Robert W. Wilkinson, Ph.D. Email and Phone Number
An experienced, inspirational oncology drug hunter with deep understanding of small molecule and biologics drug discovery. Helped to bring many new drugs into clinical trials, including a key contributor to the nomination of 13 candidate drugs (CDs) and >10 investigational new drugs (INDs), and 2 launched drugs, Imfinzi® (PD-L1) and Imjudo® (CTLA-4).An authentic leader with a passion for building and leading high-functioning teams/organisations doing groundbreaking cancer research and drug discovery. Strong communicator with a proven ability to influence broadly at all levels, driving innovation and raising scientific quality whilst promoting a culture of trust and mutual integrity.A pioneer in Immuno-oncology (IO) drug discovery, at AstraZeneca/MedImmune proposed PD-L1 as a T cell checkpoint target and devised the drug discovery plan. Since the first approval in 2017, more than 150,000 patients have been treated with Imfinzi®. A core contributor of multiple other IO discovery programs, including Volrustomig (formerly MEDI5752) a bispecific antibody targeting PD1/CTLA-4, currently in Phase III. Recently, conceived AstraZeneca's NextGen IO scientific vision, led the global NextGen IO unit and translated its strategy into action, establishing a sustainable NextGen discovery pipeline.A track record of identifying and implementing novel drug platforms, spanning small molecules (antineoplastic kinase inhibitors, TLR agonists), fusion protein, mono- and bispecific antibodies, antibody-drug conjugates (ADCs), mRNA, and oncolytic virotherapy.An expert scientist in cancer biology, immunology, and drug discovery/translation having presented at national and international scientific meetings and been a co-author on over 85 peer-reviewed publications.
Immunocore
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Vice President, Head Of Oncology ResearchImmunocore Sep 2023 - PresentAbingdon, England, Gb -
Executive Director, Global Head Of Nextgen Immuno-Oncology (Io)Astrazeneca May 2021 - Aug 2023Cambridge, Cambridgeshire, GbAt AstraZeneca I conceived the NextGen IO scientific vision and led a global cross-functional team across UK and US sites. My role involved translating the strategy into tangible action plans. I assumed the responsibility of overseeing and managing the NextGen IO portfolio, ensuring seamless progression of projects from research and target selection through to IND. In under 18 months I established a sustainable NextGen IO pipeline encompassing myeloid and T cell small molecule and biologics approaches. -
Senior Director, Head Of Cambridge Oncology ResearchAstrazeneca May 2019 - May 2021Cambridge, Cambridgeshire, Gb -
Director, Head Of Cambridge Oncology ResearchMedimmune Jan 2012 - May 2019Gaithersburg, Maryland, UsAt Medimmune (a fully owned AstraZeneca group) led the cancer biologics discovery department in Cambridge. Directed projects from target discovery/proof-of-concept to IND filing and translational support, with a ‘commitment to excellence’. Helped to build a strong preclinical and clinical portfolio of novel immuno-oncology and antibody-drug conjugate therapeutics. Developed innovation state-of-the-art capabilities in drug discovery and complex preclinical models of cancer. Managed a talented, multi-disciplined group of scientists and led or participated in numerous industry (e.g., Moderna, Immunocore, 3M) and industry-academia (e.g., AZ-CRUK Antibody Alliance Lab) collaborations, and contribute to overall oncology strategy. -
Principal ScientistAstrazeneca Nov 2008 - Jan 2012Cambridge, Cambridgeshire, GbAt AstraZeneca formed a translational in vivo pharmacology team and delivered datasets to support the preclinical and clinical oncology small molecule pipeline. Worked across multiple areas of cancer biology, including cell cycle, growth factors, vascular modulation, invasion, and immunotherapy. Presented scientific findings at international conferences and co-authored over 30 peer-reviewed papers between 2006 and 2013, on small molecule kinase inhibitors such as Caprelsa®, Iressa®, and Koselugo®.Established AZ’s immunotherapy interests and pipeline, through biologics target proposals in collaboration with Abgenix/Amgen; and was the AZ Lead Biologist on the small molecule TLR7 agonist program in collaboration with Sumitomo Pharma. Led an in vivo pharmacology team which contributed to the discovery of 3 CD nominations and two INDs for Aurora kinase B (Barasertib/AZD1152 and AZD3646) and CDK2 (AZD5438) inhibitors. -
Team Leader, Head Of Discovery Medicine In Vivo (Uk)Astrazeneca Apr 2006 - Nov 2008Cambridge, Cambridgeshire, Gb -
Team LeaderAstrazeneca Apr 2004 - Apr 2006Cambridge, Cambridgeshire, Gb -
Associate Team LeaderAstrazeneca Jun 2001 - Apr 2004Cambridge, Cambridgeshire, Gb -
Team Leader/Post DocCancer Research Technology 1997 - 2001London, Gb
Robert W. Wilkinson, Ph.D. Education Details
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University Of BirminghamExperimental Immunology -
Aston UniversityHuman And Applied Biology
Frequently Asked Questions about Robert W. Wilkinson, Ph.D.
What company does Robert W. Wilkinson, Ph.D. work for?
Robert W. Wilkinson, Ph.D. works for Immunocore
What is Robert W. Wilkinson, Ph.D.'s role at the current company?
Robert W. Wilkinson, Ph.D.'s current role is Vice President, Head of Oncology Research at Immunocore I Focus on Immunotherapies I Passionate about science and delivering better medicines for cancer patients.
What schools did Robert W. Wilkinson, Ph.D. attend?
Robert W. Wilkinson, Ph.D. attended University Of Birmingham, Aston University.
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