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@cbset.org
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3 phones found area 617 and 781
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Rami Tzafriri is listed as Director of Research and Innovation at CBSET at CBSET, based in Cambridge, Massachusetts, United States. AeroLeads shows a work email signal at cbset.org, phone signal with area code 617, 781, and a matched LinkedIn profile for Rami Tzafriri.
Rami Tzafriri previously worked as Director of Research and Innovation at Cbset and Principal Scientist at Cbset. Rami Tzafriri holds Phd, Computer Science from The Hebrew University Of Jerusalem.
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I am an interdisciplinary quantitative scientist, with a demonstrated history of leading regulatory science and product differentiation research in a preclinical CRO setting.Since leaving academia in 2009, I have been supporting the development, regulatory evaluation and product differentiation of complex local therapies through coupling of mechanistic computational models with quantitative experimental benchtop and in vivo models. I have used this paradigm with great effect in the fields of local endovascular drug delivery (drug eluting stents, drug coated balloons), Vessel Preparation, Renal Denervation and Thrombectomy to name a few. I leverage my training in Mathematics, Physics and Biomedical Engineering to help companies accelerate and differentiate their technologies. Starting with my graduate studies I have been fortunate to operate at the interface of academic research and commercial product development. My work deriving computational models of controlled drug delivery from biodegradable devices supported the development of devices for the treatment of gingivitis, mammary tumors, ischemic tissue, drug eluting stents and drug coated balloons. Integrative understanding is achieved through the coupling of interstitial tissue transport, cell uptake and drug pharmacology. Such integrative models are typically computationally intensive due to a dependence on a large number of parameters, some of which are difficult to measure. To overcome these challenges and facilitate experimental verification, I use model reduction techniques to directly connect to experimentally apparent dynamics.Specialties: Product differentiationQuantitative analysis of tissue microanatomy and fluorescent gradientsContinuum models of tissue level heat and drug transport (PDEs) Finite element simulations of convection-reaction-diffusion modelsCell pharmacokinetics of drugs and growth factors (ODEs)Enzyme kineticsAnalytical model reduction and parameter estimation techniquesControlled release from biodegradable matrices
Listed skills include Drug Delivery, Medical Devices, Mathematical Modeling, Cell, and 12 others.
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Lexington, Ma, Us
I liaise with KOLs and lead the development of novel quantitative methods for evaluating complex therapies and in vivo models, in support of accelerated product development and differentiation. To this end, I integrate institutional efforts and the direction of CBSET's internship and fellowship programs dedicated to training the next generation of interdisciplinary transnational researchers.
Lexington, Ma, Us
I developed computational models of drug and heat distribution in tissues in support of the development of drug eluting stents, drug coated balloons and renal denervation devices.
Cambridge, Ma, Us
As a postdoctoral Fellow in Prof. Elazer Edelman’s laboratory at MIT I examined how blood flow and receptor-ligand interactions affect drug delivery from endovascular implants and tissue distribution in arteries and the myocardium. My use of computational modeling in all these domains has been integrated within an NIH/NSF/FDA joint venture to enhance the FDA Critical Path Initiative.
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Rami Tzafriri works for CBSET.
Rami Tzafriri is listed as Director of Research and Innovation at CBSET at CBSET.
AeroLeads has found 2 work email signals at @cbset.org for Rami Tzafriri at CBSET.
AeroLeads has found 3 phone signal(s) with area code 617, 781 for Rami Tzafriri at CBSET.
Rami Tzafriri is based in Cambridge, Massachusetts, United States while working with CBSET.
Rami Tzafriri has worked for Cbset and Harvard-Mit Biomedical Engineering Center.
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Rami Tzafriri holds Phd, Computer Science from The Hebrew University Of Jerusalem.
Rami Tzafriri is listed with skills including Drug Delivery, Medical Devices, Mathematical Modeling, Cell, R&D, Pharmacology, Simulations, and Laboratory.
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