Rosalind L. Ang, Ph.D

Rosalind L. Ang, Ph.D Email and Phone Number

Associate Principal Scientist at Merck & Co Inc @ Merck
Rosalind L. Ang, Ph.D's Location
Wayne, New Jersey, United States, United States
Rosalind L. Ang, Ph.D's Contact Details

Rosalind L. Ang, Ph.D personal email

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About Rosalind L. Ang, Ph.D

* Innate immuno-response against cellular fate outcome: survival or death.* Development of new strategies against pathological consequences of inflammation e.g. solid transplant rejection and auto-inflammation. Specialties: TNF, GPCR Mediated Signaling, Molecular Biology, Inflammation, Transplant Immunology, Cognition and Behavioral Response.

Rosalind L. Ang, Ph.D's Current Company Details
Merck

Merck

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Associate Principal Scientist at Merck & Co Inc
Website:
merck.es
Employees:
158
Rosalind L. Ang, Ph.D Work Experience Details
  • Merck
    Associate Principal Scientist, Biologics - Analytical Research & Development
    Merck Aug 2020 - Present
    *SME of analytical methods for host cell related and product related impurities.*Works collaboratively with multi-functional groups (including upstream, downstream, CMC, QC, QA, and MMD teams and CROs) to drive products through pipeline and into commercialization.*Responsibilities include but not limited method development/ transfer/ remediation and authoring methods and regulatory documents.
  • Bristol-Myers Squibb
    Scientist, Cell Therapy Development & Operations
    Bristol-Myers Squibb Nov 2018 - Aug 2020
    Nj
    *Subject Matter Expert (SME) in assay development and product characterization.*Perform technology transfer.*Works collaboratively with multi-functional groups to drive product though the pipeline.*Liaison between Analytical Development and Quality Control Divisions.*Led Quality Control investigation in CAR-T program.*Identified deficiency and provided resolution to improve Quality Control released assays and streamline workflow within the function.
  • Icahn School Of Medicine At Mount Sinai
    Instructor/Postdoctoral Associate
    Icahn School Of Medicine At Mount Sinai Mar 2011 - Nov 2018
    Ny
    *Proficient in using genetic and molecular approaches to study the consequences of cell death signaling mediating apoptotic and necroptotic death. *Developed and established in vivo murine model to study the physiological relevance of these deaths. *Identified the physiological relevance of CYLD mediated necroptotic deaths in inflammatory disorder. *Determined immune consequences of cellular deaths in prolonged cold ischemia heterotopic cardiac allograft transplant, using a murine model that mimics clinical setting.*Presented my findings in 16th TNF Superfamily meeting (Singapore 2017), and in American Transplant Congress 2017 (Chicago, USA) and in American Transplant Congress 2018 (Seattle, USA). *Techniques: SiRNA, Lentiviral and retrovirus transudction, Crispr, Western Blotting, Elispot, Luminex, Flow Cytometry, CyTOFF, IHC, IF, qPCR
  • New York Academy Of Sciences
    Academy Education Fellow
    New York Academy Of Sciences Sep 2011 - Dec 2011
    New Jersey
    * Taught STEM (Science, Technology, Engineering and Mathematics) program in Newark.
  • Mount Sinai School Of Medicine
    Graduate Research Associate
    Mount Sinai School Of Medicine Aug 2003 - Apr 2010
    *Identified dimerization of serotonin 2A receptor and metabotopic glutamate receptor 2 * Showed that the heterodimers are key molecular players in cortical neurons that are necessary and essential for the elicitation of hallucinogen dependent behavioral responses.* Identified pertussis toxin-sensitive heterotrimeric Gi/o proteins and Src to be responsible for the unique hallucinogenic specific genetic signature . * Proficient in genetic and signal transduction studies and mouse work.
  • Nathan Kline Insititute For Psychiatry Research, New York, Ny
    Research Associate
    Nathan Kline Insititute For Psychiatry Research, New York, Ny 2001 - 2003
    Working as a research associate in Dr. Daniel C. Javitt’s research group (The Nathan S. Kline Institute For Psychiatric Research, NY, USA), I assist in performing experiments that examines the chemical balance in brains of rodent models that were given phencyclidine (PCP). The goal of Dr. Javitt’s research is to elucidate how the brain is altered during episodes of schizophrenic attack. My collaboration with Dr. Rokovska and other researchers generated a publication that provides a renewed appreciation for the interplay between striatal acetylcholine and somatostation in dopaminergic interaction. (PMID: 1367952)

Rosalind L. Ang, Ph.D Skills

Research In Vivo Science Molecular Biology Cell Signaling Cell Culture Virology Cell Biology

Rosalind L. Ang, Ph.D Education Details

Frequently Asked Questions about Rosalind L. Ang, Ph.D

What company does Rosalind L. Ang, Ph.D work for?

Rosalind L. Ang, Ph.D works for Merck

What is Rosalind L. Ang, Ph.D's role at the current company?

Rosalind L. Ang, Ph.D's current role is Associate Principal Scientist at Merck & Co Inc.

What is Rosalind L. Ang, Ph.D's email address?

Rosalind L. Ang, Ph.D's email address is an****@****ail.com

What is Rosalind L. Ang, Ph.D's direct phone number?

Rosalind L. Ang, Ph.D's direct phone number is +186222*****

What schools did Rosalind L. Ang, Ph.D attend?

Rosalind L. Ang, Ph.D attended Icahn School Of Medicine At Mount Sinai, National University Of Singapore, Liverpool John Moores University.

What skills is Rosalind L. Ang, Ph.D known for?

Rosalind L. Ang, Ph.D has skills like Research, In Vivo, Science, Molecular Biology, Cell Signaling, Cell Culture, Virology, Cell Biology.

Who are Rosalind L. Ang, Ph.D's colleagues?

Rosalind L. Ang, Ph.D's colleagues are Aza Ismael, Jorge Beltran, Vatsavai Ramachandra Raju, Gloria Landolfi, Carlos Vera, Marc Schmitt, John Adamson.

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