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To lead and innovate large molecule LCMS biotherapeutic/biomarker bioanalysis strategies to more efficiently characterize a therapy’s affect on one’s quality of life. Target industries: Pharma, CRO, Biotech, Analytical Instrumentation.
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Senior Principal Scientist (Formally Principal And Senior Scientist)Zoetis Inc. Jul 2016 - PresentParsippany, Nj, Us- Leads technology agnostic Translational Biomarkers Team within the Discovery Sciences and Technologies group.- Expertise in quantitative determination of biologics and biomarkers by LCMS. -
Assistant Research Investigator, Lcms Biologics & Biomarkers (Formally Senior Scientist)Q² Solutions Apr 2014 - Jul 2016Durham, North Carolina, Us- Method development scientist experienced in collaborating with internal and external Sponsors to develop selective, high-throughput, quantitative LCMS assays for peptide/protein therapeutics and biomarkers in support of preclinical and clinical programs.- Developed assays range in complexity from simple protein crash/conventional-flow chromatography to complex offline Immunoaffinity (IA) purification coupled to multi-dimensional (2D/3D) online immunocapture, trap and elute nano-flow chromatography.- Provides de novo method development support to Sponsors seeking quantification of a target protein therapeutic/biomarker including determination of optimal digestion strategy for production of a signature peptide for use in bioanalysis.- Supports business development and marketing initiatives through onsite/offsite scientific and capabilities presentations.- Collaborates with instrument and reagent vendors to evaluate new technologies for use in a regulated high-throughput laboratory.- Authors SOPs and work instructions pertaining to implementation of high resolution accurate mass spectrometry (HRMS) instrumentation and software for regulated bioanalysis.- Leads instrument validation activities for equipment and software utilized for large molecule bioanalysis.- Mentors junior scientists through lunch & learn sessions and one-on-one job shadowing.- Bottom-up Applications: Antibody-drug conjugates (ADC), antibodies, biotherapeutics, biomarkers.- Top-down Applications: Utilize Q-Exactive series instrumentation to quantify intact biotherapeutics and biomarkers.Instrument expertise: --- Thermo Q-Exactive, Q-Exactive Plus, TSQ Quantiva, TSQ Vantage mass spectrometers.--- Sciex API 4000, 5000, 5500, 6500 --- Conventional flow Dionex Ultimate 3000 systems, Waters Acquity I-Class, Shimadzu Nexera and Prominence LC platforms. --- Nanoflow Dionex systems (2D, 3D).--- Hamilton STAR and Apricot Designs laboratory automation systems. -
Post-Doctoral Research ScientistQuintiles Sep 2012 - Apr 2014Durham, North Carolina, Us- Post-doctoral research under mentorship of Dr. Jack Henion and Dr. Richard Abbott. - Developed a red blood cell filtration device capable of generating dried plasma spots from whole blood microsamples for use in quantitative bioanalysis.- Implemented high resolution accurate mass spectrometry (HRMS) instrumentation for detection and quantification of small molecules present in complex biological matrices. - Paired high-throughput dried matrix spot extraction technologies with HRMS and triple quadrupole mass analyzers.- Investigated alternative dried blood spot sample treatment workflows and card substrates to address analyte stability and blood hematocrit challenges.- Communicated developments of plasma microsampling strategy at the 2013 ASMS conference in Minneapolis, MN through oral and poster presentation mediums.Instrument expertise: --- Thermo Q-Exactive, Exactive Plus, TSQ Quantiva. --- Dionex and Shimadzu LC systems. --- Spark-Holland dried blood spot autosampler and Symbiosis online SPE systems. -
Research AssistantUniversity Of Wisconsin-Madison Nov 2007 - Sep 2012Madison, Wi, Us- Graduate research under mentorship of Dr. Lingjun Li. - Designed and implemented LC/MS, MS/MS based approaches to characterize and quantify small molecules, peptides, and proteins in complex biological matrices using multiple MS platforms.- Managed a small team junior graduate and undergraduate students.- Coordinated instrument installation, user trainings, and maintenance/troubleshooting.- Six public presentations.- Ten peer reviewed publications.- Thesis: Mass spectrometry method development for targeted and discovery neuroproteomics and peptidomics.Instrument expertise: --- QTOF: Waters micro and Synapt G2. Bruker maXis 4G.--- Ion-trap: Thermo LTQ, Bruker amaZon ETD.--- QQQ: AB Sciex 5500 QTRAP.--- TOF: AB Sciex 4800 MALDI TOF/TOF. Bruker AutoFlex III TOF/TOF.--- Waters Acquity and nanoAcquity UPLC.--- Waters Alliance HPLC. -
Teaching AssistantUniversity Of Wisconsin-Madison Aug 2007 - Dec 2008Madison, Wi, Us- Undergraduate and graduate instruction in laboratory and classroom environment.- Undergraduate instruction: General chemistry and advanced analytical chemistry.- Graduate instruction: Instrumental analysis.- Planned discussion and laboratory sessions.- Demonstrated laboratory safety. -
Research AssistantAquinas College Aug 2006 - May 2007Grand Rapids, Michigan, Us- Research under mentorship of Dr. Elizabeth Jensen.- Developed method to extract and quantify flavonoid content in various varieties of Michigan red wines using analytical flow HPLC coupled to a diode-array detector.- Thesis: Quantification of trans-resveratrol and quercetin in a variety of Michigan red wines. -
Assistant Lab Coordinator - Biology DepartmentAquinas College Aug 2006 - May 2007Grand Rapids, Michigan, Us- Prepared media, slides, and plants for student labs. - Assisted in the upkeep of laboratory rooms and preparation areas. -
Research FellowPierce Cedar Creek Institute May 2006 - Aug 2006- Research under mentorship of Dr. Elizabeth Jensen .- Co-authored competitively funded environmental chemistry research proposal.- Developed collection, extraction, and analysis protocols for measuring heavy metals in soil matrices.- Integrated GPS data into GIS software to graphically display sampling locations in rural and urban West Michigan locations.- Presented research findings orally at two public seminars in West Michigan.- Presented research as a poster at the Central Regional Meeting of the American Chemical Society in Covington, KY.- Research: Quantification of Pb, Zn, & Cu concentrations in various soil types located near heavily trafficked roadways and isolated areas free from vehicle traffic using atomic absorption spectroscopy. -
Lab AssistantFettig Laboratories Aug 2005 - Nov 2005- Performed environmental swabbing and QC testing for pathogens in food products.
Rob Sturm Skills
Rob Sturm Education Details
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University Of Wisconsin-MadisonChemistry (Bioanalytical) -
Aquinas College - Grand RapidsChemistry
Frequently Asked Questions about Rob Sturm
What company does Rob Sturm work for?
Rob Sturm works for Zoetis Inc.
What is Rob Sturm's role at the current company?
Rob Sturm's current role is Translational Biomarker Scientist.
What is Rob Sturm's email address?
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What is Rob Sturm's direct phone number?
Rob Sturm's direct phone number is +160826*****
What schools did Rob Sturm attend?
Rob Sturm attended University Of Wisconsin-Madison, Aquinas College - Grand Rapids.
What are some of Rob Sturm's interests?
Rob Sturm has interest in Chromatography, Ultimate, Environment, Education, Basketball, Mass Spectrometry, Cycling, Science And Technology, Tennis, Golf.
What skills is Rob Sturm known for?
Rob Sturm has skills like Mass Spectrometry, Hplc, Lc Ms, Bioinformatics, Teamwork, Chromatography, Analytical Chemistry, Quantification, Biochemistry, Proteomics, Liquid Chromatography, De Novo Sequencing.
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