Engaged in interdisciplinary organic chemistry projects involving peptides, carbohydrates, medicinal chemistry and complex biomolecules.Expertise in peptide synthesis (SPPS and solution); Carbohydrates; Bio-conjugations; bio-complex molecules synthesis.

Biomarkers synthesis: Carbohydrates, Peptides, conjugates, etc.Nutraceuticals

Research and Development of bacterial Polysaccharide conjugate vaccines (PCV) and other synthetic glycans.Successfully synthesized pneumococcal PCV of seven serotypes of streptococcus pneumoniae.Experience in the interdisciplinary areas of Organic Chemistry, Medicinal Chemistry, Stable isotope Chemistry and Analytical Chemistry.Successfully synthesized Glyco aminoacids, PEGlated Glycosides and Glycoconjugates, O-glucuronides, biologically relevant carbohydrates, oligosaccharides, Deuterium- labelled API’s and medicinally relevant small molecules.

• Synthesis of innate vaccines: (A liposaccharide epitope containing propriety lipids and a polypeptide sequences were synthesized and tested for its immune activity.)• Synthesis of various biological relevant molecules: viz. Antigens like STn, Tn-Ser, Tn-Threo, Pam3CSK3/4, etc., in grams scale.• Synthesis of commercial molecules: Both in gram and multi-gram scale. (Oligosaccharides, carbohydrate based molecules, peptide chains and heterocylic molecules involving multistep synthesis).• Synthesis of Sigma Aldrich catalogue molecules in gram scales: viz., Garg indolynes and pyridnes building block molecules; Baran sulfinate; Fucose derivatives; galactosylamines, etc.

Design and synthesis of Sialyltransferase Inhibitors.Methodology development of stereoselective glycosylations.Carbohydrate Chemistry

Carbohydrate Chemistry, Oligosaccharide synthesis, methodology developments, X-ray crystallography and its use in conformational studies of small molecule of biological relevance.Medicinal chemistry.