Dr. Raju Tippana Email & Phone Number

Brisbane City, Queensland, Australia

I am honored to be a participant in The Bridge Program 2023. This initiative is a collaborative effort between Queensland University of Technology, MTP Connect, and a consortium comprising pharmaceutical companies, universities, and industry affiliates. Each year, the program selects 100 participants nationwide to engage in a comprehensive six-month curriculum encompassing both face-to-face and online training. The focus is on the commercialization of new medicines and biotechnology.The… Show more I am honored to be a participant in The Bridge Program 2023. This initiative is a collaborative effort between Queensland University of Technology, MTP Connect, and a consortium comprising pharmaceutical companies, universities, and industry affiliates. Each year, the program selects 100 participants nationwide to engage in a comprehensive six-month curriculum encompassing both face-to-face and online training. The focus is on the commercialization of new medicines and biotechnology.The program features renowned global experts who provide training on various aspects, including regulatory, financial, scientific, and intellectual property considerations crucial for bringing new medicines to market. What sets The Bridge Program apart is the invaluable industry expertise offered by its consortium, which seamlessly integrates into venture capital and global pharmaceutical networks. This unique feature enables the program to impart specific, detailed, and practical knowledge.Overall, The Bridge Program has provided me with a deep understanding of commercialization aspects, which are fundamental to the success of any business venture. Show less

Brisbane, Queensland, Australia

• Provided scientific and technical leadership in the cGMP Quality Control department, ensuring compliance with regulatory guidelines and industry standards.• Developed and validated analytical methods to assess the identity, purity, potency, and safety of pharmaceutical products, adhering to relevant guidelines such as GLP, GMP, and ICH.• Successfully delivered on analytical milestones for plasmid DNA, recombinant protein, and vaccine production (cGMP manufacturing) projects. This… Show more • Provided scientific and technical leadership in the cGMP Quality Control department, ensuring compliance with regulatory guidelines and industry standards.• Developed and validated analytical methods to assess the identity, purity, potency, and safety of pharmaceutical products, adhering to relevant guidelines such as GLP, GMP, and ICH.• Successfully delivered on analytical milestones for plasmid DNA, recombinant protein, and vaccine production (cGMP manufacturing) projects. This includes in-process testing and release testing of drug substances and finished products, ensuring they meet the required specifications and quality attributes.• Managed and mentored a team of scientists and analysts, providing technical guidance, training, and support to ensure high-quality work and professional development.• Maintained strong supplier relationships and supported regulatory inspections.• Established new capabilities through third party connections such as o Mass Spectrometry analyses with Australian Proteomics Analyses Facility o Improvement of Host Cell Protein analysis with Cygnus Technologieso Plasmid copy number and Host Cell DNA with Bioreliance • Designed and reviewed stability studies and analytical method qualification in accordance with ICH guidelines Q1A(R2) and ICH Q 2 (R1) respectively.• Implemented and maintained a robust documentation system, including batch records, standard operating procedures (SOPs), and testing protocols, to ensure accurate and traceable records.• Effectively managed budget planning, procurement of laboratory equipment, and acquisition of essential QC reagents for diverse projects.• Communicated effectively with internal stakeholders, clients, and regulatory authorities to provide updates on quality control activities and addressed any queries or concerns.• Developed various methods (ELISA, HCP, SDS, WB, RE analyses, BCA, et.c), method qualifications and drafted their documents for various projects/clients. Show less

