• Implemented annotation pipeline including various publically available tools and databases like annovar, SnpEff, VEP, 1000 genome, NHLBI ESP, ClinVar, HGMD, TCGA, COSMIC, CGC, SIFT, PolyPhen2 etc.• Built Pipeline for processing NextGen Sequencing Data containing publically available tools as well as small tools for data manipulation and representation.• Extensive knowledge of NIH Biowulf Cluster environment and its efficient usage.• Working on TARGET NextGen data integrated with… Show more • Implemented annotation pipeline including various publically available tools and databases like annovar, SnpEff, VEP, 1000 genome, NHLBI ESP, ClinVar, HGMD, TCGA, COSMIC, CGC, SIFT, PolyPhen2 etc.• Built Pipeline for processing NextGen Sequencing Data containing publically available tools as well as small tools for data manipulation and representation.• Extensive knowledge of NIH Biowulf Cluster environment and its efficient usage.• Working on TARGET NextGen data integrated with RNA seq data generated at NCI.• Statistical analysis of the germline, somatic, SNP arrays and RNA seq data.• Illumina SNP arrays Data analysis and interpretation.• Creating a database of annotation for whole genome and patient SNPs.• CGI Whole Genome, Illumina Transcriptome, SOLiD Transcriptome, Illumina Exome, SOLiD Exome, Illumina SNP arrays, NimbleGen CGH, NGH CGH Data processing and analysis.• Helping biologists in lab on bioinformatics tools usage, and programming needs, documentation of pipelines and tools developed. Show less

Bioinformatics Computation Methods I and II)Revamp curriculum to increase efficiency of the class (10-30 Graduate Students)Assist graduate students in Bioinformatics Computational Methods and Programming LabGrade homework, quizzes, perl programs and exams

Developed scripts in Perl for database handling, parsing, wrapping in-build tools, and analyzing outputsDesigned PCR TaqMan Primer Probe solutions Updated databases with the data fetched from NCBIDeveloped tools for data analysis, uploading and representation