💡 Research Focus:Working towards a groundbreaking therapeutic approach to improve patient well-being by addressing the pathogenesis of Parkinson's Disease (PD). Our research centers on nanotechnology-driven drug delivery of lysosomal proteins to the brain, through intranasal administration, to tackle the Autophagy and Lysosomal Dysfunction of neurons. 🤝 Collaborative Environment:Thriving under the collaborative framework of the Autophagy and Lysosomal Dysfunction Group, I work closely with interdisciplinary teams to bridge fundamental research and therapeutic applications.🎯 Impact:Driven by a passion for improving patients’ quality of life, my work aims to develop innovative, real-world therapies that address the root causes of Parkinson’s disease and other neurodegenerative conditions.

🌟Research Highlights🌟📊 Comprehensive Analysis of Cellular Mechanisms: Conducted detailed studies of lysosomal enzyme activities, protein expression levels, and lysosomal mass to understand their roles in cellular homeostasis and disease pathology. Explored autophagic flux to uncover its disruptions in disease states. 🔬 Cutting-Edge Experimental Techniques: Mastered methodologies such as Western Blot quantification, antibody validation, and functional assays to evaluate lysosomal, autophagic, and endosomal functions with precision. Designed experiments to assess mitochondrial morphology and vesicular delivery mechanisms towards lysosomes.🧬 Genomic insight: Investigated the roles of specific genes contributing to lysosomal and autophagic dysfunction, revealing potential molecular targets for personalized therapies. 🌟Key Findings🌟Identified noteworthy impairments in lysosomal/autophagy function in patients with idiopathic parkinsonism and lysomal genes alterations.Highlighted critical alterations in vesicular trafficking, mitochondrial structure, and autophagic dynamics, unveiling disparities between patients and healthy controls.🌐Why This MattersThe outcomes of my research emphasize the pivotal role of lysosomal and autophagic pathways in disease progression. By combining rigorous methodologies with a focus on translational relevance, I contribute to bridging the gap between fundamental science and therapeutic application.📈What I kept polishingTechnical Expertise: Proficient in advanced molecular biology techniques, data analysis, and experimental design.Collaborative Mindset: Thrived in interdisciplinary environments, working alongside diverse teams of scientists and clinicians.Problem-Solving Skills: Adept at tackling complex biological questions and translating findings into actionable insights.Passion for Impact: Committed to bridging the gap between fundamental research and real-world therapeutic applications.

🌟Project Overview🌟I worked on a research project focused on chronic liver diseases, particularly Non-Alcoholic Fatty Liver Disease (NAFLD). My role involved characterizing an animal model for NAFLD and evaluating the therapeutic effects of a drug delivered through nanoparticles targeted to specific liver cells.🌟Key Responsibilities🌟🐭Model Development & 💉Drug Administration: Assisted in validating a diet-induced NAFLD animal model, and administered nanoparticle-based therapeutics targeting liver endothelial cells (LSEC).🔬Molecular & Cellular Analysis: Conducted experiments on protein extraction, quantification, and gene expression analysis using PCR, Western blotting, and immunohistochemistry.💊Simvastatin Evaluation: Investigated the impact of simvastatin on liver cells, exploring its potential as a treatment for NAFLD. 🌟Key Findings🌟📊Identified significant changes in protein and gene expression linked to liver function in the animal model, eventually reverted through simvastatin administration.⚖Demonstrated the therapeutic effects of simvastatin on liver endothelial cells.The research provided valuable insights into chronic liver diseases and the use of nanoparticle-based drug delivery systems. 🌱💡🌟Skills Developed 🌟🛠️ Molecular Biology Techniques: Gained hands-on experience with protein analysis, gene expression, and immunohistochemistry.📈Data Analysis: Strengthened my skills in analyzing complex data and interpreting scientific results.🐾⚖️ Bioethics & Animal Welfare: Deepened my understanding of ethical research practices and the importance of ensuring animal welfare throughout the project. 🌟Looking Ahead 🌟🚀This experience has fueled my passion for biomedical research and pharmaceutical development. I’m excited to bring my skills and knowledge to future roles and contribute to scientific advancements in these fields.

As a Student Representative, I actively participated in collaborative meetings, which helped me develop a strong teamwork ethic, negotiation skills, and a proactive approach to problem-solving.🌟Key Responsibilities🌟 📝Evaluation Standards Review: Led efforts to assess and conceptualize modifications to the evaluation standards ("Normativa de Evaluación de la Facultad de Biociencias") to ensure they reflect current students' academic needs. 📊 Collaboration & Negotiation: Worked alongside faculty, students, and administrators to create innovative solutions, promoting positive change and efficient communication. 🌟Skills Developed 🌟🗣️Public Speaking & Leadership: Gained confidence in leading discussions and presenting ideas to diverse groups, enhancing my public speaking and leadership skills.💬Problem-Solving & Innovation: Contributed to innovative solutions that improved academic standards and addressed student needs. 🤝Negotiation & Conflict Resolution: Honed my ability to mediate and negotiate effectively, fostering collaboration between different stakeholders.🌟Impact & Takeaways 🌟🌍 This role allowed me to grow as a proactive suporter with a keen eye for innovation and an ability to effectively communicate with diverse audiences.