As PSC's Scientific Director, I direct PSC’s research and research support teams, including Biomedical Applications, AI & Big Data, and User Support for Scientific Applications. In my own work, I am focused on architecting, building, and supporting cutting-edge research resources that provide the means to overcome difficult scientific problems. Current projects include building and supporting the flexible hybrid cloud microservices architecture supporting the NIH Human Biomolecular Atlas Program (HuBMAP) and Cellular Senescence Network (SenNet) Program and integrating these resources with the NIH Common Fund Data Ecosystem (CFDE). I also lead the NIH Anton project at PSC, in collaboration with D. E. Shaw Research. I previously served as co-PI of the NSF XSEDE project. In these roles, I work closely with PSC’s leadership team to accomplish our mission to apply advanced computing to enable discoveries that benefit the world.

In this role I oversaw PSC’s Biomedical Applications and Public Health Applications Groups and directed PSC's strategic efforts across the life sciences.

My responsibilities included the creation of novel ideas, concepts, methods, algorithms and codes; implementing these in an optimal fashion on leading-edge scalable supercomputing systems; helping to write winning grant proposals to fund these research activities; and planning and executing outreach activities to publish and promote the scientific and technological progress that is being achieved. I helped set the direction of PSC's endeavors within my scientific focus domains (computational biology, biophysics, and bioinformatics) and also lead collaborative projects within XSEDE (the NSF-funded national cyberinfrastructure for open scientific research) to enable large-scale computational research both inside and outside of my scientific domains. Within XSEDE, I also served on the leadership team for the Campus Champions program to help promote the effective use of research cyberinfrastructure seamlessly from the campus to the national level.

For my Ph.D. thesis I researched biologically important lipid and protein systems using novel, large-scale molecular dynamics simulations on supercomputers.