Robert Tighe

Robert Tighe Email and Phone Number

Senior Vice President of Preclinical and Translational Sciences @ Ottimo Pharma
Cambridge, MA, US
Robert Tighe's Location
Cambridge, Massachusetts, United States, United States
Robert Tighe's Contact Details

Robert Tighe personal email

n/a
About Robert Tighe

Biopharmaceutical research executive with extensive experience in immuno-oncology (IO) drug discovery & development. Broad scientific, technical and managerial expertise that spans early discovery (target validation, candidate screening) to IND-enablement (toxicology, DMPK, preclinical efficacy, mechanism-of-action) through early clinical development (IND preparation/authorship, regulatory affairs, clinical CRO selection, biomarker assays). Over 27 years of research experience with over 17 years of industry experience in IO. Proven track record of success in moving novel immunotherapies into the clinic as a major contributor to 5 successful INDs including the NHS-IL12 immunocytokine, the approved anti-PD-L1 antibody Bavencio™, M7824 (anti-PD-L1-TGFb-Trap), CTX-471 (novel, differentiated CD137 agonist), and TC-510 (mesothelin-targeted autologous TRuC T cell therapy enhanced by a PD-1xCD28 chimeric switch receptor).

Robert Tighe's Current Company Details
Ottimo Pharma

Ottimo Pharma

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Senior Vice President of Preclinical and Translational Sciences
Cambridge, MA, US
Website:
ottimopharma.com
Employees:
20
Robert Tighe Work Experience Details
  • Ottimo Pharma
    Senior Vice President Of Preclinical And Translational Sciences
    Ottimo Pharma
    Cambridge, Ma, Us
    View
  • Ankyra Therapeutics
    Chief Scientific Officer
    Ankyra Therapeutics Jul 2023 - Present
    View
  • Tcr² Therapeutics Inc.
    Vice President Research
    Tcr² Therapeutics Inc. Sep 2021 - Jun 2023
  • Tcr² Therapeutics Inc.
    Vp, Translational Research
    Tcr² Therapeutics Inc. Jul 2019 - Sep 2021
  • Compass Therapeutics Llc
    Vice President, Translational Immunology & Immunopharmacology
    Compass Therapeutics Llc Jan 2018 - Jun 2019
  • Compass Therapeutics Llc
    Senior Director, Head Of Translational Immunology & Immunopharmacology
    Compass Therapeutics Llc Mar 2017 - Jan 2018
  • Compass Therapeutics Llc
    Director, In Vivo Pharmacology Immunotherapy
    Compass Therapeutics Llc Dec 2015 - Mar 2017
  • Emd Serono, Inc.
    Associate Director, Immunopharmacology
    Emd Serono, Inc. Apr 2013 - Nov 2015
    Boston, Massachusetts, Us
    View
  • Emd Serono, Inc.
    Group Leader, Translational Immunology
    Emd Serono, Inc. Jan 2011 - Apr 2013
    Boston, Massachusetts, Us
    View
  • Emd Serono, Inc.
    Senior Scientist Ii, Translational Immunology
    Emd Serono, Inc. Jun 2010 - Dec 2010
    Boston, Massachusetts, Us
    View
  • Emd Serono, Inc.
    Associate Scientist In Cancer Immunotherapy & Animal Research Facility Manager
    Emd Serono, Inc. Jan 2005 - Jun 2010
    Boston, Massachusetts, Us
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  • Arqule
    Research Scientist & Animal Facility Manager
    Arqule Sep 2003 - Dec 2004
  • The Jackson Laboratory
    Biomedical Technologist Ii
    The Jackson Laboratory Oct 2001 - Apr 2003
    Bar Harbor, Me, Us
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  • Mit
    Research Assistant
    Mit Oct 1998 - Sep 2001
    Cambridge, Ma, Us
    Research focused on gene therapy targeting hematopoietic stem cells. Coauthor of Science article describing the gene therapy cure of sickle cell anemia in mouse models. Conducted research using a genetic mouse model of erythropoietic protoporphyria (EPP), and co-authored a paper published in the Journal of Investigative Dermatology that reported the amelioration of EPP associated liver and skin toxicity by physiological levels of ferrochelatase.
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  • Whitehead Institute
    Research Assistant
    Whitehead Institute Sep 1994 - Aug 1997
    Cambridge, Massachusetts, Us
    Research conducted in the laboratory of Robert Weinberg. Work focused on exploring the involvement of the DCC gene in colorectal cancer progression. Contributed to research that identified a major role for DCC in axonal guidance in the developing brain and spinal cord; results were published in the journal Nature.
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Robert Tighe Skills

Drug Discovery Immunology In Vitro Cell Oncology Assay Development Drug Development Pharmacology In Vivo Clinical Development Cell Biology Cancer Biomarkers Clinical Trials Stem Cells Vaccines Translational Medicine

Frequently Asked Questions about Robert Tighe

What company does Robert Tighe work for?

Robert Tighe works for Ottimo Pharma

What is Robert Tighe's role at the current company?

Robert Tighe's current role is Senior Vice President of Preclinical and Translational Sciences.

What is Robert Tighe's email address?

Robert Tighe's email address is ro****@****cr2.com

What skills is Robert Tighe known for?

Robert Tighe has skills like Drug Discovery, Immunology, In Vitro, Cell, Oncology, Assay Development, Drug Development, Pharmacology, In Vivo, Clinical Development, Cell Biology, Cancer.

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