Brisbane, Queensland, Australia

Brisbane, Australia

Job description: Offer scientific and technical leadership in designing and developing, biochemical, molecular and cell signaling assays to identify novel drugs from Australian native plants for treating cancer and viral diseases.• Conducted literature studies to identify potential protein/drug targets• Successfully developed chemical methods to extract bioactive molecules from Australian native plants• Mentored and trained 3 PhDs and 1 master student for bioanalytical… Show more Job description: Offer scientific and technical leadership in designing and developing, biochemical, molecular and cell signaling assays to identify novel drugs from Australian native plants for treating cancer and viral diseases.• Conducted literature studies to identify potential protein/drug targets• Successfully developed chemical methods to extract bioactive molecules from Australian native plants• Mentored and trained 3 PhDs and 1 master student for bioanalytical techniques.• Managed lab of 4 post docs and 5 PhDs and 2 masters including sourcing reagents, chemicals, equipment, health and safety• Biomolecular interactions were studied using SPR (Biacore) and ELISA technologies• Developed various bioanalytical methods to characterize the extracted bioactive molecules o HPLC method to separate various biomolecules from plan extractso Cell based (prostate, breast, triple-negative cancer and VERO cells) cytotoxic assayso xCELLigence RTCA assays to determine the cell viability, cytotoxicity, proliferation and migration activitieso SDS-PAGE and western blot for the expression of target proteinso Live cell imaging of cells to identify cellular morphological changes • Identified in vitro ADME assays (pharmacokinetics) to screen the lead bioactive molecules for in vivo studies.• Scientific data collation, report writing and presentations. Show less

Brisbane, Australia

Job description: Laboratory management and technical training to staff and students at IHBI, QUT.• Instrument training & technical support for staff and students• Laboratory inductions, management of consumables, hazardous waste & risk assessments• Liaise with internal and external stakeholders • Implementation of health and safety• Maintenance of laboratory equipment• Participate in project and team meetings

Brisbane, Australia

Job description: Mentoring, demonstrating, supervising and evaluating undergraduate students at QUT on Human Anatomy (LSB-131) and Physiology (LSB-231) practical.• One to one student training for provision of direction and instruction of anatomical structures and complex physiological processes• Leading small group discussions with students, including the demonstration of anatomical models and functions• Invigilation of weekly practical, mid-semester theory and end-of-semester… Show more Job description: Mentoring, demonstrating, supervising and evaluating undergraduate students at QUT on Human Anatomy (LSB-131) and Physiology (LSB-231) practical.• One to one student training for provision of direction and instruction of anatomical structures and complex physiological processes• Leading small group discussions with students, including the demonstration of anatomical models and functions• Invigilation of weekly practical, mid-semester theory and end-of-semester practical examinations• Assistance with the marking of practical examinations Show less

Brisbane, Australia

• Organising IHBI Inspires Postgraduates Research Student Conference o Planning and execution o Team building, meetings, and updates o Fundraising and finding sponsors to support the conference• Assisting international students o QUT policies o Research facilities and Learning resources

Pharmacy Australia Centre Of Excellence, University Of Queensland

Job description: Re-engineering of Scorpion Venom Peptides with targeted delivery approach for treating cancer patients.• Designing, planning and execution of protein separation and characterization assays• Optimisation of protein separation from scorpion venom using different purification techniques• Silver and Coomassie blue staining techniques to visualise proteins• HPLC based protein characterisation• In-gel trypsin digestion to extract peptides for mass-spec… Show more Job description: Re-engineering of Scorpion Venom Peptides with targeted delivery approach for treating cancer patients.• Designing, planning and execution of protein separation and characterization assays• Optimisation of protein separation from scorpion venom using different purification techniques• Silver and Coomassie blue staining techniques to visualise proteins• HPLC based protein characterisation• In-gel trypsin digestion to extract peptides for mass-spec analyses• Concentration and formulation of proteins by:o Nitrogen vaporization and Freeze-drying• Project and resource management• Preparation of reports and group presentations Show less

