Career Highlights:*Experienced on the process development of clinical candidate*Characterized impurities profile in development/clinical candidate and developed efficient route for their synthesis*Worked on syntheses of various receptors agonists for the diseases associated with metabolic disorders and ions imbalance*Identified RDX98940, gut-restricted TGR5 agonist, as development candidate for type 2 diabetes, short bowel syndrome and chemo-induced diarrhea*Identified RDX99848, minimally absorbed farnesoid X receptor agonist, as development candidate for treatment of liver diseases; Non-alcoholic fatty liver disease (NAFLD), Non-alcoholic steatohepatitis (NASH)*Novel drug discovery resulting in the identification of Phase I human clinical candidate in infectious disease*Experience in the synthesis of small molecules as inhibitors of metalloenzymes*Synthesized sulfated and sialylated oligosaccharides as human immunodeficiency virus (HIV) and neuraminidase inhibitors *Extensive experience in peptide, glycopeptides, peptidomimetic and oligosaccharide synthesis and their purification*Synthesis of stable redox active endogenous compounds for the treatment of viral and bacterial conjunctivitis*Extensive experiences in structure activity relationship (SAR); rational, structure-based and mechanism-based drug design and large scale-up of compounds*Medicinal chemistry: Hit to Lead, and Lead Optimization; pharmacokinetics property to improve bioavailability and reduce ADME/Tox liabilities while maintaining potency*Proven track record in delivering to aggressive project delivery targets punctually and beyond expectations of partner companies and collaborators*Extensive experience with managing Contract Research Organization (CRO) for the syntheses of key building blocks *Extensive laboratory research and analytical (HPLC, LC-MS, NMR, Flash Column Chromatography) skills