Raymond S. Oh, Phd Email & Phone Number

Bedford, Ma, Usa

United States

Bedford, Ma

Antisense drug discovery

Framingham, Ma

Lung fibrosis drug discovery

Harvard School Of Public Health

Department of Environmental HealthSupervisor: Dr. Daniel Tschumperlin• Sponsored by Boehringer-Ingelheim, developed a novel, robust, and quantitative cell phenotypic assay for large-scale RNAi screening for lung fibrosis genes; optimized this high-content imaging approach to 2D hydrogel culture conditions• Executed a large-scale siRNA screen, including all data management and statistical analysis; generated a panel of 30 highly validated hit genes (tested in patient primary cells and in hydrogel conditions) • Delivered regular oral and written progress reports to industry partner and proposed future studies• Screen results supported a successful NIH-R01 grant application; abstract accepted for presentation at 19th International Colloquium on Lung and Airway Fibrosis 2016; publication in preparationDepartment of Genetics and Complex DiseasesPostdoctoral fellow, supervisors: Drs. Quan Lu, Gokhan Hotamisligil• Identified through genome-wide RNAi screening genes that modulate arsenic toxicity resulting in first author JBC publication; elucidated a metabolic signaling pathway linking amino acid uptake (SNAT2) and endoplasmic reticulum stress; this work supported a successful NIH-R01 grant application• Elucidated a novel role for arrestin domain-containing protein 1 in vesicle budding, resulting in contributing author PNAS publication

Toronto, On, Canada

Program in Genetics and Genome Biology; Department of Molecular Genetics, University of TorontoSupervisor: Dr. Johanna Rommens• Cloned and characterized human ubiquitin-conjugating enzyme genes (UBC6 family) resulting in first author JBC publication; elucidated their role in CFTR degradation with enzymatic assays and cell culture models of cell stress and proteostasis

Doctor Of Philosophy (Phd), Molecular Genetics

Bachelor Of Science (Bsc), Biochemistry