Work includes wedding, family, editorial, fashion, and product photography.Follow the link to my formal portfolio: http://www.rodrosetephoto.com

• Experience in oncology studies for clientele, specifically FaDu and EG.7 cell lines. Tumor efficacy studies include small molecule, biologic, CAR-T and DNA plasmid administration through various routes. Other responsibilities included tumor measurements, body weights, and animal observations recorded via StudyLog.• Experience with PK/PD studies, dose scheduling, and dosing for several timepoints after reagent administration. Common responsibilities include blood collection via RO, submandibular, and cardiocentesis, and tissue collection for ex-vivo PD processing. • Performed dosing on mostly rodent species (including hamsters) for several outside clientele. Routes include PO, IP, SC, IN, and IV dosing. Routes of administration in hamsters include PO and IP dosing. • Composed reports upon completion of studies for review to clients• Performed necropsy for tissue harvesting and processed tissue.• Performed extensive disease induction in several mouse models that include tumor models (syngeneic), colitis model (Citrobacter rodentia), and liver fibrosis (CCl4)• Performed tissue culture specifically with RSV related cell lines such as M210B4 (CMV) and Vero.

• Performed dosing on mostly rodent species for potential transport fusion mAbs in UC and CD mouse models.• Established new in-vivo studies with our mAb candidate to study gut transport of said antibody.• Performed ELISA and MSD assays to determine IL-10 levels in homogenized intestinal tissue as well as systemically in plasma• Assigned the task of communicating with CRO’s for studies that cannot be done in house.

• Performed dosing on mostly rodent species for potential Btk inhibitors for B-Cell lymphoma. • Ran ELISA and Western Blotting tests for immune responses to Btk small molecule candidates.• Experience in PK and PD performance in-vivo for DMPK in rodent models.• Performed necropsy for tissue harvesting and processed tissue to run Western blotting for drug and protein detection.• Performed quantification of protein vs. total Btk inhibition with our lead candidate, Ibrutinib• Extensive experience in tumor model implantation that includes murine (CT26, A20, J558, and B16F10) as well as human (TMD8, MINO, JEKO, and DOHH2) cell lines to determine efficacy of our lead candidate, Ibrutinib• Liaison to vendors and CRO within the Bay Area as study monitor for non-GLP studies. Responsibilities include purchase and work order organization, contracts, supply fulfillment, protocol and study design, execution, and completion.

• Performed dosing on mostly rodent species to test a drug for diabetes and obesity, also assisted in dosing animals and necropsy for RN1219, potential candidate for Alzheimer’s disease.• Ran ELISA tests for immune responses to NT-4 and BDNF drugs. • Performed necropsy for tissue harvesting and processed tissue to run Western blotting for drug and protein detection. • Ran Anti-antibody tests on serum samples collected from primate species and rodent species. • Experience in q-Real Time PCR. Familiarity with Qiagen primers as well as RT2 Profiler PCR Array. • Experience in mammalian tissue culture, specifically transfected gD trkB cell lines and Hybridoma cell lines.• Experience in HEK 293 transfection for large scale antibody production.• Some experience in monoclonal antibody purification and isolation. • Developed an Anti-NT4 ELISA for NT4 detection in serum based PK assays. • Instrumental in the development, research, and testing of a new anti-Glucagon Receptor (a-GGNr) monoclonal antibody in-vivo to enhance insulin sensitivity for the alleviation of T2D. • Instrumental in the development, research, and testing of potential a-IL-7R monoclonal antibody candidate in-vivo to aid in the depletion of T-Cells in Systemic Lupus Erthymatosus animal models; NZB/W and MRL-Fas animal models. • Familiar with the BD LSRII FACS Analyzer, ACE Alera Clinical Chemistry Analyzer, Luminex Multiplex analyzer, Mutli-Spot assay and SECTOR Analyzer by MSD, Western Blotting techniques, ELISA, AB StepOnePlus and Viia7 PCR Thermocyclers from Applied Biosciences.

Performed dosing on rodent species such as mice and rats, lagomorphs, and canines for potential drug candidates for outside clientele. Routes include PO, IP, ID, IM, and IV dosing.Study monitor in both GLP and non-GLP settings. Performed PK and toxicology studies under GLP settingsObtained biological samples, processed samples, performed clinical observations, anesthesia, euthanasia, andnecropsy.