I direct laboratory & clinical research programs focused on brain development, plasticity and recovery following acquired brain injury in newborns. Laboratory research utilizes small animal models of neonatal hypoxic ischemic brain injury that are studied for functional outcome using early EEG and subsequent visual cortical function & plasticity measured with intrinsic signal optical imaging. Clinical research employs advanced magnetic resonance imaging techniques including diffusion tensor imaging, spectroscopy and morphometry in newborns with congenital heart disease, birth asphyxia and following premature birth. I am the UCSF site-PI for the multicenter cooling trial for pediatric cardiac arrest (THAPCA). I serve as attending physician in the Pediatric ICU and Cardiac ICU.-Faculty, Graduate Program in Biomedical Sciences-Faculty, Pathway to Discovery in Molecular Medicine-Faculty, Graduate Education in Medical Sciences-Co-Director Pediatric Neurointensive Care Unit