1. Oversaw antibody discovery campaign process2. Led a cross-function team for antibody discovery automation3. Represented department on project teams to achieve project milestones. Trained junior scientists for the role of antibody discovery lead member of project team 4. Established Beacon single cell screening platform that increased the antibody hit number to thousands per target5. Directed animal immunization and screening activities6. Managed external CROs for animal immunization and therapeutic antibody discovery

1. Supervised high throughput antibody transient transfection and FACS screening activities 2. Led animal immunization and antigen-specific B cell sorting for antibody discovery3. Strategized a novel antibody discovery approach for isolation of antibodies against highly difficulty targets (multiple alleles and isoforms or high homology)4. Developed a single B cell culture method that resulted in a patent for one antibody in phase I clinical trial5. Participated project teams to drive projects to achieve milestones6. Supervise Master's Co-op students and junior scientist

1. Established multiple assays such as FRET, antibody internalization, and functional assays to screen antibody candidates2. Designed and executed animal immunizations for therapeutic antibody generation3. Developed a rat antigen-specific sorting strategy and successfully applied to isolate antibodies against 24 immunology and immuno-oncology targets4. Executed high throughput PCR to amplify antibody variable sequences and cloned into expression vectors 5. Supervised Master's Co-op students and associates

1. Identified a new mechanism for infection-triggered autoimmune diseases and the results were published in Nature Immunology2. Generated an antibody against peptide/MHC for identification of cells activating CD8 T cells and published the data on Nature Immunology3. Investigated the tolerance of T cells that recently mature from thymus and the results were published in JEM

Isolated and characterized a TCR against tumor antigen for transgenic mouse generationStained Gr-1+ myeloid suppressor cells in tumor-bearing mice