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From 1978-2000 I was a tenured faculty member at New York University in chemistry (biophysical and medicinal) neuroscience, and biological psychiatry focused in the area of GPCRs, especially CCK and dopamine, and sigma-receptors. In 2000 I left the University as I had an opportunity to co-found Achillion Pharmaceuticals, Inc. (ACHN). Since that time I have served multiple roles in startup companies in the biotechnology and biopharmaceuticals industry. Two of the companies of which I was involved with as founder (ACHN) and Marinus Pharmaceuticals, Inc. (Founder and COO) (MRNS) are now public. I also played a key role in early phase operations of other successful public companies. I am currently a founder and CSO off Epalex Pharmaceuticals, a company focused on novel treatments for neurological diseases, in particular epilepsy and migraine. My goals are to bring early to late-phase discovery compounds to development candidates which will become useful clinical agents in due course.I simultaneously serve as CSO of Metagreen, Inc., a company which is focused on the role of cannabinoids in pain and epilepsy. Metagreen is developing novel processes for cannabinoid purification under GMP which has been rate-limiting in bringing these valuable materials to market. Metagreen and Eplaex have joint preclinical research programs on the uses of cannabinoids in these and other indications.Specialties: Discovery Medicinal Chemistry, Biochemical Pharmacology, Neuropharmacology, Neurophysiology, Biophysical Chemistry (Proteins/Peptides)
Almon Therapeutics
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Cso And Chief Operating OfficerAlmon Therapeutics May 2021 - PresentAlmon Therapeutics is focused upon drug development for serious degenerative neurological and ophthalmic diseases. It's central strategy involves repurposing of an existing approved ethical pharmaceutical agent in formulation with another commonly-used agent for these conditions. This enables a relatively short and well-defined path to approval of this fixed combination, which has to date been validated in multiple preclinical model systems.
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Co-Founder And Board MemberEpalex Pharmaceuticals Jan 2019 - Present
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Founder, Ceo, CsoEpalex Pharmaceuticals Mar 2013 - May 2021Epalex is a startup pharmaceutical company focused upon novel therapeutics which address unmet medical needs in the area of serious neurological diseases, especially epilepsy and migraine. The principal agent in our pipeline is an inhaled, intrapulmonary prodrug which has confirmed activity within these therapeutic areas. This development program is funded by grants from NIH which will enable Phase I studies within the near future. Epalex is further engaged in earlier-phase preclinical programs which are aimed at the development of additional small-molecule agents within these therapeutic areas.
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Chief Scientific OfficerMetagreen, Inc. Mar 2015 - Apr 2021Metagreen is focused on novel processes for the efficient extraction of cannabinoids at GMP, including cannabadiol (CBD) and other cannabinoids which allow their economic production for approved pharmaceuticals. The Company also has research programs in basic preclinical studies of cannabinoids, especially novel naturally occurring minor cannabinoids.
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Vice President, Research And DevelopmentProgenra, Inc. Jun 2010 - Mar 2013Malvern, Pa, UsResponsible for internal research programs which are at discovery level as well as external research collaborations with academic and other research institutions. Progenra is focused on ubiquitin as a molecular target and our discovery research is centered on these ubiquitin pathways, in particular deubiquitinases and ubiqutin E3 ligases -
Vice President/CofounderCacao Biotech Inc. Jan 2009 - Feb 2012Founder of company focused on development of novel antioxidant and antiviral molecules from cacao, using advanced and transgenic methods. I continue as a key consultant at this company, especially as it relates to its operations in the Dominican Republic
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Senior Vice PresidentMedkura Inc Jan 2006 - Mar 2010Pharmaceutical research and development related to a novel propofol analogue in late phase preclinical development
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Vice President, Chief Operating OfficerMarinus Pharmaceuticals Jan 2004 - Feb 2005Founder and VP of Marinus Pharmaceuticals Inc. which was venture-capitalized to introduce new orphan drugs for epilepsy and other serious neurological and psychiatric diseases. Marinus is focused on Ganaxolone, a neurosteroid related to allopregnanolone, for these disease indications. Marinus recently became a public company (MRNS) and has Gnanxolone in late-phase clinical trials.
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Director And CofounderAchillion Pharmaceuticals Inc Jan 1999 - Aug 2003Blue Bell, Pennsylvania, Usco-Founder and Director, Achillion Pharmaceuticals Inc. (http://www.achillion.com) -
ProfessorNew York University Nov 1978 - Jan 2000New York, Ny, UsPrimary appointments in Chemistry and Neuroscience, focused on biochemical pharmacology of GPCR systems, in particular dopamine and cholecystokinin, ranging from chemical synthesis of appropriate probe molecules and pharmacophores to behavioral and physiological studies of the actions of these agents in vitro and in vivo. -
Adjunct Associate Professor Of Biochemistry In PsychiatryCornell University Jan 1985 - Jan 1997Ithaca, Ny, UsWorked in the Bourne Research Laboratory where I had a funded program in collaboration with Gerard P. Smith and James Gibbs to study neuropeptides in the gastrointestinal system. Was full time in summers and spend a full sabbatical year in residence there. Foucs on antagonists of cholecystokinin and other neuropeptides -
Research Chemist (Analytical Chemisry)National Institute Of Standards And Technology Jun 1976 - Nov 1978Gaithersburg, Md, UsWorked in ultratrace measurement of radioisotopes and stable isolopes in relation to biological and environmental problems -
Adjunct Research ChemistNational Institutes Of Health May 1975 - Nov 1978Bethesda, Md, UsWorked in the laboratory of Dr. Harry Saroff on Hemoglobins -
Adjunct Assistant ProfessorUniversity Of Maryland 1977 - 1978College Park, Md, UsWorked in the laboratory of Dr. Cyril Ponnamperuma
Randall Murphy Skills
Randall Murphy Education Details
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UclaMedicine -
UclaChemistry (Chemical Physics) -
University Of Southern CaliforniaChemistry -
Pepperdine University
Frequently Asked Questions about Randall Murphy
What company does Randall Murphy work for?
Randall Murphy works for Almon Therapeutics
What is Randall Murphy's role at the current company?
Randall Murphy's current role is CSO and Chief Operating Officer at Almon Therapeutics.
What is Randall Murphy's email address?
Randall Murphy's email address is ra****@****net.com
What is Randall Murphy's direct phone number?
Randall Murphy's direct phone number is +121588*****
What schools did Randall Murphy attend?
Randall Murphy attended Ucla, Ucla, University Of Southern California, Pepperdine University.
What are some of Randall Murphy's interests?
Randall Murphy has interest in Photograph, Cooking, Exercise, My Interests Have Been In Neuroscience, Electronics, Medicine, Investing, Home Improvement, Psychopharmacology, Reading.
What skills is Randall Murphy known for?
Randall Murphy has skills like Biotechnology, Clinical Development, Pharmaceutical Industry, Drug Discovery, Pharmacology, Medicinal Chemistry, R&d, Lifesciences, Clinical Trials, Technology Transfer, Organic Chemistry, Biochemistry.
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