Robert G. Schaut, Phd Email & Phone Number

Indianapolis, In, Us

Austin, Texas, Us

Led Collaborative Research: Directed Oracle Health's academic, institutional, and medical center partnership program with external entities. Facilitated membership with Wake Forest Institute of Regenerative Medicine, supported over $200 mm in grants, and added more than 70 industry/biotechnology members to our partnership network.Leveraged Subject Matter Expertise: Utilized background as an immunologist and scientist to provide thought leadership and specialized knowledge to building our appropriate datasets for machine learning models. Assisted in experimental planning and appropriate data security for model development within personalized medicine, drug discovery and translational-biomarker research.Orchestrated Cross-Functional Collaboration: Coordinated cross-functional initiatives within the organization, collaborating with AI/ML developers and with sales/business development. Our team helped to indirectly impact revenue of over $18 mm through Q1 2024.

Provide expert guidance in immunology to drive experimental planning, ensuring optimal study design and execution for a prostate cancer clinical trials (Phase 1/2ab).Utilize immunological expertise to interpret data between preclinical models and translate into clinical protocol development.Met with investment partners to explain scientific background of program, applications of research into the oncology space and comercialization. Secured funding for Series A.

Brookings, South Dakota, Us

Faculty Member and Thesis Committee Advisor | Veterinary & Biomedical Sciences Department | Animal Disease Research and Diagnostic Laboratory· Mentorship and Guidance: Offer valuable guidance and mentorship to PhD students, providing crucial support in their academic and research journeys.· Thesis Committee Membership: Serve as a faculty member within the Veterinary & Biomedical Sciences Department and Animal Disease Research and Diagnostic Laboratory, actively participating in thesis committees to assess and guide PhD students' research progress and scholarly pursuits.

Greenfield, In, Us

Strategic Pipeline Development Leader | Driving Technical Success and De-risking New Assets· Target Identification and De-risking: Play a pivotal role in identifying promising targets for pipeline entry, assessing their potential and implementing strategies to de-risk and enhance the probability of technical success for new assets.· Cross-Functional Coordination: Fostered effective collaboration by coordinating studies and initiatives both internally and externally. Collaborate closely with Contract Research Organizations (CROs), academic institutions, and governmental partners.· Project Leadership: Lead projects from inception to early development, encompassing therapeutic candidates (small/large molecule) and vaccine candidates. Utilize a strategic approach to drive project success and ensure alignment with organizational objectives.· Risk Mitigation and Optimization: Employ analytical skills and industry knowledge to identify potential risks and optimize project timelines, resource allocation, and budget management for efficient and effective project execution.

Greenfield, In, Us

Research/Scientific Project Leader | Cattle, Swine, Poultry, and Aquaculture | Pharmaceuticals, Small Molecule, Biologicals, and Immune-Focusing Compounds· Comprehensive Project Leadership: Spearhead diverse research projects focusing on cattle, swine, poultry, and aquaculture, with a specific emphasis on pharmaceuticals, small molecules, biologicals, and immune-focusing compounds.· Study Sponsorship and Monitoring: Fulfill a pivotal role as a study sponsor and monitor at Contract Research Organization (CRO) sites, ensuring adherence to protocols, regulatory requirements, and quality standards. Oversee study progress, provide guidance, and actively contribute to protocol drafting and finalization, as well as authoring final study reports.· CRO Site Evaluation and Investigator Engagement: Visit prospective CRO sites to assess capabilities, infrastructure, and expertise. Conduct interviews with investigators to select optimal partners for collaborative research and establish strong working relationships.· Immunology Subject Matter Expertise: Act as a trusted subject matter expert in immunology and comparative immunology, leveraging in-depth knowledge to provide critical insights and guide research efforts in the field.

Washington, Dc, Us

Immunology Research Scientist | Shigatoxigenic E. coli (STEC), Enterotoxigenic E. coli (ETEC), and Enterohemorrhagic E. coli (EHEC) Studies | Vaccine Development | Immune-Assay Assessment | Biomolecule Identification· Comprehensive Immunological Research: Investigate the immunological effects of Shigatoxigenic E. coli (STEC), Enterotoxigenic E. coli (ETEC), and Enterohemorrhagic E. coli (EHEC) on the reservoir host. Focus on understanding immunological changes post-vaccination, including the impact on the microbiome.· Vaccine Development and In Vivo Studies: Develop vaccine candidates targeting pathogenic E. coli strains and design in vivo studies to reduce pathogen shedding. Perform immune-assay assessments to evaluate vaccine efficacy, incorporating bioinformatics-based analyses.· In Vivo and In Vitro Immunological Studies: Explore immune effects in vivo and investigate mechanisms of immune function in vitro, specifically examining T cell function, phenotype, transcription profiles, and signaling cascades. Identify biomolecules as indicators of vaccine success or E. coli colonization.· Cellular Immune Responses: Investigate the cellular immune responses of the host to E. coli proteins EspA, EspB, and TIR, analyzing their impact on the immune system.· Laboratory Management and Regulatory Interaction: Plan, manage, direct, and implement immunological studies within the laboratory. Interact with the regulatory agency (APHIS) of the USDA and generate appropriate Institutional Animal Care and Use Committee (IACUC) documentation.

