GSK insourcing - Researching Organic & Medicinal Chemistry

I worked on the development of novel and greener synthetic methodologies in Organic Chemistry, focused on:- Bifunctional Asymmetric Organocatalysis - Chiral Lewis Base Catalysis + Photocatalysis - Nickel-Catalysed Cross-Electrophile Coupling - Electrochemical Organic Synthesis During this period I've published several articles in international journals with high impact factors and I've given various oral communication at national and international congresses Synthetic & Analytical Skills- Organic synthesis - Photocatalysis - Electrochemistry- Flow photo- & electro- chemical reactions- Asymmetric methodologies Techniques & Equipment- Schlenk line to work with air- & moisture- sensitive compounds- Purification by crystallisation, vacuum destination, preparative TLC & Automatic Flash Column Chromatography - Analysis of samples via 1D and 2D NMR spectroscopy (1H, 13C, 19F & 31P)- Analysis of chiral samples with SFC- GC-MS and HPLC

As part of the Organic Chemistry team, I was involved in:- The synthesis, purification and characterization of target compounds- The analysis, evaluation and optimisation of synthetic routes- Holding regular meetings for the presentation of results and reports Techniques and Equipment:-Hydrogenation reaction (standard & H-Cube)- Automatic Flash Column Chromatography - Analytical UPLC & HPLC- Preparative HLPC - 1H-NMR & 13C-NMR- SciFinder, Reaxys & Web of Science

I was part of the Medicinal Chemistry team, which was involved in:- The synthesis and design of novel organic compounds for the treatment of Third World Diseases (malaria, tuberculosis, Chagas, etc). - Structure-Activity Relationship studies - The evaluation of pharmacokinetic and pharmacodynamic properties- Hit/Lead identification by computational studiesTechniques & Equipment - Microwaved reactions- Greenhouse synthesiser- Lyophilization - Hydrogenation (H-Cube)- Automatic Flash Column Chromatography - Analytical UPLC & HPLC- Preparative HLPC- 1H-NMR & 13C-NMR- SciFinder & MOE- E-Notebook, ChemDraw & MestReNova