Prashi Jain Email and Phone Number
Prashi Jain work email
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I am a collaborative scientist with >12 years of experience in drug discovery, medicinal chemistry and immuno-oncology. My work involved various hit-to-lead identification and development projects as anti-bacterial, anti-HCV, dopamine antagonists and anti-Alzheimer agents. My research is currently focused on immuno-oncology where I identified a specific role of Tregs in cancer biology. I'm also developing cell-based therapies to mitigate tumor growth.I thrive on novelty in research and have always exploited technological advances to accelerate drug discovery in my projects. I complement research with entrepreneurship and am very interested in startup culture. As a core member of our team at the 'Freedom from Cancer startup Challenge' in partnership with The Center for Advancing Innovation (CAI) and MedImmune , I was involved in the due diligence with IP and de-risking of technology/method as prerequisite elements of forming a startup. I am also a part of Fannin Innovation studio as a Therapeutic Intern where I am working with a multidisciplinary team to identify potential leads, identify synthetic challenges and perform market analysis to find a niche for translational applications.My goal is to contribute toward translational research where I can combine my scientific expertise with interpersonal skills and an entrepreneurial spirit to make a direct impact in patients' lives.Core competencies: Adaptability, team building, collaborative work, logical and strategic management, creative thinking, project design, resourcefulness, planning and execution, market analysisTechnical expertise: - Medicinal chemistry: hit to lead identification, SAR, synthesis, process chemistry, fragment based drug discovery, DNA-encoded library technology, parallel synthesis, flow chemistry.- Chemical Biology: Cell based invitro models, Nano-Bret assay, T cell isolation, flow cytometry, RNA seq, qPCR, Western blot, cell culture, ELISA, cytokine assayAreas of expertise: Drug discovery, Medicinal chemistry, Immuno-Oncology
Iterion Therapeutics
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Director, Drug DiscoveryIterion Therapeutics Aug 2022 - PresentHouston, Texas, Us -
Adjunct ProfessorBaylor College Of Medicine Jan 2022 - PresentHouston, Texas, Us -
InstructorBaylor College Of Medicine Oct 2018 - Jan 2022Houston, Texas, UsOur work is focused on identifying the role of SRC-3, previously identified as oncogene, in Treg biology and the effect of SRC-3 modulation on cancer progression.- Identified the critical role of SRC-3 in regulatory T cells (Tregs), published in 2021.- Working with a cross-functional team to drive a cell based therapy forward against cancer.- Managed the preclinical projects and collaborated with startups to move SRC-3 inhibitor to clinic.- Expanded my skills to perform cell based in-vitro assays to find the binding site of small molecule inhibitors of SRC-3 and to understand related protein-protein interactions. -
Postdoctoral Fellow/ Drug Discovery LeadBaylor College Of Medicine Jun 2015 - Sep 2018Houston, Texas, Us- Developed new methodologies for sp3 enriched disubstituted piperazine scaffolds for Fragment Based Drug Discovery (FBDD). - Led the design, development and synthesis of first-in-class 3D enriched chemical fragments.- Performed market analysis, budgeted and successfully negotiated with multiple vendors for purchasing >2500 fragments saving >$200,000 in raw material costs.- Identified needs, performed extensive market analysis and use-testing of software solutions for electronic data capture, storage, and visualization of research data in e-notebooks.- Mentored three post baccalaureate students for a year. -
Scientist IiPonce Therapeutics, Inc. Jan 2022 - Aug 2022Miami , Florida , Us -
Therapeutics InternFannin Innovation Studio Sep 2021 - Dec 2021Houston, Texas, Us- Due diligence in lead identification of >1000 compounds after in-silico screening for IP consideration- Identifying strategies to accelerate the therapeutic aspect of the project to reach to the pre-clinical stage. -
Postdoctoral Researcher/ Cross- Functional Team LeadThe University Of Kansas Dec 2011 - May 2015Lawrence, Ks, Us- Optimized multiple hits to leads for new biological targets like HCV, Bacterial AraC and dopamine receptors while working with collaborators from KU, NCATS, NIDDK, NIH.- Active time management with literature search, project ideation and publication of >9 projects within 3 years of time frame resulting in 1 patent and 7 publications.- Prepared the scientific presentation slide decks and presented research findings in national and international meetings- Actively mastered the new technologies to accelerate the compound synthesis such as parallel synthesis, flow chemistry, automated chemspeed -
Project Initiator And LeadDuquesne University Jul 2009 - Nov 2011Pittsburgh, Pa, Us- Conceptulized and led multiple projects to design selective inhibitors of CDK5 as anti-Alzheimer agents to completion resulting in 7 pulications, presentations, awards and a travel grant. - Conducted risk assesment, risk minimization and prioritization of analogs by molecular modelling resulting in a 5-fold selective inhibitor for Alzheimers Disease.- Collaborated internationally and nationally to facilitate project progress and meet deadlines. - Translated knowledge from previous projects to find selective inhibitors of MEK5, a downstream pathway for breast cancer. -
Graduate Teaching AssistantDuquesne University Aug 2005 - Jun 2008Pittsburgh, Pa, UsI have helped my colleagues teaching assistants in conducting biochemistry laboratory sessions for Pharm. D. students. Also assisted my PhD advisor in literature and patent surveys for grant applications and mentored three graduate students and two undergraduate students in the laboratory. -
LecturerDepartment Of Pharmacy Sgsits Indore Jan 2005 - Jul 2005Taught undergraduate Pharmacy (2nd year) students two full courses on Pharmacognosy and Pathophysiology .
Prashi Jain Skills
Prashi Jain Education Details
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Duquesne UniversityMedicinal Chemistry -
Shri G S Institute Of Technology & ScienceMedicinal Chemistry -
Shri G S Institute Of Technology & SciencePharmacy
Frequently Asked Questions about Prashi Jain
What company does Prashi Jain work for?
Prashi Jain works for Iterion Therapeutics
What is Prashi Jain's role at the current company?
Prashi Jain's current role is Collaborative Scientist - Medicinal Chemist - Drug Discovery Scientist - I can make things happen.
What is Prashi Jain's email address?
Prashi Jain's email address is ra****@****ail.com
What schools did Prashi Jain attend?
Prashi Jain attended Duquesne University, Shri G S Institute Of Technology & Science, Shri G S Institute Of Technology & Science.
What skills is Prashi Jain known for?
Prashi Jain has skills like Team Management, Business Analysis, Crm, Management, Agile Methodologies, Requirements Analysis, Microsoft Excel, Business Development, Business Strategy, Employee Engagement, Team Building, Data Analysis.
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