Ames, Iowa, Us

Vaccine Research Scientist | Novel Delivery Platform Development | Humoral Response and Long-Lived Antibody Generation | Assay Development and Standardization· Innovative Delivery Platform: Research novel vaccine and large molecule delivery platform utilizing polyanhydride polymers as an antigen depot, serving as both immune adjuvant and direct antigen-delivery system.· Humoral Response Focus: Investigate humoral responses for driving long-lived antibody response to target antigen, optimizing vaccine efficacy through adjuvant characterization and selection.· Immune Modulation: Study modifications to drive Th1-biased immune responses, targeting soluble versus particulate antigen delivery to lymph nodes at specific immunological time points.· Assay Development and Utilization: Utilize ELISPOT, ELISA, IHC, and flow cytometry for key metrics of vaccine success, developing and standardizing comprehensive assays.· Diverse Vaccination Schemes: Work on varied vaccination schemes including endogenous peptides, Anaplasma spp epitopes, Brucella abortus, and Haemonchus contortus.· Laboratory Operations and Team Supervision: Manage lab operations, supervise students and technical staff to ensure efficient workflow and project execution.

Iowa City, Iowa, Us

Immunology Research Scientist | Leishmania Immune Modulation | Assay Development | Epidemiological Collaboration | Vaccine Development | Diagnostic Testing | Laboratory Management· Leishmania Immune Modulation: Conduct extensive research on immune modulations induced by leishmania, focusing on T cell, B cell, and macrophage populations within the host. Investigate immune regulatory pathways involving PDL1/PD1, TIM-3, and CTLA-4.· Assay Development: Develop and utilize flow cytometry for surface and intra-cell staining, ELISA/luminex, and IHC techniques to study immune responses.· Epidemiological Collaboration: Collaborate with epidemiologists on surveillance of visceral leishmaniasis in the canine reservoir host within the United States.· International Collaborations: Collaborate with research labs in Natal, Brazil (Institute of Tropical Medicine, Federal University of Rio Grande do Norte) and the Infectious Disease Research Institute (IDRI) in Seattle, WA. Conduct research on vaccine candidates and small molecule therapeutics in an endemically infected population, both asymptomatic and clinically symptomatic hosts. Plan follow-up preclinical and clinical trials.· Diagnostic Testing: Play a key role in leishmania infection diagnostics across North America, utilizing qPCR for determination of leishmania infection in dogs. Receive and process clinical samples and perform diagnostic testing.· Laboratory Management: Manage a technician and supervise the clinical laboratory, ensuring smooth workflow and high-quality results.

Des Moines, Iowa, Us

Molecular Biologist and Immunology Expert | Recombinant Protein Expression | Regulatory Compliance | Project Management | Global Collaboration | Team Leadership· Molecular Biology and Immunology Expertise: Served as a knowledgeable expert in immunology, driving future immune-based projects. Specialized in gene cloning, gene/target optimization, transformation, and recombinant protein expression in E. coli, yeast, and bacillus production systems.· Bioassays and Analysis: Conducted bioassays, microorganism identification, HPLC analysis, and PCR gene identification to support research and development efforts.· Regulatory Compliance and Licensing: Implemented and generated regulatory requirements for product licensing in the EU and US. Prepared dossiers for submission to regulatory agencies.· Collaboration with CROs: Collaborated with contract research organizations (CROs) for planning, analysis, and interpretation of immune-based studies.· Project Management and Scale-Up: Managed laboratory-scale projects, overseeing monthly reports and working across departments to bring projects to market. Implemented projects into industrial-level scale-up for commercial production.· Global Team Collaboration: Collaborated with global teams in Belgium and India, ensuring effective communication and coordination for project success.· Team Leadership: Managed interns and provided guidance to technical staff, fostering a productive and cohesive work environment.

Washington, Dc, Us

I study respiratory viral diseases in cattle and how disease effects innate immune function by using techniques such as: flow cytometry, western blot, ELISA and qPCR studying both in an in vivo and in vitro infection setting.Viruses studied include Bovine Respiratory Syncytial Virus (bRSV) a paramyxovirus, and Bovine Viral Diarrhea Virus (BVDV) a non-arthropod borne flavivirus.

Ames, Iowa, Us

Lecturer for pre- medical professional and kinesiology students covering infectious diseases such as viral, bacterial, and parasitic infections in a 90-minute PowerPoint lecture format twice weekly for a class of approximately 80 students. Prepared and graded daily quizzes and final exams as well as general coursework and powerpoints throughout two semesters (Fall 2009-Spring 2010). Helped to grade and quiz students on capstone projects in subsequent semesters.

Worked with genetically modified corn for increased ethanol yield and measured differences in macromolecules present in corn by nuclear magnetic resonance (NMR) and high-performance liquid chromatography (HPLC). Dissected corn and measured tissue weights.

Des Moines, Ia, Us

Work with the lab instructor in development of new and revised labs for nutrition students. Developed labs and procedures on labs such as: cholesterol & lecithin extraction from egg yolks, bomb calorimeter protocol experimenting with food, and protocols on creating reagents to interact with proteins.

Phd, Immunobiology

B.S., Biochemistry, Cellular And Molecular Biology