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Scientist/Team Leader with refined hands-on technical skills and supervisory experience. Expert in immunoassay development and validation. Pharmaceutical industry experience in preclinical PK/PD, development of personalized medicine applications (clinical samples, bioassay based), oral and pulmonary drug transport systems, virology, HTS, cell based assays, molecular biology, protein isolation and characterization, drug metabolism (prodrug activation), and bioanalytical analysis of protein and small molecule combination formulations. Seasoned supervisor with outstanding project management and coaching skills.
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Senior ScientistMerck Jul 2016 - PresentRahway, New Jersey, UsCell based assay development and qualification for biologics platforms including Antibody Dependent Cell mediated Cytotoxicty (ADCC), Complement Dependent Cytotoxicity (CDC), flow cytometric, and reporter gene based assays supporting CMC. -
Scientific AdministratorWeill Cornell Medicine Dec 2015 - May 2016Scientific Project Management Managed interactions between in-house Preclinical, Clinical, and GMP manufacturing operations and biotech/pharmaceutical clients, delivering regular updates on project timelines, coordinating technical meetings, and lending scientific expertise to overcome technical challenges in assay development for qPCR, anti drug antibody (ADA), and ELISA based assays.
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Bioanalytical Scientist/Development FellowBiodel Inc. Oct 2013 - Dec 2015Danbury, Ct, UsQualification and validation of immunoassays supporting preclinical analysis, in house and managed through contract research organizations (CROs)Bioanalytical and formulations development support -
Research Scientist, Molecular VirologyRoche Jul 2011 - Sep 2013Switzerland 🇨🇭 , ChQuantitative cell based analysis of the metabolism, activation, and tissue specificity of nucleoside based antiviral prodrugs targeting HCVViral bioassay development to assess the potency and cytotoxicity (EC50/CC50), of anti-HBV therapeutics selected by biochemical (IC50) screening -
Associate Director Of Cell Based Formulation ResearchMannkind Corporation Feb 2007 - Apr 2012Danbury, Ct, UsCell based drug absorption and transport mechanism research and development to elucidate the mechanism of action of delivery agents for large molecule (protein) and peptide pulmonary delivery systems associated with diabetes, osteoporosis, and weight loss.Protein and small molecule formulation stability and powder performance evalulation -
Research Scientist/Associate Director Of Cellular ScienceEmisphere Technologies May 2001 - Feb 2007UsCell based oral dug delivery research on heparin, insulin and other large (protein) and small molecule therapeuticsDirected cell based screening assays (HTS) using automated microscopy designed to identify and classify novel drug delivery agents -
Post Doctoral Research AssociateAlbert Einstein College Of Medicine Jun 2000 - May 2001Philadelphia, Pa, UsProtein Characterization: Molecular Biology/BiochemistryExtensive recombinant protein purification and analysis of dimerization domain, high affinity binding domain, and subcellular localization using site directed mutagenesisNative biochemical purification regulatory and active catalytic enzyme subunits (PKA)
Robert Angelo Skills
Robert Angelo Education Details
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Albert Einstein College Of MedicineMolecular Phamacology -
Pace UniversityBiochemistry
Frequently Asked Questions about Robert Angelo
What company does Robert Angelo work for?
Robert Angelo works for Merck
What is Robert Angelo's role at the current company?
Robert Angelo's current role is Senior Scientist at Merck.
What is Robert Angelo's email address?
Robert Angelo's email address is ra****@****orp.com
What is Robert Angelo's direct phone number?
Robert Angelo's direct phone number is +120379*****
What schools did Robert Angelo attend?
Robert Angelo attended Albert Einstein College Of Medicine, Pace University.
What skills is Robert Angelo known for?
Robert Angelo has skills like Assay Development, Protein Chemistry, Protein Purification, Cell, Elisa, Pharmaceutical Industry, Biotechnology, Hplc, Molecular Biology, Purification, Biochemistry, Cell Biology.
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