Patrick J. Mulcahey Email and Phone Number

Lab of Dr. Z. Josh Huang

Lab of Dr. Noreen Bukhari-Parlakturk

I work in multiple projects in the lab:1. Mechanisms of Ictal High Frequency Oscillations Responsibilities:-to lead a collaboration between the Epilepsy Lab and a University of Pennsylvania bioengineering lab-to develop novel methods based on in vivo electrophysiology and two photon multicellular calcium imaging to study the mechanisms of HFOs, a biomarker of epilepsy-to develop novel MATLAB-based analyses and theoretical simulations to generate hypotheses with potential… Show more I work in multiple projects in the lab:1. Mechanisms of Ictal High Frequency Oscillations Responsibilities:-to lead a collaboration between the Epilepsy Lab and a University of Pennsylvania bioengineering lab-to develop novel methods based on in vivo electrophysiology and two photon multicellular calcium imaging to study the mechanisms of HFOs, a biomarker of epilepsy-to develop novel MATLAB-based analyses and theoretical simulations to generate hypotheses with potential translational relevance2. Epileptic Seizures in Mouse Models of CDKL5 Deficiency DisorderResponsibilities:-to serve as point of contact in a collaboration between the Epilepsy Lab and a University of Pennsylvania genetics lab-to read, interpret, and perform computational analysis on iEEG data from chronically epileptic mice-to interface with a physician scientist and frame our findings in from a perspective of clinical translation3. Closed Loop Neuromodulation in a Mouse Model of Intractable EpilepsyResponsibilities:-to obtain independent funding for my work through Sigma Xi Grants in Aid of Research-to implement a deep learning paradigm for seizure detection in chronically epileptic mice-to build and test a closed loop optogenetic neuromodulation system based on a Raspberry Pi computer Show less

Various ProjectsResponsibilities:-to write IRBs, recruit subjects for our ongoing studies, and maintain subject privacy standards in accordance with HIPAA-to supervise a team of students as they pursue their own independent projects in the clinic-to interface with consultants and orthopedic engineering firms to develop technologies for improved scoliosis assessment and correction

Lab of Dr. Jong-in HahmI worked on two major projects in the lab:1. Plasmonic Nanoparticle Coupled Zinc Oxide Nanorod Arrays as Enhanced Light Detection Platforms (September 2016 - May 2019) Responsibilities: -to carry out all relevant photovoltage and photocurrent experiments for the project -to analyze and present the data to Dr. Hahm and other group members to closely monitor the progress of the work -to be… Show more Lab of Dr. Jong-in HahmI worked on two major projects in the lab:1. Plasmonic Nanoparticle Coupled Zinc Oxide Nanorod Arrays as Enhanced Light Detection Platforms (September 2016 - May 2019) Responsibilities: -to carry out all relevant photovoltage and photocurrent experiments for the project -to analyze and present the data to Dr. Hahm and other group members to closely monitor the progress of the work -to be familiar with the literature on photodetection and nanoplasmonics2. Characterization and Manipulation of Protein Adsorption and Self Assembly Behavior onto Diblock Copolymer Surfaces (October 2015 - May 2019) Responsibilities: -to work closely with a graduate student to develop analytical methods and to perform analysis on the results of atomic force microscopy experiments -to be familiar with the literature on protein adsorption behavior Show less

I worked with Dr. Flavia Vitale in the Neurotech subgroup, which aims to use novel nanomaterials in bioelectronics and biosensing applications.Ti3C2 MXene Electrodes for Surface ElectromyographyResponsibilities:-to fabricate microelectrode arrays using conventional nanofabrication techniques, such as photolithography, electron beam deposition, and oxygen plasma etching-to characterize the electrical behavior of these microelectrode arrays via electrical impedance… Show more I worked with Dr. Flavia Vitale in the Neurotech subgroup, which aims to use novel nanomaterials in bioelectronics and biosensing applications.Ti3C2 MXene Electrodes for Surface ElectromyographyResponsibilities:-to fabricate microelectrode arrays using conventional nanofabrication techniques, such as photolithography, electron beam deposition, and oxygen plasma etching-to characterize the electrical behavior of these microelectrode arrays via electrical impedance spectroscopy-to apply my electrodes in human subjects to monitor neuromuscular dynamics and to perform muscle cartography Show less

Responsibilities:-to research and write accessible, comprehensive outlines of medical science and wellness topics to create health awareness infographics-to create and manage the startup’s Facebook and Twitter pages to engage the public with our content

Lab of Michael Selzer MD PhD. Local Cytoskeletal Protein Synthesis in Spinal Cord Axon Regeneration in Sea Lamprey Responsibilities: -to work closely with a research scientist to design experiments to detect actin synthesis in regenerating spinal cord neurons following treatment of the axon tips with relevant mRNA-to perform these experiments including molecular syntheses, animal surgery, and immunohistochemistry-to analyze the experimental results and present them to my… Show more Lab of Michael Selzer MD PhD. Local Cytoskeletal Protein Synthesis in Spinal Cord Axon Regeneration in Sea Lamprey Responsibilities: -to work closely with a research scientist to design experiments to detect actin synthesis in regenerating spinal cord neurons following treatment of the axon tips with relevant mRNA-to perform these experiments including molecular syntheses, animal surgery, and immunohistochemistry-to analyze the experimental results and present them to my supervisors Show less