Rakesh Datta Email and Phone Number
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Ph.D. with 30 years of experience in Research and Development - 12 yrs in academic settings, including 9 yrs as a faculty member at the Harvard Medical School - 14 years in the pharmaceutical industry as a group leader for drug discovery and development - 4 years as a consultant specializing in Drug Discovery & DevelopmentExpertise and extensive experience in Molecular Biology, Cellular Biology, Pharmacology, and Project ManagementExtensive knowledge and experience with drug development processesDeveloped and managed state-of-the-art in vitro drug discovery pharmacology lab Managed a group of up to 10 scientists/associate directors. Experience in recruiting talent and fostering a culture of innovation, teamwork and high performance.Successfully lead several international project teams with multi-site representation of various functions. Extensive experience in selection and management of CROs, and academic/pharma collaborationsTrack record of successfully lead developing drug candidates from early discovery to clinical development Experience with drug development strategies in the fields of Endocrinology, Oncology and GI disordersExperience in leading and taking part in due-diligence assessment of exceptional technologies and drug candidates. Played key role in the successful out licensing several drug productsOrganized/Chaired advisory panel meetings with opinion leaders in targeted disease areasInvited speaker at international congressesAuthored more than 80 publications in high impact journals
Alexion Pharmaceuticals, Inc.
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- alexion.com
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- 5060
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Pharmacology ConsultantAlexion Pharmaceuticals, Inc.Brookline, Ma, Us
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ConsultantAmolyt Pharma Sep 2021 - PresentEcully, FrAmolyt Pharma, a clinical stage biotechnology company, is building on team's established expertise in therapeutic peptides to deliver life-changing treatments to patients suffering from rare endocrine and related diseases. -
PrincipalInno-Cure Consultants Nov 2014 - PresentAn innovative consultancy specializing in Drug Discovery & Development Provide strategic consulting services to life sciences based ventures. Specialize in Due Diligence, Assessment of druggable assets, Drug Discovery, Target & Lead Identification, Mechanism of Action, Pre-clinical proof-of-concept, Early Clinical Development, Alliance Development and Management with opinion leaders.
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Director, Molecular & Cellular Biology / In Vitro PharmacologyIpsen Pharma Aug 2010 - Oct 2014Boulogne Billancourt, FrProvided leadership and direction across multiple work-streams, advancing the company’s strategic direction and supporting portfolio management goals. Managed in vitro drug discovery and pharmacology group of up to 10 scientists. Coordinated and oversaw lab functions, including targeted/whole genome expression analysis, gene knock down and cloning, generation of recombinant cell lines, development and validation of assays, screening of libraries of compounds with assays / tools, subcellular localization, high content imaging, cell growth, and cell signaling. Instrumental in implementing automation and high throughput capabilities. Strategize, plan, and execute exploratory research focused on the discovery and validation of new drug targets or discovery of novel clinical utility. Managed and participate in due diligence efforts for in and out-licensing opportunities. Partnered with functional leaders to establish and track budget. Trained and mentored project leaders and team members. Key Achievements: Led and participated in several cross-functional project teams involved in scientific evaluation/due-diligence of novel concepts/technologies and drug candidates to fulfill Ipsen’s strategic needs.Led project from lead identification to candidate validation aimed at treating hyper-secretion of growth hormone by pituitary adenoma. Established and managed alliances with academic investigators to undertake highly specialized pharmacological studies. Program is currently in Clinical development.Led due-diligence of a technology platform of a biotech company developing novel protein-based targeted secretion inhibitors to treat endocrine tumors. Contributions led to the acquisition of Biotech Company by Ipsen. -
Global Project LeaderIpsen Pharma 2009 - 2010Boulogne Billancourt, FrDirected a team of project leaders performing drug discovery projects across three global locations. Contributed to the development of a project management framework, establishing standardized guidelines for drug discovery projects, including concept assessment, lead identification, lead optimization, and candidate validation.
