Patrick Poulin Email & Phone Number

Quebec, Canada

Patrick has developed two Excel templates to facilitate the predictions in the patients of the volume of distribution and clearance as well as the plasma concentration-time profiles of drugs and chemicals. Several recognized methods used to predict the volume of distribution and clearance were compiled. The Wajima allometric method was also compiled to facilitate any animal-to-animal and animal-to-human extrapolation of PK. These two products can be available on request.

Québec City

Consultant for the pharmaceutical industries as well as the regulatory authorities.Act as an independant consultant to support the research and development in preclinical and clinical studies to identify the most promising new drug candidates for the patients. Expert in first-in-human (FIH) dose predictions. Perform expert reviews for the regulatory authorities such as Health Canada. Estimate the heath-based exposure limits in industrial medicine. Conduct toxicological risk assessement.

Montreal, Canada Area

Conduct researches to improve the First-in-Human (FIH) dose projections of new drug candidates with a focus on the drug clearance and volume of tissue distribution. Give lessons in pharmacology and toxicology covering diverse topics. Supervizing MSc and PhD students. Publish manuscripts in peer reviewed journals.

Québec, Quebec, Canada

Give lessons in toxicology in the context of preventive and industrial medicine

Ottawa, Canada Area

Ac as a reviewer for validating the new drug submissions made by the pharmaceutical companies.

Québec City Canada / Washington Dc Usa

Acting as a consultant for PhRMA (Pharmaceutical research and manufacturers of America).Act as the leader consultant for the PhRMA/PISC initiative on predictive models of compound properties, safety and efficacy. Evaluating the prediction performance of diverse methods used to predict the first-in-human pharmacokinetics. Comparing the approaches of PBPK with allometry (Wajima, Dedrick, etc.). Publication of 5 research papers in the Journal of Pharmaceutical Sciences.

Basel Area, Switzerland

Make first-in-human dose projections for each new drug candicate

Basel Area, Switzerland

Development of a new in vitro model of drug tissue distribution to facilitate the development of PBPK model in the pharmaceurtical industry

Doctor In Public Health, Specialized In Toxicology And Pharmacology

Post-Doctorat, Specialized In Pharmaceutical Sciences And New Medicines, Post-Doc

Activities and Societies: Made in collaboration with the Roche Pharma company in Switzerland

Education record