Ryan Caldwell, Phd Email & Phone Number

Alpharetta, Ga, Us

Alpharetta, Georgia, United States

Steering the technical design and testing of an exciting neuromodulation needle electrode device that will deliver days-to-weeks of drug-free post-surgical pain relief. Coordinating across an exceptional cross-collaborative team to stay ahead of key risks to product verification, clinical testing, and production transfer, and reduce critical path to commercialization.• Designed electrode embodiment based on DFM principles, vetted with customers through human factors studies• Strategized… Show more Steering the technical design and testing of an exciting neuromodulation needle electrode device that will deliver days-to-weeks of drug-free post-surgical pain relief. Coordinating across an exceptional cross-collaborative team to stay ahead of key risks to product verification, clinical testing, and production transfer, and reduce critical path to commercialization.• Designed electrode embodiment based on DFM principles, vetted with customers through human factors studies• Strategized benchtop and preclinical studies to answer key questions and drive product requirements • Coordinated project schedule and cadence meetings to meet milestone deliverables • Communicated candidly and listened actively to be appraised of technical and individual/team issues, intervened as needed to balance resourcing, advocate solutions, and mentor junior team members through challenges • Reviewed IP and identified FTO opportunity, authored multiple patents and disclosures• Developed test methods pertinent to ISO and IEC standards, coordinated validations/MSA• Worked with vendors/suppliers to iteratively develop and align on component specifications and inspection criteria, Show less

Alpharetta, Ga

• Executed and reported pre-clinical studies and computer simulations to elucidate relationships between electrode architecture and electrical/thermal fields that drive selective neural treatments.• Worked in collaboration with an external partner to develop an ultrasound-visible percutaneous bipolar electrode lead capable of residing migration-free for 7 days; planned and executed preclinical studies to evaluate relationships between lead design and internal migration• Collaborated to… Show more • Executed and reported pre-clinical studies and computer simulations to elucidate relationships between electrode architecture and electrical/thermal fields that drive selective neural treatments.• Worked in collaboration with an external partner to develop an ultrasound-visible percutaneous bipolar electrode lead capable of residing migration-free for 7 days; planned and executed preclinical studies to evaluate relationships between lead design and internal migration• Collaborated to secure company-first IRB approval for non-significant risk clinical study utilizing percutaneous protoypes; helped plan and execute clinical studies at multiple clinician sites• Authored disclosures and patents; advised on valuation of external technologies within expertise Show less

Salt Lake City

Conducted research and assisted fabrication of neural implants, particularly the Utah Electrode Array (see picture). Provided general support for all experiments and implant fabrication/testing, including solid design and machining, PCB layout and sourcing, photolithography mask design, systems support for data acquisition, material imaging and characterization, and technical reports/presentations.• Identified failure mechanisms and corrective process actions for metal deposition on… Show more Conducted research and assisted fabrication of neural implants, particularly the Utah Electrode Array (see picture). Provided general support for all experiments and implant fabrication/testing, including solid design and machining, PCB layout and sourcing, photolithography mask design, systems support for data acquisition, material imaging and characterization, and technical reports/presentations.• Identified failure mechanisms and corrective process actions for metal deposition on electrodes, directly helping to bring in awards of more than $910k for federal and industry research.• Proactively developed an algorithm to generate complex impedance spectra from recorded microelectrode waveforms, to monitor electrode performance. Submitted invention disclosure.• Coordinated electrode array fabrication per cGMP protocols, for external customers. Addressed unique customer needs through process innovation. Interfaced with customers to ensure metrics were met.• Designed, executed experiments and statistical analyses to evaluate implantable moisture barriers. Authored full report under review for publication. Published initial work in Transducers 2015 proceedings.• Spearheaded collaborative project with FDA to evaluate polymer tests that simulate in vivo aging. Managed test device fabrication, testing, and analysis to meet deadlines. Presented results at NANS 2017.• Created HW/SW data acquisition and processing protocols for electrode pulse testing. Trained all users.• Investigated processes and designs for flexible implantable electrodes, including fabrication with parylene C, atomic layer deposited aluminum oxide, SU-8, polycarbonate urethane, and silicone.• Developed an FEA model of failure modes for neural electrodes, to distinguish the performance of distinct electrode components and inform more robust device design. Show less

Thousand Oaks, Ca

• Utilizing SolidWorks, Autodesk Inventor, and working with senior management, co-developed an automated microplate-volume QC device. Designed and integrated a critical sealing interface, improving reliability over 50%.• Prepared and presented prototype performance results with industry partners at Lab Automation 2011, generating market interest and product demand, culminating in IP acquisition.• Conducted manufacturing-oriented solid design, manual milling, and sourced… Show more • Utilizing SolidWorks, Autodesk Inventor, and working with senior management, co-developed an automated microplate-volume QC device. Designed and integrated a critical sealing interface, improving reliability over 50%.• Prepared and presented prototype performance results with industry partners at Lab Automation 2011, generating market interest and product demand, culminating in IP acquisition.• Conducted manufacturing-oriented solid design, manual milling, and sourced components for multiple projects. Show less

Oxnard, Ca

• Aided cell counting, histology preparation, subject monitoring, general lab prep and cleanliness.

Philadelphia, Pa

• Conducted spectroscopic experiments to establish liquid-phase paint color control protocol.

Westlake Village, Ca

• Utilizing Good Documentation Practices, managed SOP archives and organized document vault.

Doctor Of Philosophy - Phd, Bioengineering, 3.94

Activities and Societies: Integrative Graduate Education and Research Traineeship (IGERT) Neural Engineering Research Group (NERG).

Bs, Bioengineering, 3.88 Gpa

Activities and Societies: Pi Kappa Alpha Bioengineering focus: Neuroengineering. Minor: Electrical Engineering. Senior design project.