Research Associate
Edmonton, Canada
-Synthesis of polymeric biomaterials, formulation of polymer-based nanoparticle for gene, siRNA delivery, evaluation of cellular uptake, Intracellular trafficking and efficiency elucidation in both in vitro and in vivo model.-High throughput siRNA library screening to identify therapeutic targets associated with cancer cell growth, survival and drug-resistant-RNAi mediated cancer gene therapy in breast cancer leukemia models-Identification siRNA targets to sensitize… Show more -Synthesis of polymeric biomaterials, formulation of polymer-based nanoparticle for gene, siRNA delivery, evaluation of cellular uptake, Intracellular trafficking and efficiency elucidation in both in vitro and in vivo model.-High throughput siRNA library screening to identify therapeutic targets associated with cancer cell growth, survival and drug-resistant-RNAi mediated cancer gene therapy in breast cancer leukemia models-Identification siRNA targets to sensitize cancer cells against drug treatment, identification of synergistic pair (siRNA/protein, siRNA/drug, siRNA/DNA) for combination therapy and study the synergistic mechanism.-Contributing to the project of scientific discipline, investigating, creating, and developing new methods and technologies, identifying patentable inventions, participating in scientific conferences and contribute to scientific journals. Show less