Roger Fachini Email & Phone Number

Richmond, CA, US

San Francisco, US

• Freelance work training multimedia (ex. images and audio) Large Language Model AI chatbots using biological subject prompt engineering with Natural Language Processing
• Training AI models with complex and precise prompt engineering
• Application of subject matter expertise for evaluating and ranking the precision and relevance of responses generated by AI models
• Generation of ideal responses for AI model training

Somerset, NJ, US

Temporary contract position in upstream antibody production (cloning, transient and stable mammalian expression, purification, and analysis)

Hercules, CA, US

• Manufacturing Sciences and Technology Staff Scientist optimizing recombinant protein manufacturing, microbiology, molecular biology, and other methods for a variety of Bio-Rad products.
• Saved Bio-Rad $1M within first six months at the company.
• Prevented costly product backorders by insourcing protein production before supplier shortages happened.
• Optimization and authoring of production procedures
• Interfacing with R&D, Manufacturing, and CMOs
• Process Transfer and Scale-up of fermentation methods

New York, NY, US

• Confidential consulting advising researchers or investors on biotechnology/pharmaceutical drug development.

Thousand Oaks, CA, US

• Protein expression, purification, antibody engineering, library construction, and FACS analysis to support early-stage drug discovery projects.
• Enabled clinical trials by improving binding of a PK ELISA antibody to a cytokine over 50-fold in order to increase sensitivity by using yeast library affinity maturation and FACS.
• Identified bispecific antibody formats with correct light chain pairing by designing, expressing, and testing many variants.
• Greatly improved binding of novel engineered antibodies using yeast library affinity maturation.
• Managed R&D interns.
• Enhanced laboratory record keeping with Electronic Lab Notebook programs and piloted their use in actual laboratory conditions. Trained employees in ELN use using customized instructional materials, SOPs, and Guidelines.

Thousand Oaks, CA, US

• Protein Expression, Microbial Cloning, Assay Development, Drug Discovery Project Representative
• Initiated a protein-based drug development program for diabetes by designing and creating a highly efficacious fusion protein.
• Saved over $100,000 per reagent and advanced dozens of research projects by producing protein reagents internally using bacterial and baculoviral expression systems.
• Secured employee safety by writing Amgen’s first Job Hazard Assessment in the Research department and serving as a Laboratory Safety Representative.

Thousand Oaks, CA, US

• Molecular Cloning, Protein Expression, Vector Development, Protein Engineering
• Started a drug development program for HIV by initiating a collaboration with UCLA for testing of protein therapeutics.
• Advanced drug development programs by developing crucial assays to improve sensitivity and increase throughput.

Thousand Oaks, CA, US

• Fermentor operation, metabolite analysis, protein expression, molecular cloning, bacterial promoter optimization
• Enhanced protein expression in plasmid vector systems by improving promoter control and strength using directed evolution of proteins.

Thousand Oaks, CA, US

• HPLC, Fermentor operation, molecular cloning, protein expression, vector development
• Created a new pharmaceutical product by learning molecular cloning in order to produce a variant of KGF that was marketed as Kepivance.

• Fermentor operation, HPLC, microbial culture process improvement, antibiotic and amino acid production. Employee training.
• Supported an international research collaboration by efficiently analyzing fermentation production of amino acids using HPLC.
• Improved the visibility of research operations by presenting progress to the Board of Directors.

Master Of Science (M.S.), Biochemistry

Bachelor Of Science (B.S.), Biology