Rathi Saravanan Email & Phone Number

Scientist cum Health Professions Educator with strong academic research background in structure-based drug design, discovery, preclinical development and delivery of biopharmaceuticals for global public health threats: antibiotic resistance, infection, inflammation (Sepsis) and chronic wounds. My research focused on developing peptide antimicrobials, anti-inflammatory therapeutics and diagnostic tools for control and treatment of infectious diseases. Over the years, I have identified three dimensional structures, investigated molecular mechanism of drug action and validated therapeutic efficacy/toxicity of several naturally occurring bioactive peptides and engineered peptidomimetics. Competencies: Analytical Biochemistry, Biophysics, Structure based drug design, De novo design, Quantitative structure-activity relationships (QSAR), NMR structure determination, biomolecular interactions, chromatography - affinity, Ion exchange (IEX), Reverse phase (RPC) (HPLC/FPLC) circular dichroism (CD) spectroscopy, fluorescence spectroscopy, isothermal titration calorimetry (ITC), dynamic light scattering (DLS), bioassays (e.g. antimicrobial, cytotoxicity, serum stability assays), cell culture, molecular cloning, protein expression (E. coli, yeast), large-scale protein purification and molecular biology methods Grant/Proposal writing, Business plan writing, Project development and budget management, Resource management; Fund disbursement

Listed skills include Spectroscopy, Cell Biology, Elisa, Western Blotting, and 19 others.