I am a practicing Orthopedic and Neuro Surgeon with over 40 years of Clinical experience.As a surgeon practicing orthopedics for thirty five years, I have used fluorine in treating osteoporosis patients still the Indian government banned its availability. Also I am witnessing the sufferings of chronic fluorosis patients with cervical compressive myelopathy, who come to me for laminoplasty surgery. This extreme of utility and hazard have kindled my interest in taking up this work of optimizing fluorine concentration in phosphate based bio-glass so that its bone anabolic property can be utilised to create an ideal bone graft substitute. It is my life long dream and passion to identify “better synthetic bone substitutes”.