Robert Sackstein Md,Phd Email and Phone Number
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My efforts as a basic scientist and clinician are intimately intermeshed. I am a basic science immunologist/biochemist/molecular biologist with clinical expertise in internal medicine/hematology/immunology and, in particular, in hematopoietic stem cell transplantation (HSCT). Accordingly, my bench research efforts aim to elucidate biologic processes critical to improving outcomes for patients undergoing stem cell transplantation, such as: (1) hematopoiesis, and other cell and tissue regeneration from stem cell-based therapeutics; (2) tissue-specific lymphocyte migration (including the immunobiology of lymphocyte migration in host defense and in pathologic reactions such as graft-versus-host disease); and (3) pathobiology of tumor cell proliferation and tumor metastasis. The common thread for all these efforts is to manipulate the biology of cellular trafficking, as it pertains to stem cell transplantation and tissue regeneration (‘regenerative medicine’), to host defense/inflammation, and to cancer growth and metastasis.
Harvard Medical School
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Director, Program Of Excellence In Glycosciences, Harvard Medical SchoolHarvard Medical SchoolBoston, Ma, Us -
Director, Program Of Excellence In Glycosciences, Harvard Medical SchoolHarvard Medical School 2011 - PresentBoston, Ma, Us -
Physician-ScientistHarvard Medical School 1997 - PresentBoston, Ma, UsMy clinical expertise is in hematopoietic stem cell transplantation (HSCT) and throughout my career I have performed basic research with the hope of creating novel strategies to improve outcomes for my patients. My research interest is in the regulation of cellular trafficking as it relates to HSCT, with a focus on how hematopoietic stem cells traffic to marrow and how alloreactive and regulatory lymphocytes gain access to target tissues in graft-versus-host disease (GVHD). In particular, my efforts are focused on defining the molecular effectors of cell migration with intent to define the optimal method(s) to deliver cells systemically to sites where they are needed. This work fundamentally seeks to improve hematopoietic and immunologic recovery after HSCT and, more broadly, to enable regenerative therapeutics and adoptive immunotherapy. To this end, my laboratory has developed a platform technology called “Glycosyltransferase-Programmed Stereosubstitution” (GPS) to enforce surface sialyl Lewis X (sLeX) carbohydrate substitutions on relevant cells, thereby conferring binding to the selectin class of adhesion molecules. -
MemberEllington Healthcare Asset Management Llc 2016 - PresentMarlton, Nj, UsEllington Healthcare Asset Management LLC manages Ellington Healthcare Partners I, L.P. and is responsible for making all investment decisions for the Partnership. -
MemberNsip Llc 2012 - PresentNSIP LLC is the General Partner of Ellington Healthcare Partners I, L.P. a venture capital investment fund that targets companies with unique therapies using adult stem cells which typically are blood or bone marrow derived, nanotechnology devices, or molecular targeted, oncologic pharmaceuticals that clearly demonstrate potential breakthroughs in the treatment of disease or possess competitive advantages over currently-marketed products.
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Harvard Medical SchoolMedicine/Immunology -
Harvard CollegeGeneral
Frequently Asked Questions about Robert Sackstein Md,Phd
What company does Robert Sackstein Md,Phd work for?
Robert Sackstein Md,Phd works for Harvard Medical School
What is Robert Sackstein Md,Phd's role at the current company?
Robert Sackstein Md,Phd's current role is Director, Program of Excellence in Glycosciences, Harvard Medical School.
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What is Robert Sackstein Md,Phd's direct phone number?
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What schools did Robert Sackstein Md,Phd attend?
Robert Sackstein Md,Phd attended Harvard Medical School, Harvard College.
What skills is Robert Sackstein Md,Phd known for?
Robert Sackstein Md,Phd has skills like Medicine, Transplant.
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