Academic advisors:Prof. Akane Kawamura and Prof. Chris J. SchofieldFunding:Cancer Research UK (CRUK)During this postdoctoral research I investigated how post-translational modifications (both canonical and novel) on histone peptides influence recognition by tumour-associated epigenetic enzymes, with a view to early-stage inhibitor discovery.

Academic supervisors: Prof. Andy Wilson and Prof. Richard BaylissFunding:MRC Discovery Medicine North Doctoral Training Partnership (DiMeN DTP)My PhD research combined synthetic chemistry with structural biology and aspects of biophysics to develop constrained peptides as inhibitors of protein-protein interactions linked with cancer progression.1st Place Prize Winner in the #RSCChemBio category of the Royal Society of Chemistry #RSCPoster Twitter Conference… Show more Academic supervisors: Prof. Andy Wilson and Prof. Richard BaylissFunding:MRC Discovery Medicine North Doctoral Training Partnership (DiMeN DTP)My PhD research combined synthetic chemistry with structural biology and aspects of biophysics to develop constrained peptides as inhibitors of protein-protein interactions linked with cancer progression.1st Place Prize Winner in the #RSCChemBio category of the Royal Society of Chemistry #RSCPoster Twitter Conference, March 2022 Show less

Industrial supervisor: Dr. Thomas ScreenAcademic supervisor: Prof. Colin FishwickFunding:This placement was funded by YProTech Ltd. with support from the Royal Society of Chemistry (RSC)During this one year placement I performed synthetic organic chemistry in an industrial lab on a daily basis alongside experienced chemists. I synthesized a library of "building block compound" for use in antibody drug conjugate (ADC) research, including differentially protected… Show more Industrial supervisor: Dr. Thomas ScreenAcademic supervisor: Prof. Colin FishwickFunding:This placement was funded by YProTech Ltd. with support from the Royal Society of Chemistry (RSC)During this one year placement I performed synthetic organic chemistry in an industrial lab on a daily basis alongside experienced chemists. I synthesized a library of "building block compound" for use in antibody drug conjugate (ADC) research, including differentially protected dipeptides and various pyrrolobenzodiazepine (PBD) scaffolds to be used in ADC linker and payload studies, respectively. Show less