Paul Fishbein Email & Phone Number

Cherry Hill, Nj, Us

Cherry Hill, Nj

Responsible for research and development of new products, new processing technologies, providing technical direction for cosmeceuticals, acrylic polymer containing cosmetics, dental products. Responsible for patent applications and prosecutions for all Keystone patents.

PROCESS CHEMISTLooking for opportunities as bench chemist in process chemistry or in managerial / supervisory role in chemical process R&D in pharmaceutical, biotech, agrochemical, or chemical company that utilizes proven leadership, complex problem solving, organizational, and communication experience to improve existing processes or bring new products to market in rapid and cost efficient manner.CONSULTANTHelping big and small business, especially biotech companies, manage their interactions with CMOs and CROs as well as with process chemistry in general. Accomplishments Successfully consulting for a start-up biotech company with the management of a CMO and technical issues that arise. Also, successfully consulting for an acrylic polymer company.Skills Used Project management, synthetic organic chemistry, process chemistry. patents / intellectual propertyINTELLECTUAL PROPERTYAlso considering opportunities to serve as Patent Chemist, Technical Advisor, Scientific Advisor, or Patent Agent (once licensed), primarily for pharmaceutical, chemical, and biotech intellectual property (patents).Recent Experiences:• Consultant in chemical process R&D and scale-up for a bioconjugate biotech startup (ongoing).• Private tutor for multiple students for college-level chemistry.• Reviewer for American Chemical Society Petroleum Research Fund grant applications and Organic Process Research & Development article submissions.• Seminar presenter at Rowan University, Stockton College, and SJ ACS section on chemical process R&D and statistical optimization techniques.• Technical Specialist for solo practice attorney.• Advisor in Intellectual Property matters for pro se inventors.• Project manager for Networked Expert Workforce.

Cherry Hill, Nj

Oversee and evaluate collections of prior art for clients looking to invalidate patent claims. Work closely with the client to refine the search parameters given to the prior art researchers so they can find the most appropriate references. Take ownership of the technical review and manage it from start through completion of the study.

Glassboro, Nj

Teaching an Advanced Special Topics course of my own design in Chemical Process Research and Development with an emphasis on Active Pharmaceutical Ingredients.

Responsible for quickly developing robust, reliable, financially sound chemical processes to make APIs both as a lab chemist and a project leader. This also included certain aspects of locating raw material vendors, financial analysis, and regulatory / compliance documentation. Participated in and led multifunctional teams for developing such processes. Assumed ownership for entire process from inception through implementation and trouble-shooting. Responsible for 19 different processes consisting of multiple steps, many of which were run simultaneously in a plant.JM Pharma manufactures bulk generic APIs many of which contain precious metals or are controlled substances.Highlights:• Through managing multiple teams and personal bench work, devised, developed, and implemented on time new process to make amphetamines with cost savings of 60%. Patent application has been filed.This work won the 2008 Innovation Award given by the CEO of Johnson Matthey LLC.• Introduced new graphical method of communicating project status to upper level management. This technique was then to be implemented division wide.• Devised, developed, and implemented new hydrogenolysis that was safer, faster, less expensive, and more sustainable to make synthetic opiate.• Developed and implemented process to make hydroxycarboxylate salt used to treat fibromyalgia and narcolepsy. Used and documented Failure Mode Effects Analysis (FMEA) required by FDA Quality by Design (QbD) initiative.• Developed and implemented method to control particle size of Methylphenidate Hydrochloride.• Devised synthesis for Phytonadione.• Devised synthesis for nucleoside antiviral.

Responsible for quickly developing robust, reliable, financially sound chemical processes to make APIs. This also included certain aspects of locating raw material vendors and regulatory / compliance documentation. Participated in and led multifunctional teams for developing such processes. Assumed ownership for entire process from inception through implementation and trouble-shooting.Highlights:• Assembled, led, and worked along side multifunctional team to produce Tetrahydrocannabinol in GMP Kilo Lab. Accomplished ahead of very aggressive deadline, which resulted in $1.5 M milestone payment from customer.• Led team, at bench and in manufacturing, to solve problem of decreasing yields of synthetic opiate intermediate resulting in 200% increase over baseline.• Supervised Reference Standard Production Chemist and another bench chemist. Conducted annual performance reviews with each one.• Devised most of reference standard syntheses. • Gave site-wide seminar on statistical process control analysis resulting in 50% decrease of Manufacturing Incident Reports (MIRs).• Devised method and supervised chemist to make hydrochloride salt of previously unisolated highly potent synthetic opiate analgesic. Patent application is pending.

Responsible for quickly developing robust, reliable, financially sound chemical processes to make APIs. This also included certain aspects of regulatory / compliance documentation. Participated in multifunctional teams for developing such processes. Assumed ownership for entire process from inception through implementation and trouble-shooting.Highlights:• Invented and developed process making previously unknown dibasic salt of amine stimulant used for treating ADD.

Responsible for quickly developing robust, reliable, financially sound chemical processes to make APIs. This included certain aspects of regulatory / compliance documentation. Participated in multifunctional teams for developing such processes. Assumed ownership for entire process from inception through implementation and trouble-shooting.Highlights:• In only 3 weeks, developed hydrogenation process for pyridine intermediate that was faster, safer, less expensive, more sustainable, more reliable, and more robust than industry standard. Output was increased by 15% with cost savings of $500,000/yr. Devised plans for and supervised several teams to conduct experiments in support of Pre-Approval Inspection. Personally documented all work in six reports which were presented to FDA and resulted in approval.For this work, received largest non-management bonus ever awarded.• Managed GMP Kilo Lab and Supervisor. Conducted annual performance reviews with Lab Supervisor.• Developed process to make immediate precursor to Difenoxin Hydrochloride.• Optimized process to freebase Codeine in nearly quantitative yield.• Developed operable process to make Codeine Methyl Ether.• Site administrator for STN and SciFinder databases.

Responsible for design, synthesis and government approval for manufacture of various agrochemical, pharmaceutical, and cleaning product intermediates at both lab and pilot plant scale.Highlights:• Received a DuPont 1992 Scientific Accomplishment Award for work in using fluorocarbon blood substitute in production of hydrogen peroxide.

Post doc in Chemical Process Research concentrating on steroids.

Postdoctoral Fellow, Organic Synthesis Of Mitomycin C Derivatives

With Harold Kohn: Synthesis of less toxic and more selective derivatives of mitomycin C, a clinically used cancer chemotheraputic drug..

Ph.D., Organic Chemistry

With Harold Moore: Doctoral Thesis - Syntheses of Cyanoketenes and Synthetic and Mechanistic Studies of their Reactions with Alkenes.

B.S., Chemistry

Activities and Societies: Member of the local Student Affliate Section of the American Chemical Society.With Leo Abood and Andrew Kende.

Hs Diploma