Prof. Dr. Patrick Most Email and Phone Number
Research into the molecular causes and mechanisms of disease has a high potential for innovation and value creation. We are breaking new ground in order to make the findings of basic medical research and clinical care available for the recovery of our patients and the benefit of our society. This allows us to develop therapeutic and diagnostic concepts with high efficiency and quality to the biotechnological prototype stage, which marks the professional interface at the transition from academic to post-academic space. Our inaugural success in establishing and exiting a biotech start-up, InoCard GmbH, in 2014 and 2017, respectively, exemplifies this commitment. The expertise garnered through these endeavors serves as a solid foundation for future professionally designed ventures, such as AaviGen GmbH (https://aavigen.com), which consistently advances the therapeutic and diagnostic concepts of InoCard. Our mission is to provide personalized precision medicine for cardiovascular and cardiopulmonary diseases. We achieve this by combining the strengths of the academic and bioindustrial (post-academic) sectors and challenging traditional thought patterns. A current focus is on the use of nucleic acid- and peptide-based therapeutics, which can be targeted to the heart muscle by organ-specific adeno-associated viruses (AAV), among other things.Drawing from our experience as founders of InoCard and AaviGen in an academic environment, the development and management of uniQure Germany in Heidelberg as a model project, and as uniQure leadership team member in an international environment, we bring a unique blend of medical and scientific expertise, coupled with the economic acumen and experience of the biotech industry.With the previous financing rounds for AaviGen (https://aavigen.com), the strategic partnerships and our SAB, we have laid a solid foundation for the clinical transition of the next generation of precision gene therapies for genetic and acquired forms of heart failure. If you are interested, please visit our AaviGen linkedin account to find out about the latest developments as our start-up enters the next stage of growth.
University Of Heidelberg
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Professor AbteilungsleiterUniversity Of HeidelbergHeidelberg, Bw, De -
Professor AbteilungsleiterUniversity Of Heidelberg Jun 2010 - PresentHeidelberg Und Umgebung, Deutschland- Chair, Molecular and Translational Cardiology Division, Heidelberg University Hospital, University of Heidelberg (June 2010)- Translational academic research facility/ pipeline for molecular therapy and theranostic development; USP: biotechnological/-pharmaceutical compatability- Inventor of the S100A1 technology for cardiac, vascular and pulmonary diseases- Co-founder of InoCard GmbH (aquired by uniQure NV; licensed to Bristol-Myers Squibb)- Co-founder of AaviGen GmbH -… Show more - Chair, Molecular and Translational Cardiology Division, Heidelberg University Hospital, University of Heidelberg (June 2010)- Translational academic research facility/ pipeline for molecular therapy and theranostic development; USP: biotechnological/-pharmaceutical compatability- Inventor of the S100A1 technology for cardiac, vascular and pulmonary diseases- Co-founder of InoCard GmbH (aquired by uniQure NV; licensed to Bristol-Myers Squibb)- Co-founder of AaviGen GmbH - Personalized, Precise, Simple, Safe Show less -
Gründer Und Ceo Biomedizinisches Start-Up Aavigen GmbhAavigen Gmbh - Personalized, Precise, Simple, Safe Apr 2019 - PresentHeidelberg Und Umgebung, DeutschlandGründer der AaviGen GmbH. Die AaviGen (https://aavigen.com) setzt auf dem Erfolg der InoCard GmbH auf und verfolgt das Ziel der Entwicklung und Kommerzialisierung personalisierter rAAV-basierter Gentherapien kardiovaskulärer und kardiopulmonaler Erkrankungen mit der ersten Leitindikation Herzmuskelschwäche.
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Managing Director Uniqure Germany GmbhUniqure Aug 2014 - Sep 2017Heidelberg Und Umgebung, Deutschland- Founder of InoCard GmbH (Dec. 2013); aquired by uniQure NV (July 2014), licensed to Bristol-Myers Squibb (April 2015)- Inventor of patented S100A1 technologies (Nucleic acid and peptides) against cardiac diseases- Managing Director of uniQure GmbH Germany (Cardiac/heart failure gene therapy program) with the purpose to lead pre-clinical and clinical AAV-S100A1 heart failure therapy development -
Gründer Und Ceo Biomedizinisches Start-Up Inocard GmbhInocard Gmbh Dec 2013 - Jul 2014Heidelberg Und Umgebung, DeutschlandGründer und CEO der InoCard GmbH mit erfolgreichem Exit 2014/2017. Die InoCard GmbH verfolgte das Ziel der Entwicklung einer rAAV9-basierten S100A1 Gentherapie der chronischen Herzmuskelschwäche. Das InoCard S100A1 Gentherapieprogramm wurde unmittelbar nach ihrer Gründung durch die niederländische Gentherapiefirma uniQure vollständig akquiriert und Grundlage einer umfassenden und andauernden Entwicklungspartnerschaft mit Bristol-Myers Squibb.
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Associate Professor Of MedicineThomas Jefferson University Sep 2006 - Jun 2010Großraum Philadelphia Und Umgebung- Faculty appointment in Sept. 2006 in the Division of Cardiology, Department of Medicine- PI within the Center for Translational Medicine; Laboratory for cardiac stem cell & gene therapy
Prof. Dr. Patrick Most Skills
Prof. Dr. Patrick Most Education Details
Frequently Asked Questions about Prof. Dr. Patrick Most
What company does Prof. Dr. Patrick Most work for?
Prof. Dr. Patrick Most works for University Of Heidelberg
What is Prof. Dr. Patrick Most's role at the current company?
Prof. Dr. Patrick Most's current role is Professor Abteilungsleiter.
What schools did Prof. Dr. Patrick Most attend?
Prof. Dr. Patrick Most attended Ruprecht-Karls-Universität Heidelberg, Thomas Jefferson University.
What skills is Prof. Dr. Patrick Most known for?
Prof. Dr. Patrick Most has skills like Research, Cardiology, Gentherapie, Translationale Medizin, Molecular Biology, Biowissenschaften, Molekularbiologie, Medizin, Start Ups, Unternehmertum, Life Sciences, Biotechnology.
Who are Prof. Dr. Patrick Most's colleagues?
Prof. Dr. Patrick Most's colleagues are Anke Braun, Michael Wormit, Monica Juneja, Negar Abdali, Gorenflo Matthias, Liane Wendt, Kristian Ivanov Mletiev.
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