Pierre M. Email & Phone Number

Paris Area, France

➤ Data Science consulting for Bristol Myers Squibb on a machine learning classification project predicting patients’ retention to a specific drug. This project was featured in the American College of Rheumatology (ACR) and AI for Health conferences in November 2020.➤ Exploration and processing of clinicaltrials.org database with NLP techniques and advanced analysis of textual data. This innovative project was eligible to the French Tax Credit Research.➤ Development and teaching of a Python training program. Also performed Data Science vulgarization and initiation for collaborators and clients

Greater Boston Area

6 months Master's internship in the Perrimon Lab at Harvard Medical School, Genetics Department.Subject :⇒ Machine Learning predictions of CRISPR/Cas9 on-target efficiency in Drosophila melanogasterThis project aimed to provide the Drosophila RNAi Screening Center (DRSC) with an accurate CRISPR sgRNA efficiency scoring tool in order to improve the sgRNA design pipeline. I used Machine Learning algorithms to model the efficiency of sgRNAs targeting essential genes, based on their characteristics, in a D.mel genome-wide pooled CRISPR screen. The Machine Learning models identified were implemented in a command-line tool with which single or batch sgRNA efficiency predictions can be made from the raw sgRNA sequence (see GitHub link).Skills :➤ Programming and Machine Learning in Python and R➤ CRISPR/Cas9 genetic engineering, molecular genetics and genomics➤ Scientific literature review, autonomy, public speaking, GitHub version control

Paris Area, France

Two months internship in the Laboratory of Theoretical Physics and Condensed Matter.(LPTMC - UMR CNRS 7600)Subject :⇒ Expressed genes domain identification of different cell types by high-throughput data analysis.I helped in the development of a machine learning pipeline to infer the best preprocessing method to detect expression signals in complex datasets. The datasets' cell types are then to be clusterized into large cellular groups (brain, blood, gut, etc...) according to their presumed expression pattern (unsupervised machine learning).Skills :➤ Python programming (Jupyter, NumPy, pandas, Scikit-Learn, Matplotlib etc...)➤ Handling very large datasets (over 250Gb of RAM)➤ Data cleaning, visualization and processing (.bed/.hdf5, large arrays, sparse matrix etc...)

Paris Area, France

Internship in the Atelier de BioInformatique (ABI - UMR 7205) in the National Museum of Natural History.Subject :⇒ Comparative Genomics characterization of Salmonella enterica serovar Dublin strains implicated in osteo-articular infections.Three pathogenic bacterial strains were harvested from hip prosthesis infections. The goals were to used bioinformatics and comparative genomics tools to :➤ Develop of a Multi-Locus Sequence Typing script (Python) to confirm the strains' serotype (Salmonella enterica serovar Dublin)➤ Identify genomic rearrangements (recombination, viral insertion, genomic reduction) with MAUVE (Multiple Genome Alignment) and/or ACT (Artemis Comparison Tool)➤ Establish the phylogeny analysis of the strains➤ Identify specific gene/region that would explain the enhanced colonization/virulence of the strains

Gif-Sur-Yvette, France

Two months internship in the Growth and Metabolism of Drosophila team of the Institute of Integrative Biology of the Cell (I2BC - UMR 9198)Subject :⇒ Characterization of lipid metabolism and genetics of Drosophila.➤ Genetic markers recognition in larvae and adult Drosophila to identify different genotypes➤ Crossbreedings techniques and drosophila stocks management➤ Spectrophotometry analysis of the lipid content of several drosophila genotypes at different larvae stages.

Paris, Saint-Quentin-En-Yvelines And Others

Part-time English teaching/baby-sitting or summer jobs in different places to finance my studies. These experiences helped me acquire many organizational and human skills :English Teacher | ANACOURS | Paris, Elancourt - France (2015-2016)Private English lessons for high-school students.➤ Pedagogy➤ Planning➤ TrackingReceptionist & General Services Officer | SWAROVSKI International | Paris - France (Summer 2016)Reception, inventory management, bookings in French and English.➤ Organization➤ TeamworkCertificated Animator | Malakoff Médéric & day care centers | Saint-Quentin-en-Yvelines, Elancourt - France (Summers 2011 - 2014)Responsibility of children (4-12yo), development of activities, various administrative tasks.➤ Leadership & Team management➤ Pedagogy & Education➤ Planning➤ Creativity

Master'S Degree, Bioinformatics, 3.5 Gpa

Paris-Sud University is one of the largest and most renowned French university, particularly in science and mathematics. ▷ The University.

Bachelor'S Degree, Molecular Genetics

UVSQ is the leading university in France in terms of student success at the bachelor level and ranks third for the number of apprentices.