Dr. Lyster is a contractor at the NIH National Institute of Biomedical Imaging and Bioengineering (NIBIB). He was program manager in the National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) Division of Biomedical Technology, Bioinformatics, and Computational Biology. Dr. Lyster's career incluses a broad focus on computational physics, computational drug discovery, bioinformatics, climate research, and high-performance computing and communcations. He served as the lead of the NIGMS National Centers for Systems Biology (NCSB) program and was co-lead of the Big Data (BD2K) Centers of Excellence in Big Data Science. He was formerly the Deputy Director of the National Coordination Office (NCO) of the White House Office of Science and Technology Policy (OSTP) Networking and Information Technology Research and Development (NITRD) program. Before that he was a program director at the National Institute of Biomedical Imaging and Bioengineering and a review officer at the NIH Center for Scientific Review. Prior to joining NIH, Dr. Lyster worked at the Jet Propulsion Laboratory in Pasadena, California, where he laid the groundwork for some of the scientific applications of the Federal High Performance Computing and Communications (HPCC) initiative. He then became Principal Investigator in the HPCC program at NASA Goddard Space Flight Center at the University of Maryland. As such, he led the effort to use massive computing power to improve data collection for weather and climate models. Dr. Lyster received his Ph.D. in Physics and Computational Science from Cornell University. His thesis topic was computational plasma (nuclear) physics. His expertise is in computational science and technology in a range of domain areas that have societal relevance: nuclear energy research, climate and weather research, networking and communications, and biomedicine.