Paul D. Rennert

Paul D. Rennert Email and Phone Number

Acting CEO, President and CSO @ Aleta Biotherapeutics
Natick, MA, US
Paul D. Rennert's Location
Natick, Massachusetts, United States, United States
Paul D. Rennert's Contact Details

Paul D. Rennert work email

Paul D. Rennert personal email

About Paul D. Rennert

I am a top-tier Biotechnology Investigator and Executive with extensive strategic and leadership experience and demonstrated success in bench to IND development of small molecule and biologic drugs for oncology, autoimmunity, chronic inflammation and fibrosis. I have deep experience in therapeutic area analysis and strategic development, opportunity assessment, due diligence, and alignment of research, commercial and clinical strategies. My recent accomplishments include working intensively with CoStim Pharmaceuticals' executive team to prioritize and launch that company's Cancer Immunotherapeutics portfolio. More recently I embedded with X-Chem Inc to create X-Rx Discovery, an asset-centric biotechnology company. As CSO, I built that company from conception to full portfolio execution, including medicinal chemistry, assay development, ADME/DMPK support, efficacy and toxicity assessment. I drove two lead programs, targeting autotaxin and BTK, from hit through lead optimization, and selected lead candidates for IND enablement. More broadly, I have consulted extensively across the academic, biotechnology and venture capital environments. My contributions to corporate development include comprehensive research planning, identifying funding sources, evaluating the therapeutic rationale for pathways targeted in specific diseases (oncology, inflammation, autoimmunity, metabolic disease, cardiovascular disease, asthma and many others), review of specific molecular targets, and identifying key academic and corporate partners for specific programs. My ability to work so broadly across the bio-pharmaceutical landscape is grounded in my long and highly successful career in the industry, notably at Biogen Idec Inc.My CV may be found at www.sugarconebiotech.com

Paul D. Rennert's Current Company Details
Aleta Biotherapeutics

Aleta Biotherapeutics

View
Acting CEO, President and CSO
Natick, MA, US
Website:
aletabio.com
Employees:
6
Paul D. Rennert Work Experience Details
  • Aleta Biotherapeutics
    Acting Ceo, President And Cso
    Aleta Biotherapeutics
    Natick, Ma, Us
  • Aleta Biotherapeutics
    Acting Ceo, President & Cso
    Aleta Biotherapeutics Jan 2022 - Present
    Natick, Ma, Us
  • Aleta Biotherapeutics
    President & Cso
    Aleta Biotherapeutics Jan 2016 - Feb 2022
    Natick, Ma, Us
  • Sugarcone Biotech Consultants Llc
    Founder & Principal
    Sugarcone Biotech Consultants Llc 2012 - 2016
  • X-Rx Discovery
    Chief Scientific Officer/Executive Consultant
    X-Rx Discovery Sep 2012 - Jan 2014
    X-Rx Discovery develops novel therapeutics for oncology, inflammatory and metabolic diseases. As CSO I created and executed preclinical development campaigns for a suite of stunning NCEs directed to novel targets. Critical goals include developing and managing the pipeline, building a network of collaborations that will help assess therapeutic activity, driving compound development through lead optimization and validation using in vitro, in vivo and toxicology assays and models, and building a compelling vision for the therapeutic use of X-Rx Discovery's novel drugs.
  • Biogen Idec
    Principal Scientist
    Biogen Idec May 1995 - May 2012
    Cambridge, Ma, Us
    Summary. Strategic, program, and project leadership, with broad responsibility for the analysis and advancement of therapeutic small molecule and biological candidate molecules, including discovery, validation and IND-enabling studies. Managed programs across Discovery Research, Medicinal and Protein Chemistry, Pre-Clinical, Clinical and Commercial operations to deliver critical analyses, linked to timelines and milestones, to enable efficient and informed program development.Recent Positions and Responsibilities.- Head, Translational ImmunoBiology Modeling- Principal Investigator, Immunobiology and Immunopharmacology - Member, Immunobiology and Rheumatology Strategic Leadership- Co-Lead, Fibrosis Strategic Review- Co-Lead, Lupus and Lupus Nephritis Strategic Area Review- Member Scientific Diligence for Biogen Idec Corporate Strategy - Lead R&D scientist, Tysabritm post-registrational studies and JC Virus mitigation - Head, Cardiovascular Inflammation Discovery
  • Repligen Inc
    Associate Scientist, Departments Of Molecular Biology And Molecular Immunology
    Repligen Inc 1986 - 1995
    Waltham, Ma, Us
    Immunology Staff Scientist: T Cell Costimulation- Led structure/function analyses of CD28 ligands B7-1 and B7-2- Cloned and patented a novel form of CTLA4-Ig fusion protein for use in transplantation- Cloned and patented novel T cell activation proteins, fusion proteins and antibodies- Managed core facility for DNA sequencing and oligonucleotide synthesis

Paul D. Rennert Skills

Immunology Drug Development Biotechnology Assay Development Drug Discovery In Vitro Clinical Development Pharmacology In Vivo Biopharmaceuticals Inflammation Monoclonal Antibodies Protein Chemistry Oncology Lifesciences Cell Biologics Small Molecules Cardiovascular Disease Ind Technology Transfer Biochemistry Cell Biology Due Diligence Asthma Antibodies Rheumatology Validation Translational Research Clinical Trials Autoimmunity Cancer Technology Evaluation Stem Cells Rheumatoid Arthritis Business Development Autoimmune Diseases Translational Medicine Biomarkers Immunoassays R&d Toxicology Clinical Research Biomarker Discovery Lead Change Metabolism Elisa Signal Transduction High Throughput Screening Lupus

Paul D. Rennert Education Details

  • University Of Vermont
    University Of Vermont
    Biology
  • Colby College
    Colby College
    Philosophy

Frequently Asked Questions about Paul D. Rennert

What company does Paul D. Rennert work for?

Paul D. Rennert works for Aleta Biotherapeutics

What is Paul D. Rennert's role at the current company?

Paul D. Rennert's current role is Acting CEO, President and CSO.

What is Paul D. Rennert's email address?

Paul D. Rennert's email address is pa****@****dec.com

What is Paul D. Rennert's direct phone number?

Paul D. Rennert's direct phone number is +161767*****

What schools did Paul D. Rennert attend?

Paul D. Rennert attended University Of Vermont, Colby College.

What skills is Paul D. Rennert known for?

Paul D. Rennert has skills like Immunology, Drug Development, Biotechnology, Assay Development, Drug Discovery, In Vitro, Clinical Development, Pharmacology, In Vivo, Biopharmaceuticals, Inflammation, Monoclonal Antibodies.

Who are Paul D. Rennert's colleagues?

Paul D. Rennert's colleagues are Kathryn Matt.

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