Ryan Thomas Email & Phone Number

Vancouver, British Columbia, Canada

Generated key data under tight timelines to enable go-no-go decisions for multiple early stage programs-successfully enabling transition to exploratory status for 2 programsThrough literature review and scientific insight, supported early stage, exploratory efforts by enhancing team´s understanding of mechanistic pathways, helping steer early stage.

Burnaby, British Columbia, Canada

Led assay development efforts to support immuno-oncology program through literature review and consultation with resident immunologists: developed project plan including scope, timeline and acceptance criteria for complex co-culture assaysSupervised a direct report (Co-op student), fostering skill development in routine lab activities and ensured.

Burnaby, British Columbia, Canada

Burnaby, British Columbia

• Designed and executed pre-clinical tests of drug efficacy of a novel lead compound in MPS I and Gaucher disease patient derived fibroblasts
• Established a collaborative relationship with an investigator in Australia and employed their facilities to further investigations into drug efficacy
• Managed and coordinated different facets of the drug efficacy project with multiple collaborators
• Negotiated access to colleague’s level 2 facilities to expand the lab’s cell culture capabilities
• Presented findings and project updates at regular lab and joint lab meetings
• Assisted the PI in the writing of annual progress reports to funding agency as well as a provisional patent

Burnbay, British Columbia

• Demonstrated efficacy, in a plant model system, of a novel lead compound in enhancing intra-cellular transport of recombinant human proteins involved in 3 separate lysosomal storage diseases
• Transcriptomic profiling and large-scale data analysis with R to generate a hypothesized mechanism of action of the novel drug lead
• Optimized and implemented protocols to test my hypothesis derived from microarray results
• Published a review of screening strategies employed to identify drug leads for lysosomal storage diseases
• Organized committee meetings, evaluated project progress, and wrote annual progress reports

Burnaby, British Columbia

Biology 100- Prepared and conducted weekly tutorial sessions to provide in-depth reviews of lecture material- Assisted in the running and supervision of weekly teaching lab sessions to introduce basic biological concepts.

Burnaby, British Columbia

BICS 366 - Plant Physiology-Conducted weekly tutorials to address student questions and concerns regarding lecture material-Adapted tutorial sessions and office hours to provide greater degrees of student coaching and guidance in preparation for term presentations

Vancouver, Canada Area

• Troubleshooted and optimized procedures and methods enabling me to successfully generate constructs for transformation into mouse NIH 3T3 fibroblasts
• Generated publication worthy data towards the investigation into the role of eEF2 kinase in conferring tumor cell adaptation to metabolic stress
• Summarized and presented experimental results and key findings during lab meetings and in a written, end of term report

Advanced Project Management

Certificate

Master Of Science (M.Sc.), Cell/Cellular And Molecular Biology

Activities and Societies: SFU Iaido Club[Elucidating the mechanism of action of a small molecule proteostasis regulator with potential.

Bachelor Of Science (B.Sc.), Cell/Cellular And Molecular Biology