Raul Bortolin, Phd Email and Phone Number
Raul Bortolin, Phd work email
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Raul Bortolin, Phd personal email
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I am an experienced pharmaceutical researcher with a deep commitment to advancing the field of pharmacology, toxicology, and biomarker discovery. Over the past 9 years, I have been particularly focused on cardiometabolic diseases, exploring gene therapies for cardiac conditions, evaluating drug-induced toxicity, and searching for novel therapeutic and early diagnostic targets, contributing to over 50 peer-reviewed publications and securing a patent in the process.My core expertise lies in the design and implementation of clinical, in vitro, and in vivo studies, all essential for advancing translational medicine and personalized healthcare solutions. I have led multiple projects, effectively translating complex research into viable drug candidates ready for clinical trials, thus accelerating their path to real-world applicationI specialize in iPSC technology, mastering the use of cardiomyocytes, hepatocytes, and skeletal muscle cells across both traditional and advanced 3D cultures. My work in optimizing the process of establishing master cell banks has significantly streamlined the phases of drug development, ensuring efficiency and effectiveness.Throughout my career, I have also focused on mentoring a dynamic team of researchers, fostering their growth, and overseeing the successful completion of numerous projects. My ability to collaborate effectively has allowed me to build and nurture valuable partnerships that enhance our collective research impact, directly benefiting patient care.I am passionate about contributing to an environment that values meticulous research, collaborative spirit, and innovative breakthroughs. I thrive in settings that appreciate proactive leadership and flexibility, and I am dedicated to making meaningful contributions that enhance both scientific understanding and patient outcomes.I am excited about the opportunity to join a team that is equally committed to making significant advances in healthcare. Please feel free to connect with me at rhbortolin@gmail.com to discuss how we can collaborate or how my expertise might align with the strategic goals of your organization.
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ScientistYoh, A Day & Zimmermann Company Aug 2024 - PresentAssigned to Sanofi in Waltham, MA -
InstructorHarvard Medical School May 2023 - Aug 2024Boston, Massachusetts, United States■ Developed novel translational RNA-based gene therapies for genetic cardiac diseases.■ Conducted pharmacodynamics and toxicology assessments in iPSC-derived cardiomyocytes and genome-edited cell lines.■ Led preclinical in vivo characterization in transgenic animal models. -
Research FellowHarvard Medical School Jan 2022 - May 2023Boston, Massachusetts, United States■ Designed and implemented large-scale SOPs to create iPSC-derived cardiomyocytes 3D/organoids in bioreactors for preclinical studies.■ Established an iPSC master cell bank reprogrammed from 25 patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) for precision medicine studies.■ Mentored 2 research assistants and 2 undergraduate students in stem cell biology -
Senior ScientistBoston Children'S Hospital May 2023 - Aug 2024Boston, Massachusetts, United StatesBoston Children's Hospital is a teaching hospital affiliated with Harvard Medical School where my postdoctoral research is being developed (BCH/HMS double affiliation). -
Research FellowBoston Children'S Hospital Jan 2022 - May 2023Boston, Massachusetts, United StatesBoston Children's Hospital is a teaching hospital affiliated with Harvard Medical School where my postdoctoral research is being developed (BCH/HMS double affiliation). -
Postdoctoral Research FellowUniversidade De São Paulo Jun 2018 - Jan 2022■ Developed a metabolic modeling platform for in vitro study, drug screening, and biomarker discovery using iPSC-derived hepatocytes and gene-edited HepG2 cell lines. ■ Expert in developing iPSC-derived skeletal muscle platforms to evaluate lipid-lowering-induced myotoxicity.■ Established an iPSC master cell bank reprogrammed from 6 familial hypercholesterolemic patients.■ Analyzed lipidomic, genomics, epigenomics, and pharmacogenomics data for precision medicine.■ Conducted comprehensive dataset analysis to identify, characterize, and validate genomic, biochemical, and pharmacogenomic targets, supporting early diagnosis, drug efficacy evaluation, toxicity assessment, and advancements in precision medicine.■ Mentored 1 undergraduate student in biomarker discovery. -
Postdoctoral Research FellowUniversidade Federal Do Rio Grande Do Norte Jan 2015 - Jun 2018■ Performed clinical data analysis for diagnostics and precision medicine in cardiovascular disease and diabetes. ■ Developed in silico and in vitro assays for drug-induced liver toxicity using exosome-derived miRNAs. ■ Developed and patented a herbal-based medicine for type 1 diabetes, demonstrating significant efficacy in animal models. (patent No: BR1020190185104).■ Evaluated herbal compounds with satiogenic properties using a food-induced obesity model in rats, assessing potential treatments for obesity.■ Mentored 2 undergraduate students, 4 professionals, 3 Master and 2 Ph.D. students in molecular biology. -
Adjunct ProfessorUniversidade Federal Do Rio Grande Do Norte Jul 2011 - Jul 2013Brazil* Taught Pharmacology for 2 years to ~ 1000 life science undergraduate students.
Raul Bortolin, Phd Education Details
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Pharmacology -
Pharmaceutical Sciences -
Pharmacology
Frequently Asked Questions about Raul Bortolin, Phd
What company does Raul Bortolin, Phd work for?
Raul Bortolin, Phd works for Yoh, A Day & Zimmermann Company
What is Raul Bortolin, Phd's role at the current company?
Raul Bortolin, Phd's current role is Scientist | Expert in Stem Cell & Gene Therapy, Pharmacology & Toxicology | Novel Target Discovery Specialist | Strategic & Creative Problem Solver | Cooking Enthusiast.
What is Raul Bortolin, Phd's email address?
Raul Bortolin, Phd's email address is ra****@****.com.br
What schools did Raul Bortolin, Phd attend?
Raul Bortolin, Phd attended Universidade Federal Do Rio Grande Do Norte, Universidade Federal Do Rio Grande Do Norte, Universidade De Ribeirão Preto.
Who are Raul Bortolin, Phd's colleagues?
Raul Bortolin, Phd's colleagues are Claire Schweppe, Leo Navarro, Ronald Lee, Michael Mcconaughey, Stephanie Williams, Jason Green, Ayuk John Ebot Ebot.
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