Robert Bauer

Robert Bauer Email and Phone Number

Principal Scientist at Merck Research Labs @ Merck
kenilworth, new jersey, united states
Robert Bauer's Location
Boston, Massachusetts, United States, United States
Robert Bauer's Contact Details

Robert Bauer personal email

n/a

Robert Bauer phone numbers

About Robert Bauer

I am an enzymologist with 16 years of research experience focusing on the purification, kinetic and biophysical characterization of various enzymes with their substrates/small molecules. I have published works utilizing a wide variety of techniques including but not limited to, steady state, pre-steady state and single turnover kinetic analysis, Kintek Global Kinetic Explorer, SPR, and stopped flow spectroscopy and ITC

Robert Bauer's Current Company Details
Merck

Merck

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Principal Scientist at Merck Research Labs
kenilworth, new jersey, united states
Website:
merck.com
Employees:
77695
Robert Bauer Work Experience Details
  • Merck
    Principal Scientist
    Merck Sep 2022 - Present
    Boston, Massachusetts, United States
    Core team Biochem/Biophysics representative for a variety of early and LO stage drug discovery programs in both oncology and immunology spaces employing multiple drugging modalities. Assisted/directed assay development, as well as screening and lead optimization test cascade construction. Managed scientific and career development of two bench facing reports. Scientific mentor/SME for other team members in QB department, and cross functional departments.
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  • Agios Pharmaceuticals
    Associate Director
    Agios Pharmaceuticals Feb 2022 - Aug 2022
    Cambridge, Massachusetts, United States
    Small molecule drug discovery targeting rare genetic diseases; development of novel biochemical and biophysical assays for high throughput screening, hit to lead optimization and routine SAR driving applications. Managing CRO scientists and a direct report involved in both routine data generation as well as exploratory research.This work culminated in one asset which has begun a phase 1 clinical trial (https://clinicaltrials.gov/study/NCT06286033?intr=AG-181&rank=1).
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  • Agios Pharmaceuticals
    Senior Scientist
    Agios Pharmaceuticals Feb 2020 - Jan 2022
    Cambridge, Massachusetts, United States
    Small molecule drug discovery targeting rare genetic diseases; development of novel biochemical and biophysical assays for high throughput screening and routine SAR driving applications. Managing CRO and academic collaborations involved in both routine data generation as well as exploratory research.
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  • Agios Pharmaceuticals
    Scientist
    Agios Pharmaceuticals Mar 2018 - Jan 2020
    Cambridge, Massachusetts
    Ran and developed biochemical assays for two small molecule drug discovery projects targeting rare genetic diseases. My research pertained to the screening for small molecule drug candidates utilizing enzymatic and biophysical techniques, followed by subsequent triage of hits and enabling the understanding of SAR.
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  • Agios Pharmaceuticals
    Enzymologist, Biochemistry
    Agios Pharmaceuticals Apr 2017 - Feb 2018
    Cambridge, Massachusetts, United States
    This position focused on the biochemistry/biophysics side of a drug discovery project pertaining to a rare genetic disease. My research pertained to the enzymatic and biophysical characterization of a variety of drug candidates being developed as potential therapeutic agents.
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  • New England Biolabs
    Postdoctoral Researcher
    New England Biolabs Aug 2014 - Mar 2017
    My postdoctoral studies explored the kinetics of various DNA ligases, but heavily focused on T4 DNA ligase. This work involved detailed steady-state, pre-steady state and single turnover experimental analysis of various steps in the ligation pathway. The goal of the research was to accurately quantitate the microscopic rates of the mechanistic steps using fitting by simulation, and expand the kinetic model of ligation present throughout the literature to more effectively represent the true functionality of this essential class of enzymes.
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  • University Of Pittsburgh
    Graduate Student Researcher
    University Of Pittsburgh Jun 2008 - May 2014
    Greater Pittsburgh Area
    My graduate work pertained to proteins involved in the DNA replication process from the archaeal organism Sulfolobus solfataricus. At the University of Pittsburgh I examined the enzymatic functions of DNA polymerase, primase and helicase enzymes, as well as characterized protein-protein interactions resultant from the formation of higher order complexes of these enzymes with their respective accessory factors.
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Robert Bauer Skills

Protein Purification Enzyme Kinetics Molecular Biology Fluorescence Spectroscopy Protein Protein Interactions Protein Expression Pcr Uv/vis Akta Prime Fast Liquid Protein Chromatography Gel Electrophoresis Aseptic Technique Tlc Protein Chemistry Protein Mutagenesis Fluorescence Anisotropy Biochemistry Assay Development Spr Biophysics Steady State Kinetics Pre Steady State Kinetics Dsf Itc Stopped Flow Spectroscopy

Robert Bauer Education Details

Frequently Asked Questions about Robert Bauer

What company does Robert Bauer work for?

Robert Bauer works for Merck

What is Robert Bauer's role at the current company?

Robert Bauer's current role is Principal Scientist at Merck Research Labs.

What is Robert Bauer's email address?

Robert Bauer's email address is ro****@****ios.com

What is Robert Bauer's direct phone number?

Robert Bauer's direct phone number is (412) 624*****

What schools did Robert Bauer attend?

Robert Bauer attended University Of Pittsburgh, Indiana University Of Pennsylvania.

What are some of Robert Bauer's interests?

Robert Bauer has interest in Politics, Science And Technology, Environment, Health.

What skills is Robert Bauer known for?

Robert Bauer has skills like Protein Purification, Enzyme Kinetics, Molecular Biology, Fluorescence Spectroscopy, Protein Protein Interactions, Protein Expression, Pcr, Uv/vis, Akta Prime Fast Liquid Protein Chromatography, Gel Electrophoresis, Aseptic Technique, Tlc.

Who are Robert Bauer's colleagues?

Robert Bauer's colleagues are David Mathew, Maureen Piercy, Brian Morrissey, Sujatha Guruswamy, Debi Zema, Lorraine Gachko, Anderson Fabian Molina Salazar.

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