Extensive experience in chemical development with expertise in working from candidate selection, preclinical to late phase and to commercial launch. Lead projects to ensure timely delivery of objectives, including: drug substance, new synthetic routes, robust manufacturing processes, outsourcing activities with CROs & CMOs, impurities, analytical methods and specifications, technology transfer to production sites, regulatory dossiers and other documentation to support the projects. Originate ideas, lead and supervise efforts for the solution of project related problems, including the conception and realization of viable new synthetic routes and the solution of specific process development problems. Focused on interacting with wide range of different functions (preclinical & clinical, EQA, QA, regulatory) to achieve drug substance objectives. Key competencies:• Project leadership • Route development/improvement• Experience with CROs/CMOs• Analytical methods & specifications• Regulatory & quality compliance • Risk assesment• Quality by design• Technology transfer• Validation• Regulatory submissions My accomplishments include:• Received number of impact awards (27) including GSK’s two Exceptional Science Awards.• Invented commercial manufacturing process to Tapinarof API synthesis (approximately 90% cost reduction vs initial route A).• Led and executed conditions which resulted in 90% cost reduction to final commercial manufacturing pazopanib hydrochloride (Votrient) synthesis.• Proposed and executed Quality by Design (QbD) principles to Votrient & Tapinarof synthesis.• Supervised >200+ pilot plant runs at CROs/CMOs, GSK’s R&D and commercial sites for the API deliveries.• Developed Manufacturing and Supply sourcing strategies, and contract manufacturing partner selection for raw materials, impurities, starting materials, advanced intermediates, and APIs.• Experienced at managing the internal and external projects (CROs/CMOs) and leading multidisciplinary teams.