Patrick Horn Email & Phone Number

C-Suite experienced physician scientist with 20+ years of strategic and operational experience in large pharmaceutical and smaller biopharmaceutical companies including publicly traded and privately held companies. Proven track record in designing, initiating, and managing Phase 1 through 4 clinical trials, including complex global trials. Phase 1 program experience includes many therapeutics areas (neurology, pain management, antiviral, antibiotic, gastroenterology, renal disease) other than oncology. Pivotal Phase 3 program experience include rare diseases, liver diseases and bacterial infections; all of which include successful regulatory approvals. Therapeutic modalities include small molecules, protein therapeutics, enzyme replacement therapy and oligonucleotides.Other areas of expertise/experience include:• Executive Leadership including corporate strategy development• Regulatory strategy development, authoring regulatory documents, and extensive regulatory interactions with the FDA (INDs, NDAs, and Advisory Committee Meeting presentation) and the EMA (scientific advice, MAAs)• Interface with Board of Directors and the Investor Community including participation in private funding rounds, an IPO and multiple public follow-on rounds• Building and leading high performing teams to support clinical development (medical groups, clinical operations, biometrics) and to support product launch and commercialization (medical affairs and pharmacovigilance) • Public speaking/presentation of clinical trial results (scientific meetings, investor conferences, patient organizations) and publication of clinical trial results (NEJM, JAMA, Lancet)

Listed skills include Clinical Pharmacology.