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Project Leader / Head Of Molecular & Cellular BiologyIpsen Pharma 2000 - 2009Boulogne Billancourt, FrSupervised Molecular & Cellular Biology group tasked with developing novel biological tools and assays to screen and test compounds used to select lead drug candidates. Served as Research Project Leader and Team Member for numerous early- and late-stage drug discovery programs; developed and managed research algorithms, risk assessments, mitigation plans, and rationale decision gates; established and tracked milestones and deliverables. Orchestrated academic and pharmaceutical collaborations; forged and maintained alliances with contract research organizations (CROs). Key Achievements: Evolved Ghrelin program from concept assessment to pre-clinical development as Project Leader; directed evaluation of drug candidates for utility in GH deficiency, cachexia associated with aging, cancer, cardiac failure, and renal failure.Discovered novel clinical utility of lead candidate in GI motility-related disorders, including post-operative lleus, diabetic gastroparesis, colitis, and chronic constipation; provided major contributions to out-licensing the program to a start-up company.Continue to serve as advisor on Ghrelin program which is in phase II clinical phase for diabetic gastroparesis, anorexia nervosa, and chronic constipation.Led collaboration with UK-based company aimed to develop long-acting biopharmaceutical products.
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Assistant Professor Of Medicine, Harvard Medical SchoolDana-Farber Cancer Institute, Harvard Medical School 1994 - 2000Boston, Ma, UsEducated medical residents, post-doctoral fellows, and scientists while supervising one PhD student. Led and contributed to numerous research projects and served on faculty committees. Conducted studies to discover the role and regulation of numerous signaling protein and transcription factors involved in cellular response to multiple anti-cancer agents.Served as Principal Investigator of a four-year NIH RO1 Grant to study “Proteolytic Activation of Protein Kinase C in Apoptosis.”Authored more than 20 publications in peer-reviewed journals. -
Instructor/Research Fellow, Harvard Medical SchoolDana-Farber Cancer Institute, Harvard Medical School 1988 - 1994Boston, Ma, UsConducted studies to discover the role and regulation of numerous signaling protein and transcription factors involved in cellular response to multiple anti-cancer agents.Discovered the first radiation-inducible DNA sequence in the promoter of EGR-1 gene; the discovery led to development of a drug candidate, TNFerade, to treat cancer. TNFerade is a replication deficient adenovector for gene therapy that used discovered radiation-inducible DNA sequence to induce the expression of TNF in cancer cells. Drug candidate reached phase III clinical trial for pancreatic cancer and phase II for esophageal cancer.Authored more than 30 publications in peer-reviewed journals.
Rakesh Datta Skills
Rakesh Datta Education Details
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All India Institute Of Medical SciencesNon-B Hepatitis Virus -
Delhi UniversityZoology/ Cell Biology
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Punjab UniversityBiological Sciences
Frequently Asked Questions about Rakesh Datta
What company does Rakesh Datta work for?
Rakesh Datta works for Alexion Pharmaceuticals, Inc.
What is Rakesh Datta's role at the current company?
Rakesh Datta's current role is Pharmacology Consultant.
What is Rakesh Datta's email address?
Rakesh Datta's email address is ra****@****sen.com
What is Rakesh Datta's direct phone number?
Rakesh Datta's direct phone number is +150847*****
What schools did Rakesh Datta attend?
Rakesh Datta attended All India Institute Of Medical Sciences, Delhi University, Punjab University.
What skills is Rakesh Datta known for?
Rakesh Datta has skills like Pharmaceutical Industry, Drug Discovery, Drug Development, Biotechnology, Molecular Biology, Life Sciences, Clinical Development, Oncology, Cell Biology, Pharmacology, Peptides, Biopharmaceuticals.
Who are Rakesh Datta's colleagues?
Rakesh Datta's colleagues are Nicholas Morse, Regina Miller, Phd, Emma Dalton, Stephen Moran, Monika Barot, Daniel Staub, Gopi V.
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