Served as technical primary for all products • Global lithium-ion account management • Technology interface for Investment/Acquisition Team • Ensured internal research met external needs • Curated intellectual property portfolio to maintain competitive edge • Created relationships with key materials providers and partners • Maintained regulatory approval through Horizon 2020 update • Raised >$250k in contracted research projects • VP roles continued (below)

Led energy storage (Lithium Ion, Lead Acid) research through product development lifecycle to global commercialization • Orchestrated fundamental research to provide sustainable competitive advantage for our products • Distilled information and trends into actionable conclusions supporting our global sales team and C-suite • Curated intellectual property portfolio to maintain competitive edge • Restructured R+D team for higher throughput with less people • Coordinated toll manufacturer quality control and processes to uphold enduring product integrity • Travelled globally to customer sites and summits to promote technology • Maintained regulatory approval through EU Horizon 2020 update • Created relationships with key research partners • Contributing member of Executive Business Team • Chaired EH+S program

Directed pre-IND drug-delivery research through in vivo studies • Launched collaboration with CRO and partners to eliminate need to invest $100ks internally • Contributing member of Business Development Team • Aligned business plan with budget

Directed lead-acid battery research program which was spun off as a Joint Venture • Assembled company’s largest research group and built 3 lab spaces (>$2M equipment) • Established TS+D program to meet external needs with internal research

Formulated and scaled a carbon nanotube battery additive from lab scale to industrial production (>50MT) • Principle inventor on key formulation patents which protected products • Produced customer documentation (SDS, COA, TDS)

Structure-based drug development of inhibitors against the Prion/Amyloid-β interaction believed to result Alzheimer’s Disease neurodegeneration • Guided the lab along a path towards clinical trials/commercialization • Provided biochemical expertise to students and staff • Submitted grants to fund research • Protein Expression/Purification • X-ray/NMR Spectroscopy

Activity-based probe profiling for system-wide proteomic interrogation of drug-dosed mice for ADR detection • Provided data and technical insight for RO1/STTR grants • MS-based protein ID (Agilent/QTRAP 4000 - Certified User, Thermo LTQ) • MS-based peptide quantification in serum (MRM) • In vivo substrate identification for biomarker discovery

General maintenance of the three NMR spectrometers currently available to the Tufts Univesity - Sackler School community (Bruker 300, 500, and 600). Includes liquid nitrogen, liquid helium, and gas refills as well as providing limited aid to those wishing to run spectra.SKILLS = Maintenance of over $1M of Bruker High Resolution Magnets (NMR300/500/600) • On-site aid for novice users/students

NMR and X-Ray based study of two facets of serine protease function: the pKa of Asp102 and the origin of the characteristic low-field 1H-NMR peak. Despite decades of research, the pKa of the acidic member of the catalytic triad has gone undefined, until now. This work is published - See Below.The presence of low-field 1H-NMR resonances in serine protease spectra has been acknowledged for years and have been a crucial component in many method-of-action studies and mechanistic studies. We discovered that the low-field resonances in alpha-lytic protease were due entirely to the presence of autocatalytic degradants formed during lyophilization, a procedure deemed 100% necessary to observe the signals at all. These degradants were identified as 5- and 7-mer peptides which, as poor substrates for alpha, contorted the active site into producing these aberration in a mechanistically important way.SKILLS = Protein expression in bacterial/mammalian-plasmid expression systems • High yield HPLC/FPLC-based protein purification (Akta Purifier w/ IEX, RP, affinity, filtration) • 1D/2D/3D NMR including 1H, 15N, 13C, RDC, HCACO, HCCH-TOCSY • X-Ray Crystallography (crystallization trials, structure refinement, solution = 3QGJ.pdb) • MS-based protease-peptide stability assays (LC/MS, Agilent 1100/Thermo LCQ Duo) • Kinetic parameter determination (Km, Kcat, IC50, Ki) • In vitro inhibition studies with boronic acids, peptide mimetics, and other site-directed inhibitors • Mammalian tissue culture • Lyophilization

Tutoring small to medium sized groups (2-15) of students from a broad range of backgrounds in the first year class's General Biochemistry course. Subjects include basic Michealis-Menton kinetics, reaction pathways, enzyme mechanisms, drug design, drug mechanism of actions, protease-directed cancer therapy.

Large sales of audio/video equipment, handling of bulk orders and special setups, customer education programs, received continual technical education during the 4 months. Exemplary sales recognition for the last two months.