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Paula is an executive leader, independent board member and venture investor with more than 35 years of biopharma industry experience in strategic and operational leadership. She has experience in drug development, global commercialization, manufacturing, new company formation and company building, including founding and leading 2 companies. In addition to a strong focus on rare disease, her career spans a broad range of therapeutic areas including cardiovascular and metabolism, neurology, infectious disease, renal, and transplant and oncology.
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Venture Partner5Am VenturesBoston, Ma, Us -
Chairman Of The BoardEnsoma Oct 2021 - PresentBoston, Ma, Us -
Interim Ceo And Chairman Of The BoardEnsoma Jan 2024 - May 2024Boston, Ma, Us
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Founding Executive ChairmanEnsoma Mar 2020 - Oct 2021Boston, Ma, UsLaunched company from venture seed stage and building out initial strategy, operations and team.
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Venture Partner5Am Ventures Jan 2023 - PresentSan Francisco, California, Us
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Venture Advisor5Am Ventures Mar 2020 - Jan 2023San Francisco, California, Us
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Board Of DirectorsDianthus Therapeutics, Inc. May 2022 - PresentNew York City, New York, UsCommittees: Chair, Compensation Committee; Audit Committee -
Board Of DirectorsRallybio Nov 2020 - PresentNew Haven, Connecticut, UsLead Independent Director, Dec 2023 to presentCommittees: Chair, Compensation Committee -
Board Of DirectorsKyowa Kirin, Inc.- U.S. Sep 2021 - PresentPrinceton, New Jersey, UsCommittees: Chair of Audit, Chair of Compensation -
Strategic Advisory BoardChiesi Usa, Inc. Feb 2021 - PresentCary, North Carolina, Us -
Advisory Board, Department Of Chemical And Biochemical EngineeringTufts University Jan 2005 - PresentMedford, Massachusetts, Us -
Corporate Board Of DirectorsUniqure Jun 2013 - Jun 2024Amsterdam, 1105Bp, NlCommittees: Nomination & Governance; Research and DevelopmentPast: Audit, Compensation, Commercial -
Founding CeoAkcea Therapeutics Jan 2015 - Sep 2019Founding CEO and first employee in 2015. Led the company through its IPO on NASDAQ in 2017, as well as significant growth: employing over 280 staff in 13 countries, 6 drugs in its portfolio with 2 rare disease drug approvals. Akcea launched its first rare disease therapy for hereditary TTR Amyloidosis in global markets in 2018 and its second rare disease therapy in Europe for Familial Chylomicronemia Syndrome in 2019. Akcea’s business model was centered around the patient, working to unite, educate and empower its rare disease patient communities globally
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Senior Vice President And General Manager, Cardiometabolic, Rare Diseases And Strategic AlliancesModerna Therapeutics Jul 2013 - Dec 2014Cambridge, Massachusetts, UsExecutive Committee member of Moderna Therapeutics, pioneering messenger RNA therapeutics. -
Vice President & General Manager, CardiovascularSanofi Genzyme Oct 2009 - Mar 2013Paris, France, FrLed cardiovascular business from early portfolio prioritization of science and new business development opportunities through commercialization. Priorities include P&L accountability, turning around Cholestagel business to profitability, leading development and partnership for Kynamro, a novel antisense technology for a rare genetic disease, through clinical development and regulatory approval, spearheading market development, global launch preparations, pricing and market access. -
Vp & Product General Manager, Transplant/OncologySanofi Genzyme Aug 2008 - Oct 2009Paris, France, FrLed the development and global commercialization of Mozobil, a novel stem cell mobilizer for hematopoietic stem cell transplantation of patients with Multiple Myeloma and Non-Hodgkin’s Lymphoma. Priorities included managing P&L to profitability in first quarter of commercial launch, establishing global market plan, and execution for global launches, pricing, market access, leading team to successful on time approvals in US and Europe and structuring secure manufacturing supply chain.
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Vice President, Global Strategic Marketing, TransplantSanofi Genzyme Aug 2007 - Aug 2008Paris, France, FrDirected the ongoing development of product portfolio for solid organ transplant and bone marrow transplantation, leading commercial plans, revised global pricing strategy and new product development.
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Vice President, Tolevamer Commercial OperationsSanofi Genzyme 2006 - Aug 2007Paris, France, FrLed the development of a novel late stage product for the treatment of Clostridium Difficile Associated Disease through phase III program; established and led team preparing for product approval, commercial launch, and the establishment of a global business. Responsible for P&L and LRP planning as well as new business development evaluations in Infectious Disease.
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Vp, Program Management & Strategic DevelopmentSanofi Genzyme 2003 - 2006Paris, France, FrLed portfolio strategy, alliance management and manufacturing operations. Priorities included evaluation/prioritization of new disease target for internal science and external business development, managing multiple drug development programs and external partnerships from preclinical through commercialization, established secure manufacturing supply chain, managed joint development and commercial partnerships and P&L for Japan and Asia, led business development process and integration of Bone Care International acquisition.
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Senior Director, Renagel Operations, Genzyme RenalSanofi Genzyme 2000 - 2003Paris, France, FrDeveloped and implemented strategy of global manufacturing and product development for oral product, Renagel.
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Director Capital Project Management, Genzyme Global OperationsSanofi Genzyme 1998 - 2000Paris, France, FrLed overall management of facility and manufacturing capital projects, leading a staff of project managers, ensuring project delivery budgets and schedules. Chaired an executive management team chartered with corporate strategic capital appropriations
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Engineering Management (Various Positions)Sanofi Genzyme 1992 - 1998Paris, France, Fr
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Project Engineer/Process EngineerBadger Engineers, Raytheon May 1991 - Aug 1992
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Project Engineer/Process EngineerCarlson Process Company 1989 - 1991
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Cell CultureIntegrated Genetics 1988 - 1989
Paula Soteropoulos Skills
Paula Soteropoulos Education Details
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University Of Virginia Darden School Of BusinessBusiness Administration And General Management -
Tufts UniversityChemical & Biochemical Engineering
Frequently Asked Questions about Paula Soteropoulos
What company does Paula Soteropoulos work for?
Paula Soteropoulos works for 5am Ventures
What is Paula Soteropoulos's role at the current company?
Paula Soteropoulos's current role is Venture Partner.
What is Paula Soteropoulos's email address?
Paula Soteropoulos's email address is ps****@****oma.com
What is Paula Soteropoulos's direct phone number?
Paula Soteropoulos's direct phone number is +161725*****
What schools did Paula Soteropoulos attend?
Paula Soteropoulos attended University Of Virginia Darden School Of Business, Tufts University.
What skills is Paula Soteropoulos known for?
Paula Soteropoulos has skills like Biotechnology, Commercialization, Pharmaceutical Industry, Biopharmaceuticals, Clinical Development, Cross Functional Team Leadership, Life Sciences, Strategy, Oncology, Infectious Diseases, Leadership, Global Marketing.
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