Pranav Patel

Pranav Patel Email and Phone Number

Collaborative Professor @ University of South Florida
Tampa, FL, US
Pranav Patel's Location
Tampa, Florida, United States, United States
Pranav Patel's Contact Details

Pranav Patel work email

Pranav Patel personal email

About Pranav Patel

High performing adept achiever with over 23 years of experience guiding pharmaceutical and biotech organizations through ongoing transformation, team building and growth. Adept scientist and leader with technical expertise in the field of medicinal, natural product, new drug discovers as well as generic drug programs including pre-clinical studies.SELECTED PUBLICATIONS •" Two Potent OXE-R Antagonists: Assignment of Stereochemistry" Pranav Patel, C. Reddy, V. Gore, S. Chourey, Qiuji Ye, Y. P. O, S. Gravel, William S. Powell, and J. Rokach: Med. Chem. Lett.,• "Inhibition of 5-Oxo-6,8,11,14-eicosatetraenoic Acid-Induced Activation of Neutrophils and Eosinophils by Novel Indole OXE Receptor Antagonists". J. Med. Chem., 2014, 57 (2), pp 364• “C20-trifluoro-5-oxo-ETE: A metabolically stable 5-oxo-ETE derivative”. Pranav Patel, Vivek Gore, William S. Powell and Joshua Rokach. BMCL, (2011)• “5-oxo-15-HETE: Total synthesis and bioactivity”. Pranav Patel, Jaganmohan Anumolu, William S. Powell and Joshua Rokach. BMCL,(2011)• “Substrate selectivity of 5-hydroxyeicosanoid dehydrogenase and its inhibition by 5-hydroxy- Delta 6-long chain fatty acids”. Pranav Patel, C. Cossette, J. R A, Karl- Rudolf Erlemann, Gail E. Grant, Rokach, & Powell. JPET (2009)• “Enantio and Stereospecific Syntheses of 15(R)-Me-PGD2, a Potent and Selective DP2-Receptor Agonist”. Pranav Patel, Gue-Jae Lee, S. Kim, G. Grant, Powell & Rokach, The Journal of Organic Chemistry (2008)• "Human Neutrophils Convert The Sebum-Derived Polyunsaturated Fatty Acid Sebaleic Acid To A Potent Granulocyte Chemoattractant". Chantal Cossette, Pranav Patel. The Journal of Biological Chemistry (2008)• "Structural requirements for activation of the 5-oxo-ETE receptor: Identification of a Mead Acid metabolite with potent agonist activity". Pranav Patel, Chantal Cossette, J R A, S. Gravel, Alain Lesimple, Orval A. Mamer, J Rokach, &. Powell. JPET (2008)Specialties: Organic Natural Product,Medicinal Chemistry, generic and new drug development,, Nanoformulation, Cannabinoids etc.