Hyderabad Area, India

Job description: Design and developing biological assays to characterize the novel and FDA approved pharmaceutical drugs to treat metabolic disorders. • Finding gene / protein targets for small molecule discovery to trear metabolic disorders• Culturing of E. coli, CHO, HepG2, HEK, THP-I, & SZ-95 cell lines• Optimizing multi-step DNA / protein isolation methodologies from animal tissues / cells / blood samples• CETP enzymatic inhibition assays to screen the active… Show more Job description: Design and developing biological assays to characterize the novel and FDA approved pharmaceutical drugs to treat metabolic disorders. • Finding gene / protein targets for small molecule discovery to trear metabolic disorders• Culturing of E. coli, CHO, HepG2, HEK, THP-I, & SZ-95 cell lines• Optimizing multi-step DNA / protein isolation methodologies from animal tissues / cells / blood samples• CETP enzymatic inhibition assays to screen the active molecules• Cloning and transfection• Protein separation and purification techniqueso Column (spin) chromatography o Antibody pull down assayso Affinity / immunoprecipitation o FPLC / AKTA lipid protein separationo ID & 2D gel electrophoresis• FDA approved drug screening using cell and biochemical approacheso Cytokine expression and quantificationo Cell-based ELISA (single & multiplex) to quantify cytokineso IC-50 determination • Separation of nuclear, cytoplasmic and total proteins• Pharmacodynamics experimental lead for clinical trials – Phase I / IIo Cardiovascular atherosclerosis (DRL-17822)o Diabetes and obesity (DRL-16536)• Measure therapeutic activity of novel drugs at molecular level RNA, DNA and Protein activity studies• RT-PCR for gene expression analyses• Preparation of documentation and standard operating procedures Show less

Hyderabad Area, India

Platform bio-assay development for novel small molecules for Diabetes and Cardiovascular research

Proprietary Products R@D, Dr Reddys Labs

Hyderabad Area, India

Hyderabad Area, India

Hyderabad, Telangana, India

Job description: As a driving force behind the establishment and growth of the micronutrient business, I focused on showcasing the integral role that micronutrients play in achieving pest-free agriculture and optimizing yields. Through effective marketing and sales strategies, I successfully promoted the adoption of micronutrients within the Indian market.Key Achievements: • Executed impactful marketing and sales strategies, propelling micronutrient recognition in Indian… Show more Job description: As a driving force behind the establishment and growth of the micronutrient business, I focused on showcasing the integral role that micronutrients play in achieving pest-free agriculture and optimizing yields. Through effective marketing and sales strategies, I successfully promoted the adoption of micronutrients within the Indian market.Key Achievements: • Executed impactful marketing and sales strategies, propelling micronutrient recognition in Indian agriculture.• Achieved remarkable sales, hitting 60-70% of year one targets and elevating to 80-85% in year two, consistently praised by customers.• Enhanced processes from customer feedback, securing an impressive 80-90% satisfaction rate, surpassing industry norms.• Managed diverse sales orders from 25+ dealerships, delivering comprehensive quarterly and annual project reports.• Pioneered innovative strategies to highlight micronutrient benefits, addressing productivity, reduced chemical usage, soil health, and budget planning.o Articulated the adverse impact of micronutrient deficiencies on overall productivity.o Championed the reduction of chemical usage through the strategic adoption of micronutrients.o Provided stakeholders tools for budget planning and profit analysis in crops enhanced with micronutrients.• Mentored 6-8 teams annually, educating on advanced farming and micronutrient utilization, enhancing agricultural practices and understanding.• Navigated micronutrient market complexities, achieving sales milestones, fostering education, and promoting innovation in agriculture. Show less

Doctor Of Philosophy (Phd), Biochemistry And Molecular Biology

Activities and Societies: • Professional Membership o ASBMB (Australian Society for Biochemistry and Molecular Biology) o Australian.

Masters Research Dissertation, Protein Biochemistry

Masters Thesis "Isolation, purification and characterization of Collagen from Rat-tail tendons" at Department of Biochemistry, National.

Masters (M.Sc) In Biotechnology, Biochemistry And Molecular Biology, First

Masters Thesis "Isolation, purification and characterization of Collagen from Rat-tail tendons" at Department of Biochemistry, National.

Bachelors (Bsc), Biotechnology, Zoology And Chemistry, First