Postbaccalaureate Intramural Research Award Fellow
Bethesda, Maryland, United States
I'm affiliated with three teams across the NIH. At the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), I work with Dr. Kong Chen to identify and characterize the components of energy metabolism across different clinical populations. Additionally, I am a member of the Metabolic Clinical Research Unit (MCRU) led by Dr. Chen. Here, I collaborate with a variety of teams throughout the NIH Clinical Center to provide metabolic testing for their patient populations. Testing involves using whole-room indirect calorimeter rooms or carts, and body composition assessments using DEXA and 3D Body scanners, Bioelectric Impedance Spectroscopy, and Bod Pod tests.In conjunction with the lab of Dr. Aaron Cypess, we connect aspects of energy metabolism to characterize, recruit, and activate brown adipose tissue (BAT), a thermogenic, active organ. The therapeutics we study are aimed at activating BAT will pave avenues to burn calories and improve insulin sensitive, which will ultimately combat metabolic diseases such as type II diabetes and obesity. My projects between these two labs focus on utilizing Magentic Resonance (MR)-based imaging modalities (MRI, NMR) to image BAT volume and activity, and teasing apart the thermophysiological differences, particularly BAT and muscle response to cold stress, between Black and White lean, young men.At the National Institute of Environmental Health Sciences (NIEHS), I work with Dr. Adam Schiffenbauer from the Environmental Autoimmunity Group to evaluate the utility of DEXA imaging to assess and characterize calcinosis in patients with dermatomyositits. While computed tomography (CT) is considered the gold standard for imaging the extent of calcinosis in this patient population, DEXA provides a cheaper, more accessible, and most importantly, safer modality for imaging calcinosis. My project aims to compare CT, DEXA, and physician assessments to highlight the strengths and weaknesses of using DEXA for this purpose.