Pranav Patel's Current Company Details
University of South Florida

University Of South Florida

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Collaborative Professor
Tampa, FL, US
Pranav Patel Work Experience Details
  • University Of South Florida
    Collaborative Professor
    University Of South Florida
    Tampa, Fl, Us
  • Sgn Nanopharma Inc
    Vice President
    Sgn Nanopharma Inc Jan 2019 - Present
    Tampa, Florida, Us
    • Successfully Validated and commercialized lipid nanoformulation for the treatment of dry eye disease (DED) under brand name EVOLVE.• Successfully developed lipid-based nano-formulations for understanding the Effects of cannabinoid formulations on GFAP expression in human astrocytes for the treatment of traumatic brain injury. • Human Skin penetration studies using Franz Diffusion cell system. Mouse brain extraction studies for nose to brain drug delivery, etc • Researched and Developed generic drugs for ANDA as well as 505b(2) filings to FDA. • Novel drug delivery developed using lipid nanoparticles for the treatment of neurodegenerative diseases using Nose to Brain delivery system for delivering CBD and THC to brain. • Human Eye Cornea penetration/binding studies using Franz Diffusion cell system using Nanoformulations
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  • Sgn Nanopharma Inc
    Director - R&D
    Sgn Nanopharma Inc Feb 2017 - Dec 2018
    Tampa, Florida, Us
    SGN NanoPharma is a cutting edge, clinical-stage, revenue generating, nanotherapeutics company that combines proprietary nanotechnologies (Micellar Nanoparticles, MNP's) with structural biology to generate superior medicines. WWW.SGN.BIO and CBELLANATURALS.COM1. Formulate numerous STABLE Cannabinoid nanoformulations such as THC/CBD Nano lotions and tinctures to generate ophthalmic, neural and transdermal formulations to address large unmet medical needs using cGMP/GLP/QbD/ICH/FDA/RA/QC/QA guidelines2. Successfully lead, executed and commercialized lipid MNP nano formulation, prescription drug, EVOLVE. (Approximately 325000 vials sold commercially, 12% increase YOY)3. Reformulate under-performing FDA approved drugs that are sub-optimal due to poor water solubility and low bio-availability.4. Nose to Brain drug delivery development for treatment of neurodegenerative diseases such as Autism, Alzheimer's, Parkinson's etc. 5. Mouse model for development of nose to brain delivery.6. Micellar Nanoparticle Nanoformulation Development for the Treatment of Traumatic Brain Injury7. Skin as well as eye cornea penetration studies of MNP nanoformulations8. Developed Nano as well as oil formulations of Minoxidil (hair growth) with double retention and same penetration when compared to Rogaine (TM)9. DEA registration and approval10. Skin care products, Anti-aging nanoformulation development
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  • University Of South Florida
    Collaborative Professor, Department Of Molecular Medicine
    University Of South Florida Feb 2019 - Present
    Tampa, Florida, Us
    Mentor USF students in research projects including thesis defense and presentations. Participate in teaching residents and medical students and/or in other educational and research activities. Participate in teaching courses (introduction to biotechnology, BSC6436) residents and USF students and/or in other educational and research activities as well as career development guidance.
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  • University Of South Florida
    Assistant Professor (Affiliate) : Department Of Pharmaceutical Science
    University Of South Florida Feb 2019 - Present
    Tampa, Florida, Us
    Guest speaker in the Graduate Program Seminar, Taneja College of Pharmacy Graduate Program (TCOP) and the USF Center for Research and Education in Nano bioengineeringIndustry Advisory Council (IAC), Founding Committee Member, University of South Florida
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  • Inventys Research Company Pvt Ltd
    Chief Scientific Officer
    Inventys Research Company Pvt Ltd Jan 2015 - Dec 2016
    Mumbai, Maharashtra, In
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  • Navinta Llc
    Director (Chemical Research & Development)
    Navinta Llc Sep 2011 - Dec 2014
    Generic Drug Development Program (R & D, API, cGMP, Validation, Production, DMF)•API research & development, scale-up (literature search, synthetic routes, non-infringement, feasibility, stability studies, degradation/process impurities identification as well as synthesis)•Lab/plant validation batches, stability studies, in-depth interaction with analytical research, QC, and QA department for speedy progress of projects.•Method development/validation, SOP, TTD & PDR reports, cGMP, QbD, cleaning validation, cleaning protocol, stability protocol, STP, Spec. etc,.•DMF and ANDA documentation/filings.
  • Florida Institute Of Technology
    Research Associate
    Florida Institute Of Technology Dec 2008 - Aug 2011
    Melbourne, Florida, Us
    Design and synthesis of novel prostaglandin derivatives for the treatment of various inflammatory diseases including IOP.Designed and developed the first total synthesis of EPA derived isoprostanes and identified them in human urine to develop them as markers of oxidative stress. Designed and synthesized small molecules as 5-oxo-ETE antagonist.
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  • Florida Institute Of Technology
    Research Assistant
    Florida Institute Of Technology Aug 2003 - Nov 2008
    Melbourne, Florida, Us
    Designed and developed the first total synthesis of 15(R)-Me-PGD2, a potent DP2-receptor agonist.Discovered a novel methodology for the selective deprotection of silyl groups.Synthesized sebaleic acid and its metabolites.Successfully executed the project on the design and synthesis of Affinity Chromatography ligands used for the isolation and purification of the enzyme 5-HEDH. Designed and developed novel synthetic route to an all-syn Corey lactone synthon used for the synthesis of all-syn isoprostanes/ neuroprostanes. Designed and synthesized analogs of 5-oxo-ETE and Mead Acid Metabolites with potent agonist activity.
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  • Brevard Community College
    Adjunct Professor
    Brevard Community College Apr 2011 - Jul 2011
    New York, Us
    Teaching Organic Chemistry Class and LabsManage online course material and grading system (ANGEL)
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  • Newton Engg. And Chemicals Ltd
    Plant Manager
    Newton Engg. And Chemicals Ltd Nov 1999 - Aug 2003

Pranav Patel Skills

Chemistry Medicinal Chemistry Biochemistry Science Validation Gmp Hplc Chromatography Drug Development Uv/vis Nmr Analytical Chemistry Pharmaceutical Industry Laboratory Sop Life Sciences R&d Pharmacology Research And Development Lifesciences Process Optimization Purification Standard Operating Procedure Uv/vis Spectroscopy High Performance Liquid Chromatography Cgmp Practices Generic Drugs Nanoformulations Formulation Organic Chemistry New Drug Development

Pranav Patel Education Details

  • Florida Institute Of Technology
    Florida Institute Of Technology
    Medicinal And Pharmaceutical Chemistry
  • The Maharaja Sayajirao University Of Baroda
    The Maharaja Sayajirao University Of Baroda
    Applied Chemistry
  • Sardar Patel University, Vallabh Vidyanagar
    Sardar Patel University, Vallabh Vidyanagar
    Chemistry

Frequently Asked Questions about Pranav Patel

What company does Pranav Patel work for?

Pranav Patel works for University Of South Florida

What is Pranav Patel's role at the current company?

Pranav Patel's current role is Collaborative Professor.

What is Pranav Patel's email address?

Pranav Patel's email address is pr****@****sgn.bio

What schools did Pranav Patel attend?

Pranav Patel attended Florida Institute Of Technology, The Maharaja Sayajirao University Of Baroda, Sardar Patel University, Vallabh Vidyanagar.

What skills is Pranav Patel known for?

Pranav Patel has skills like Chemistry, Medicinal Chemistry, Biochemistry, Science, Validation, Gmp, Hplc, Chromatography, Drug Development, Uv/vis, Nmr, Analytical Chemistry.

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