediate release and modified release oral formulations using wet granulation and dry granulation techniques• Responsibilities include managing tight deadlines for multiple projects involving formulation development and manufacturing of solid dosage form ranging from pre-clinical phase up to commercial stage• Scale up and tech transfer• CMC project management

• Developed curcumin based hydrolytically degradable crosslinked polymer hydrogel films for controlled drug delivery; achieving a degradation time from 3 hours to 7 days• Worked on microparticles synthesis of poly(curcumin β-amino esters) to be used in oral, topical and parenteral formulations• Synthesized pro-drug tablet formulations for a hydrophobic drug and studied the stability according to USP specifications• Determined the accurate composition of acrylated curcumin (drug) monomer mixture through preformulation characterizations techniques viz., LCMS and NMR; improved the purity of monomer by 2.5 times • Experience with functionalizing up to 30 – 40 grams of API • Optimized synthesis protocol and solvent selection for synthesis of polymer films of uniform thickness• Effect of composition and amine on molecular relaxation properties of crosslinked polymer networks was studied using dielectric spectroscopy (DEA) and dynamic mechanical analysis (DMA)