Rene C. Adam, Phd

Rene C. Adam, Phd Email and Phone Number

Senior Principal Scientist at Regeneron Pharmaceuticals, Inc. @ Regeneron
tarrytown, new york, united states
Rene C. Adam, Phd's Location
New York City Metropolitan Area, United States
Rene C. Adam, Phd's Contact Details

Rene C. Adam, Phd work email

Rene C. Adam, Phd personal email

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About Rene C. Adam, Phd

Innovative epithelial biologist with strong knowledge of stem cell epigenetics, tissue regeneration and lipid metabolism. Demonstrated research expertise in cellular and molecular biology of tissue wound repair vs. tumorigenesis, evidenced by strong publication record (including in Nature, Cell, Cell Stem Cell, Nature Cell Biology and PNAS). Experienced in developing and optimizing in vivo model systems to elucidate novel mechanisms in lipid metabolic pathways and their relevance to human disease.Outside the lab, I've traveled around the world and completed the NYC Marathon. I'm also great at catching typos.

Rene C. Adam, Phd's Current Company Details
Regeneron

Regeneron

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Senior Principal Scientist at Regeneron Pharmaceuticals, Inc.
tarrytown, new york, united states
Website:
regeneron.com
Employees:
9030
Rene C. Adam, Phd Work Experience Details
  • Regeneron
    Senior Principal Scientist
    Regeneron Dec 2023 - Present
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  • Regeneron
    Principal Scientist
    Regeneron Jan 2022 - Dec 2023
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  • Regeneron Pharmaceuticals, Inc.
    Scientist
    Regeneron Pharmaceuticals, Inc. Aug 2019 - Dec 2021
    • Support antibody-based therapeutics development projects in lipid disorders with in vivo and in vitro studies, resulting in FDA approval of evinacumab (Evkeeza) for Homozygous Familial Hypercholesterolemia.• Perform target discovery efforts to uncover and evaluate novel therapeutic candidates
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  • Regeneron Pharmaceuticals, Inc.
    Postdoctoral Fellow
    Regeneron Pharmaceuticals, Inc. Jul 2017 - Aug 2019
    • Independently design and perform complex in vivo studies, interpret data and present the results to collaborating scientists, project teams and senior management. Publish data in scientific journals.
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  • The Rockefeller University
    Phd Investigator In Stem Cell Biology
    The Rockefeller University Sep 2011 - Jul 2017
    Greater New York City Area
    Stem cells are versatile and fulfill different roles during development, tissue maintenance and wound repair. In the laboratory of Dr. Elaine Fuchs, I have employed ChIP-seq, RNA-seq and in vivo reporter assays to identify epigenetic mechanisms that dictate how stem cells in the skin make appropriate choices.I further discovered that SOX9 acts as pioneer master regulator whose levels define not only spatial and temporal features of lineage-status, but also stemness, plasticity in transitional states and differentiation.
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  • Prescouter, Inc.
    Team Leader/Global Scholar
    Prescouter, Inc. Oct 2015 - Dec 2016
    • Advise Fortune 500 companies to advance dermatology: create innovative new skin products and provide market feasibility reports.• Manage a team of 5 consultants to analyze emerging technologies. Provide strategic intelligence to help clients forecast the competitive landscape in their markets, resulting in a change of company strategy and focus on new product lines.• Contribute articles highlighting novel technologies to the PreScouter newsletter, reaching over 50,000 innovation leaders.
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  • The Solution Lab, Inc.
    Volunteer Analyst
    The Solution Lab, Inc. Jul 2016 - Sep 2016
    Greater New York City Area
    • Provide insights to C-suite personnel through slide decks on interdisciplinary team-based projects.• Perform interviews with key opinion leaders and secondary research to identify novel business opportunities in the undiagnosed disease space.• Analyze the competitive landscape in an emerging life sciences market to assist the client in making investment decisions.
  • University Of Graz
    Msc Candidate Investigator In Cardiac Metabolism
    University Of Graz Apr 2010 - Jun 2011
    Graz, Austria
    I could demonstrate that the hormone FGF21 is a biomarker for cardiomyopathy. Mechanistically, I found that FGF21 acts as metabolic switch in the cardiac muscle: FGF21 inhibits burning of fat but favors glucose utilization instead, thereby changing cardiac energy homeostasis.
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  • University Of Graz
    Research Assistant
    University Of Graz Jul 2008 - Mar 2010
    Graz, Austria
    Devised strategies to purify mammalian Adiponutrin (Pnpla3) protein for functional in vitro assaysDetermined sigma(32) turnover by generating GFP fusion constructs and live-imaging of E. coli
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  • University Of Cambridge
    Research Assistant
    University Of Cambridge Aug 2009 - Sep 2009
    Cambridge, United Kingdom
    Conducted a screen to investigate the effect of prostaglandins on brown adipocyte differentiationDiscovered that prostaglandin E2 inhibits brown adipocyte differentiation via the EP1R receptor
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  • Medical University Of Graz
    Research Assistant
    Medical University Of Graz Jul 2005 - Sep 2005
    Graz, Austria
    as part of the GEN-AU Summer School (GEN-AU: genome research program in Austria)Determined gene expression profiles of wildtype and FXR-deficient mice to uncover novel genes involved in cholestasis
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Rene C. Adam, Phd Skills

Molecular Biology Research Cell Biology Biochemistry Science Cell Culture Life Sciences Stem Cells Molecular Cloning Pcr Western Blotting Polymerase Chain Reaction Laboratory Fluorescence Microscopy Immunohistochemistry Protein Purification Rt Pcr Genetics Microscopy Protein Expression Biotechnology Tissue Culture Cell

Rene C. Adam, Phd Education Details

Frequently Asked Questions about Rene C. Adam, Phd

What company does Rene C. Adam, Phd work for?

Rene C. Adam, Phd works for Regeneron

What is Rene C. Adam, Phd's role at the current company?

Rene C. Adam, Phd's current role is Senior Principal Scientist at Regeneron Pharmaceuticals, Inc..

What is Rene C. Adam, Phd's email address?

Rene C. Adam, Phd's email address is ad****@****ail.com

What is Rene C. Adam, Phd's direct phone number?

Rene C. Adam, Phd's direct phone number is +184786*****

What schools did Rene C. Adam, Phd attend?

Rene C. Adam, Phd attended Rockefeller University, University Of Graz, University Of Graz.

What are some of Rene C. Adam, Phd's interests?

Rene C. Adam, Phd has interest in Writing, Stem Cell Biology, Biotechnology, Consulting, Traveling, Long Distance Running, Hiking, Science And Technology, Human Rights, Nonprofit.

What skills is Rene C. Adam, Phd known for?

Rene C. Adam, Phd has skills like Molecular Biology, Research, Cell Biology, Biochemistry, Science, Cell Culture, Life Sciences, Stem Cells, Molecular Cloning, Pcr, Western Blotting, Polymerase Chain Reaction.

Who are Rene C. Adam, Phd's colleagues?

Rene C. Adam, Phd's colleagues are Liridona Kelmendi, Ms, Tucker Olsen, Nathan Dellevigne, Jamie Akers, Mathilde Laurent, Shaunte Mcfadden, Jessica Reynoso.

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