Ramesh Yella, Ph.D. ✨ Email & Phone Number

Hyderabad, Telangana, India

◾️Leading a team of 9+, including two PhDs, to ensure seamless API and Intermediates Delivery Management in the CDMO business, meeting client expectations and strategic Product Roadmap goals◾️Orchestrated Market Research initiatives and Product Strategy to optimize Product Launch processes, resulting in timely delivery and enhanced customer satisfaction in the pharmaceuticals ◾️Spearheaded Quality by Design and enforced Good Laboratory Practice (GLP) standards, ensuring excellence in R&D and Product Delivery while maintaining effective client communication◾️Managing client expectations and strategic objectives by providing timely updates, resolving challenges within 24 hours, and keeping leadership informed on Product Management initiatives◾️Optimized laboratory operations through strategic Team Management and Strategic Planning, conducting regular inventory reviews and enforcing safety protocols for lab efficiency and hygiene

United States

United States

Member of an exclusive STEM graduate platform where advanced MBA-level concepts are taught by the business professionals from top 10 MBA Schools (videos, articles and written exams). Weekly case studies and discussions conducted to increase the business acumen for life science PhD's on --Corporate strategy-Mergers & Acquisitions-Organizational Behaviour-Financial Management-Operations Management

Hyderabad, Telangana, India

◾️Led a team of 5+ members to deliver 60 kg of Lumateperone API, increasing revenue and reducing manufacturing costs by 93%, resulting in the Dr. Anji Reddy Process Excellence Award, successful Product Management through DMF filing◾️Innovated a telescopic process for Bempedoic acid with a novel salt, delivering 15 kg of API, filing a patent (Appl. No: 202141000474), and completed the DMF, showcasing leadership in Research and Development (R&D)◾️Developed Remdesivir KSM on a fast track by resolving production issues and ensuring impurity purge ability, delivering 1 ton of material to the customer, demonstrating expertise in API Delivery Management◾️Strategized process development for APIs, impurity synthesis, and plant troubleshooting, achieving cost reductions and efficient technology transfers, thus enhancing Product Delivery and Product Roadmap execution◾️Collaborated with a High-Performance Team (HPT) of R&D, analytical, and process engineers to deliver APIs rapidly, employing Quality by Design principles to drive excellence in the pharmaceuticals◾️Implemented advanced methodologies like Design of Experiments (DoE), Process Analytical Tool (PAT), and genotoxic impurities purge studies to optimize Product Strategy and ensure high-quality API development

Chengdu, Sichuan, China

◾️Directed a team of 3 in the Product Development of β-Nicotinamide Mononucleotide (β-NMN) for CDMO business, ensuring on-time delivery and effective Team Management with 3 chemists to meet tight deadlines◾️Engineered a non-infringing, cost-effective process route for β-NMN, resulting in the successful delivery of 5 kg and securing a patent (WO2021/092919A1), demonstrating expertise in Product Roadmap development◾️Optimized synthetic routes to deliver advanced intermediates/KSM for prokinetic agents and nociception/orphanin FQ receptor antagonists at a 500g scale, showcasing intermediate Delivery Management◾️Designed a novel, non-infringing process route for β-Nicotinamide Mononucleotide, a global high-value product, exemplifying strategic Market Research and Product Roadmap development◾️Troubleshot and refined processes at 0.5Kg-5Kg scales, ensuring robustness and efficiency, and demonstrating advanced Research and Development (R&D) capabilities ◾️Coordinated with team members, business development, and project management to provide solutions for ongoing programs, emphasizing strategic Product Management and Strategic Planning

Japan

◾️ Played key role for small chiral molecule to deliver up to 100g scale while effectively collaborating with the teams◾️Responsible for POC/process development for advance intermediate to the Darunavir(anti-HIV drug) with chiral catalysts for stereoselective intermolecular cross-aldol reaction and increased the ee as well as purity >99%

Ramat Gan, Israel

◾️Independently designed the route and decreased synthetic steps from 4 to 1 for pyridine analogs◾️Extensively performed reaction kinetics and mechanistic studies that increased the yield, quality and resulted in 3- publications and minimized the additional human resource

Guwahati Area, India

◾️Balanced the pressure in PhD Graduation to reduce 5 years of tenure to the 3 years under exceptional supervisor transition and accomplished 13 peer-reviewed articles on 5, 6-membered heterocycles of international repute◾️Solved the correct structure of misinterpreted pharmaceutical molecule by strategic experimentation and analytical techniques that resulted in absolutely configured product, publication and achieved best poster award in international conference

Doctor Of Philosophy (Ph.D.), Newer Strategies For The Synthesis Of Heterocycles, 8.46 C.P.I

Activities and Societies: ✦ Actively participated in the departmental activities including assisting faculties as co-invigilator.

Master'S Degree, Organic Chemistry, 67.7%

Activities and Societies: ✦ Well organized the academic events while coordinated with classmates✦ Performed excellent academic progress.

Bachelor'S Degree, Chemistry, Microbiology, Botany, 72.4%

Activities and Societies: ✦ Active cricket player in team✦ Gained knowledge in best performance and best student award in participating.