Robert Doornbos Email & Phone Number

Ede, Ge, Nl

Utrecht, Utrecht, Nl

Merus is a clinical-stage oncology company developing innovative full-length human bispecific and trispecific antibody therapeutics, referred to as Multiclonics®. Multiclonics® are manufactured using industry standard processes and have been observed in preclinical and clinical studies to have several of the same features of conventional human monoclonal antibodies, such as long half-life and low immunogenicity.The product candidates in the Merus pipeline are based on the Multiclonics® format (full length human IgG antibodies). Our strategy employs the unique attributes of our proprietary bispecific antibodies and our patented screening technologies to engage and harness the power of the immune system to target tumor cells (see merus.nl/pipeline/).Responsible for manufacturing and non-clinical development for Merus’ product candidates from transition from Research to Development up to Product licensure.

Utrecht, Utrecht, Nl

Utrecht, Utrecht, Nl

Utrecht, Utrecht, Nl

ProtAffin has developed the CellJammer® discovery technology to generate biopharmaceutical compounds addressing many high priority disease targets in the pharmaceutical industry. Through this technology ProtAffin has created a pipeline of glycan-binding decoy proteins that cause potent down-regulation of protein function with applications in inflammation, respiratory diseases and oncology. The approach is applicable to over 900 targets contained in a proprietary database, including chemokines and growth factors. Responsibilities: Directing the cross-functional development of preclinical and clinical development projects, including assisting in defining the strategy for such projects.Tasks:- Leading cross-functional teams for the development of PA401 and PA910.- Managing external collaborations in CMC, Toxicology and Bioanalysis & Immunogenicity Testing.- Managing and contributing to Scientific Advice Meetings, the preparation of Orphan Drug Applications and Clinical Trial Applications (CTAs).PA401 was successfully managed from Proof of Concept in animal models into a Phase 1 First in Human study in healthy volunteers.

2595 Da The Hague, Nl

Responsible for sales, science and strategy for bioanalysis at TNO. Bioanalysis includes quantitative and qualitative analysis of small molecules, biopharmaceuticals and anti-drug antibodies in biological matrices using LC-MS/MS, ELISA, RIA and Biacore.

2595 Da The Hague, Nl

GLP Study Director. Managing projects for pharma and biotech companies on development and validation of immunoassays for the quantitative analysis of biopharmaceuticals and the detection of anti-drug antibodies.

Nijmegen, Gelderland, Nl

Project scope: optimization of potato carboxypeptidase inhibitor (PCI), a natural Epidermal Growth Factor Receptor (EGFR) antagonist.

Title of PhD thesis: Regulation of Protein Kinase B (PKB) activity by Protein Kinase C (PKC) zeta.

Doctor Of Philosophy (Phd), Molecular Cell Biology

Master Of Science (Msc), Medical Biology

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