Paul D. Rennert Email and Phone Number
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I am a top-tier Biotechnology Investigator and Executive with extensive strategic and leadership experience and demonstrated success in bench to IND development of small molecule and biologic drugs for oncology, autoimmunity, chronic inflammation and fibrosis. I have deep experience in therapeutic area analysis and strategic development, opportunity assessment, due diligence, and alignment of research, commercial and clinical strategies. My recent accomplishments include working intensively with CoStim Pharmaceuticals' executive team to prioritize and launch that company's Cancer Immunotherapeutics portfolio. More recently I embedded with X-Chem Inc to create X-Rx Discovery, an asset-centric biotechnology company. As CSO, I built that company from conception to full portfolio execution, including medicinal chemistry, assay development, ADME/DMPK support, efficacy and toxicity assessment. I drove two lead programs, targeting autotaxin and BTK, from hit through lead optimization, and selected lead candidates for IND enablement. More broadly, I have consulted extensively across the academic, biotechnology and venture capital environments. My contributions to corporate development include comprehensive research planning, identifying funding sources, evaluating the therapeutic rationale for pathways targeted in specific diseases (oncology, inflammation, autoimmunity, metabolic disease, cardiovascular disease, asthma and many others), review of specific molecular targets, and identifying key academic and corporate partners for specific programs. My ability to work so broadly across the bio-pharmaceutical landscape is grounded in my long and highly successful career in the industry, notably at Biogen Idec Inc.My CV may be found at www.sugarconebiotech.com
Aleta Biotherapeutics
View- Website:
- aletabio.com
- Employees:
- 6
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Acting Ceo, President And CsoAleta BiotherapeuticsNatick, Ma, Us -
Acting Ceo, President & CsoAleta Biotherapeutics Jan 2022 - PresentNatick, Ma, Us -
President & CsoAleta Biotherapeutics Jan 2016 - Feb 2022Natick, Ma, Us -
Founder & PrincipalSugarcone Biotech Consultants Llc 2012 - 2016
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Chief Scientific Officer/Executive ConsultantX-Rx Discovery Sep 2012 - Jan 2014X-Rx Discovery develops novel therapeutics for oncology, inflammatory and metabolic diseases. As CSO I created and executed preclinical development campaigns for a suite of stunning NCEs directed to novel targets. Critical goals include developing and managing the pipeline, building a network of collaborations that will help assess therapeutic activity, driving compound development through lead optimization and validation using in vitro, in vivo and toxicology assays and models, and building a compelling vision for the therapeutic use of X-Rx Discovery's novel drugs.
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Principal ScientistBiogen Idec May 1995 - May 2012Cambridge, Ma, UsSummary. Strategic, program, and project leadership, with broad responsibility for the analysis and advancement of therapeutic small molecule and biological candidate molecules, including discovery, validation and IND-enabling studies. Managed programs across Discovery Research, Medicinal and Protein Chemistry, Pre-Clinical, Clinical and Commercial operations to deliver critical analyses, linked to timelines and milestones, to enable efficient and informed program development.Recent Positions and Responsibilities.- Head, Translational ImmunoBiology Modeling- Principal Investigator, Immunobiology and Immunopharmacology - Member, Immunobiology and Rheumatology Strategic Leadership- Co-Lead, Fibrosis Strategic Review- Co-Lead, Lupus and Lupus Nephritis Strategic Area Review- Member Scientific Diligence for Biogen Idec Corporate Strategy - Lead R&D scientist, Tysabritm post-registrational studies and JC Virus mitigation - Head, Cardiovascular Inflammation Discovery -
Associate Scientist, Departments Of Molecular Biology And Molecular ImmunologyRepligen Inc 1986 - 1995Waltham, Ma, UsImmunology Staff Scientist: T Cell Costimulation- Led structure/function analyses of CD28 ligands B7-1 and B7-2- Cloned and patented a novel form of CTLA4-Ig fusion protein for use in transplantation- Cloned and patented novel T cell activation proteins, fusion proteins and antibodies- Managed core facility for DNA sequencing and oligonucleotide synthesis
Paul D. Rennert Skills
Paul D. Rennert Education Details
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University Of VermontBiology -
Colby CollegePhilosophy
Frequently Asked Questions about Paul D. Rennert
What company does Paul D. Rennert work for?
Paul D. Rennert works for Aleta Biotherapeutics
What is Paul D. Rennert's role at the current company?
Paul D. Rennert's current role is Acting CEO, President and CSO.
What is Paul D. Rennert's email address?
Paul D. Rennert's email address is pa****@****dec.com
What is Paul D. Rennert's direct phone number?
Paul D. Rennert's direct phone number is +161767*****
What schools did Paul D. Rennert attend?
Paul D. Rennert attended University Of Vermont, Colby College.
What skills is Paul D. Rennert known for?
Paul D. Rennert has skills like Immunology, Drug Development, Biotechnology, Assay Development, Drug Discovery, In Vitro, Clinical Development, Pharmacology, In Vivo, Biopharmaceuticals, Inflammation, Monoclonal Antibodies.
Who are Paul D. Rennert's colleagues?
Paul D. Rennert's colleagues are Kathryn Matt.
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